Research

Synthesis of Enantioenriched Building Blocks

Many biologically important compounds contain a chiral center who’s absolute configuration is critical for activity.  Compounds found in nature that are identified…

Asymmetric Trifluoromethylation Reactions

In recent years, fluorine containing molecules have become important in the pharmaceutical and agrochemical industries, and in particular, the trifluoromethyl group appears…

New Drug Scaffolds

Despite recent advances in drug therapies for diseases such as cancer and malaria there is an essential need for ever more innovative…