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“Synergy and antagonism in natural product extracts: when 1 + 1 does not equal 2.”
Caesar, L. K., & Cech, N. B. (2019).
Nat Prod Rep.


“Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense”
Parlet, C. P., Kavanaugh, J. S., Crosby, H. A., Raja, H. A., El-Elimat, T., Todd, D. A., . . . Horswill, A. R. (2019).
Cell Rep, 27(1), 187-198.e186.


“Quorum sensing between bacterial species on the skin protects against epidermal injury and atopic dermatitis.”
Williams, M. R., Costa, S. K., Zaramela, L. S., Kahil, S., Daniel A. Todd, Heather L. Winter, Sanford, J. A., O’Neill, A. M., Liggins, M. C., Nakatsuji, T., Nadja B. Cech, Cheung, A. L., Zengler, K., Horswill, A. R., Gallo, R. L.
Science Translational Medicine, 11, pii: eaat8329.
doi: 10.1126/scitranslmed.aat8329


“Mapping the Fungal Battlefield: Using in situ Chemistry and Deletion Mutants to Monitor Interspecific Chemical Interactions Between Fungi.”
Sonja L. Knowles, Huzefa A. Raja, Wright, A. J., Lee, A. M., Lindsay K. Caesar, Nadja B. Cech, Mead, M. E., Steenwyk, J. L., Ries, L. N. A., Goldman, G. H., Rokas, A., Nicholas H. Oberlies.
Frontiers in Microbiology, 19, 10:285.
doi: 10.3389/fmicb.2019.00285


“MroQ is a Novel Abi-domain Protein That Influences Virulence Gene Expression in Staphylococcus aureus via Modulation of Agr Activity.”
Stephanie Marroquin, Brittney Gimza, Brooke Tomlinson, Michelle Stein, Andrew Frey, Rebecca A. Keogh, Rachel Zapf, Daniel A. Todd, Nadja B. Cech, Ronan K. Carroll, Lindsey N. Shaw.
Infection and Immunity, pii: IAI.00002-19.
doi: 10.1128/iai.00002-19


“Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing.”
Paguigan, N. D.; Rivera-Chávez, J.; Stempin, J. J., Mario Augustinović, Noras, A. I., Huzefa A. Raja, Daniel A. Todd, Triplett, K. D.; Day, C.; Figueroa, M.; Hall, P. R., Nadja B. Cech, Nicholas H. Oberlies.
Journal of Natural Products, 82, 550-558.
PMID: 30730742; doi: 10.1021/acs.jnatprod.8b00925


“Opportunities and Limitations for Untargeted Mass Spectrometry Metabolomics to Identify Biologically Active Constituents in Complex Natural Product Mixtures.”
Lindsay K. Caesar, Joshua J. Kellogg, Olav M. Kvalheim, Nadja B. Cech.
Journal of Natural Products, 82, 469-484.
PMID: 30844279; doi: 10.1021/acs.jnatprod.9b00176


“Selection and Characterization of Botanical Natural Products for Research Studies: A NaPDI Center Recommended Approach.”
Joshua J. Kellogg, Mary F. Paine, Jeannine S. McCune, Nicholas H. Oberlies, Nadja B. Cech.
Nat. Prod. Rep., Advance Article
doi: 10.1039/C8NP00065D 

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“Detection of adulteration in Hydrastis canadensis (goldenseal) dietary supplements via untargeted mass spectrometry-based metabolomics.”
Diane E. Wallace, Nicholas H. Oberlies, Nadja B. Cech, Joshua J. Kellogg.
Food Chem. Toxicol., 120, 439-447.
PMID: 30031041; doi: 10.1016/j.fct.2018.07.033


“Phytochemical Analysis and Antimicrobial Efficacy of Macleaya cordata against Extensively Drug-Resistant Staphylococcus aureus.”
Manead M. Khin,  Alan M. Jones, Nadja B. Cech, Lindsay K. Caesar.
Natural Products Communications,
13, 1479-1483.
doi: 10.1177/1934578X1801301117


“Analytical methods for the study of bioactive compounds from medicinally used Echinacea species.”
Bruni R., Brighenti V., Lindsay K. Caesar, Bertelli D., Nadja B. Cech, Pellati F.
Journal of Pharmaceutical and Biomedical Analysis, 160, 443-477.
PMID: 30142565; doi: 10.1016/j.jpba.2018.07.044


“Integration of biochemometrics and molecular networking to identify antimicrobials in Angelica keiskei.”
Lindsay K. Caesar, Joshua J. Kellogg, Olav M. Kvalheim, Cech, R. A., Nadja B. Cech.
Planta Med., 84, 721-728.
PMID: 29571174; doi: 10.1055/a-0590-5223


“Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics.”
Lindsay K. Caesar, Olav M. Kvalheim, Nadja B. Cech.
Analytica Chimica Acta., 1021, 69-77.
doi: 10.1016/j.aca.2018.03.013


“Identification of intestinal UDP-Glucoronosyltransferase inhibitors of green tea (Camellia sinensis) using a biochemometric approach.”
Tian, D. D., Joshua J. Kellogg, Okut, N.; Nicholas H. Oberlies, Nadja B. Cech, Shen, D. D.; McCune, J. S.; Paine, M. F.
Drug Metab. Dispos., 46, 552-560.
PMID: 29467215; doi: 10.1124/dmd.117.079491


“Mast cell degranulation and calcium influx are inhibited by an Echinacea purpurea extract and the alkylamide dodeca-2E,4E-dienoic acid isobutylamide.”
Gulledge, T. V., Colette, N. M., Mackey, E, Johnstone, S. E., Moazami, Y., Daniel A. Todd, Moeser, A. J.; Pierce, J. G., Nadja B. Cech, Laster, S. M.
J. Ethnopharmacol., 212, 166-174.
PMID: 29042288; doi: 10.1016/j.jep.2017.10.012


“Biochemometrics to identify synergists and additives from botanical medicines: A case study with Hydrastis canadensis (Goldenseal).”
Emily R. Britton, Joshua J. Kellogg, Kvalheim, O. M., Nadja B. Cech.
Journal of Natural Products, 81, 484-493.
PMID: 29091439; doi: 10.1021/acs.jnatprod.7b00654


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“Coagulase-Negative Staphylococcal Strain Prevents Staphylococcus aureus Colonization and Skin Infection by Blocking Quorum Sensing.”
Paharik, A. E.; Parlet, C. P.; Chung, N., Daniel A. Todd, Rodriquez, E. L., Van Dyke, M. H., Nadja B. Cech, Horswill A. R.
Cell Host Microbe, 22(6), 746-756.
PMID: 29199097; doi: 10.1016/j.chom.2017.11.001


“Interspecific and intraspecific hybrid Epichloë species symbiotic with the North American native grass Poa alsodes.”
Shymanovich, T; Charlton, N. D.; Musso, A. M.; Scheerer, J; Nadja B. Cech, Stanley H. Faeth, Young, C. A.
Mycologia, 109(3), 457-474.
PMID: 28723242; doi: 10.1080/00275514.2017.1340779


“Conventional and accelerated-solvent extractions of green tea (Camellia sinensis) for metabolomics-based chemometrics.”
Joshua J. Kellogg, Diane E. Wallace, Tyler N. Graf, Nicholas H. Oberlies, Nadja B. Cech.
Journal of Pharmaceutical and Biomedical Analysis, 145, 604-610.
PMID: 28787673; doi: 10.1016/j.jpba.2017.07.027


“Signal Biosynthesis Inhibition with Ambuic Acid as a Strategy to Target Antibiotic-Resistant Infections.”
Daniel A. Todd, C. P. Parlet, H. A. Crosby, C. L. Malone, K. P. Heilmann, Alex R. Horswill, Nadja B. Cech.
Antimicrobial Agents and Chemotherapy, 61, pii: e00263-17.
PMID: 28607020; doi: 10.1128/AAC.00263-17


“Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study.”
Joshua J. Kellogg, Tyler N. Graf, Mary F. Paine, Jeannine S. McCune, Olav M. Kvalheim, Nicholas H. Oberlies, Nadja B. Cech.
Journal of natural products, 80 (5), 1457-1466.
PMID: 28453261; doi: 10.1021/acs.jnatprod.6b01156


“Secondary Metabolites from the leaves of goldenseal (Hydrastis canadensis).”
Martha Leyte-Lugo, Emily R. Britton, Daniel H. Foil, Adam R. Brown, Daniel A. Todd, Jose Rivera Chavez, Nicholas H. Oberlies, Nadja B. Cech.
Phytochemistry Letters, 20, 54-60.

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qNMR for profiling the production of fungal secondary metabolites.
Wilson C. Brooks, Noemi D. Paguigan, Huzefa A. Raja, Franklin J. Moy, Nadja B. Cech, Cedric J. Pearce, Nicholas H. Oberlies.
Magnetic resonance in chemistry, 55, 670-676..
PMID: 28024162;  doi: 10.1002/mrc.4571


“Antimicrobial fungal endophytes from the botanical medicine goldenseal (Hydrastis canadensis).”
Joseph M. Egan, Amninder Kaur, Huzefa A. Raja, Joshua J. Kellogg, Nicholas H. Oberlies, Nadja B. Cech.
Phytochemistry Letters, 17, 219-225.


“Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells.”
Amninder Kaur, Martina Oberhofer, Monika Juzumaite, Huzefa A. Raja, Travis V. Gulledge, Diana Kao, Stanley H. Faeth, Scott M. Laster, Nicholas H. Oberlies, Nadja B. Cech.
Natural Product Communications, 11 (8), 1143-1146.
PMID: 28479944


“A Review of the Medicinal Uses and Pharmacology of Ashitaba.”
Lindsay K. Caesar, Nadja B. Cech.
Planta Medica, 82 (14), 1236-45
PMID: 27399234;  doi: 10.1055/s-0042-110496


“Hybrid Quadrupole-Orbitrap mass spectrometry for quantitative measurement of quorum sensing inhibition.”
Daniel A. Todd, David. B. Zich, Keivan. A. Ettefagh, Jeffrey. S. Kavanaugh, Alex R. Horswill, Nadja B. Cech.
Journal of Microbiological Methods, 127, 89-94.
PMID: 27237773;  doi: 10.1016/j.mimet.2016.05.024


“A validated UHPLC-tandem mass spectrometry method for quantitative analysis of flavonolignans in milk thistle (Silybum marianum) extracts.”
Tyler N. Graf, Nadja B. Cech, S. J. Polyak, Nicholas J. Oberlies.
Journal of Pharmaceutical and Biomedical Analysis, 126, 26-33.
PMID: 27136284;  doi: 10.1016/j.jpba.2016.04.028


“Biochemometrics for natural products research: Comparison of data analysis approaches and application to the identification of bioactive compounds.”
Joshua J. Kellogg, Daniel A. Todd, Joseph M. Egan, Huzefa A. Raja, Nicholas H. Oberlies, Olav M. Kvalheim, Nadja B. Cech.
Journal of Natural Products, 79 (2), 376-86
PMID: 26841051; doi: 10.1021/acs.jnatprod.5b01014


“Comparison of electrospray ionization and atmospheric pressure photoionization liquid chromatography mass spectrometry methods for analysis of ergot alkaloids from endophyte- infected sleepygrass (Achnatherum robustum).”
Alan K. Jarmusch, Ashley M. Musso, Tatsiana Shymanovich, Scott A. Jarmusch, Mary Beth E. Lovin, Brandie M. Ehrmann, Susanna Saari, David E. Nichols, Stanley H. Faeth, Nadja B. Cech.
Journal of Pharmaceutical and Biomedical Analysis, 117, 11-17.
PMID: 26340558; doi: 10.1016/j.jpba.2015.08.031

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“A new mass spectrometry based bioassay for the direct assessment of hyaluronidase activity and inhibition.”
Emily R. Britton, Carolyn B, Ibberson, Alexander R. Horswill, Nadja B. Cech.
Journal of Microbiological Methods, 119, 163-167.
PMID: 26519769; doi: 10.1016/j.mimet.2015.10.019


“Cytokine-suppressive activity of a hydroxylated alkylamide from Echinacea purpurea.”
Martha Leyte-Luge, Daniel A. Todd, Tyler V. Gulledge, Emily R. Britton, Monika Juzumaite, Fred S. Carter, Scott M. Laster, Nadja B. Cech.
Planta Medica Letters, 2, e25-e27.
doi: 10.1055/s-0035-1557764


“ω-Hydroxyemodin limits Staphylococcus aureus quorum sensing-mediated pathogenesis and inflammation.”
Seth M. Daly, Barry O. Elmore, Jeffrey S. Kavanaugh, Kathleen D. Triplett, Mario Figueroa, Huzefa A. Raja, Tamam El-Elimat, Heidi A. Crosby, Jon K Femling, Nadja B. Cech, Alexander R. Horswill, Nicholas H. Oberlies, Pamela R. Hall.
Antimicrobial Agents and Chemotherapy, 59, 2223-2235.
PMID: 25645827; doi: 10.1128/AAC.04564-14


Echinacea purpurea extracts contain a mixture of cytokine-suppressive and cytokine-inducing compounds, including some that originate from endophytic bacteria.”
Daniel A. Todd, Tyler V. Gulledge, Emily R. Britton, Martina Oberhofer, Martha Leyte-Lugo, Ashley A. Moody, Tatsiana Shymanovich, Laura F. Grubbs, Monika Juzumaite, Tyler N. Graf, Nicholas H. Oberlies, Stanley H. Faeth, Scott M. Laster, Nadja B. Cech.
Plos One, 10(5).
PMID: 25933416; doi: 10.1371/journal.pone.0124276


“A mass spectrometry-based assay for improved quantitative measurements of efflux inhibition.”
Adam R. Brown, Keivan A. Ettefagh, Daniel A. Todd, Patrick S. Cole, Joseph M. Egan, Daniel H. Foil, Tyler N. Graf, Bryan D. Schindler, Glen W. Kaatz, Nadja B. Cech.
Plos One, 10(5).
PMID: 25961825; doi: 10.1371/journal.pone.0124814

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“Comparison of the chemistry and diversity of endophytes isolated from wild-harvested and greenhouse-cultivated yerba mansa (Anemopsis californica).”
R. Owen Bussey III, Amninder Kaur, Daniel A. Todd, Joseph M. Egan, Tamam El-Elimat, Tyler N. Graf, Huzefa A. Raja, Nicholas H. Oberlies, Nadja B. Cech.
Phytochemistry Letters11, 202-208.
PMID: 25642298; doi:10.1016/j.phytol.2014.12.013


“Investigations of analyte-specific response saturation and dymanic range limitations in atmospheric pressure ionization mass spectrometry.”
Clint Alfaro, Agbo-Oma Uwakweh, Daniel A. Todd, Brandie M. Ehrmann, Nadja B. Cech.
Analytical Chemistry86, (21), 10639-10645.
PMID:25268329; doi: 10.1021/ac502984a


“Polyhydroxyanthraquinones as quorum sensing inhibitors from the guttates of Penicillium restrictum and their analysis by desorption electrospray ionization mass spectrometry.”
Mario Figueroa, Alan K. Jarmusch, Huzefa A. Raja, Tamam El-Elimat, Jeffrey S. Kavanaugh, Alexander R. Horswill, R. Graham Cooks, Nadja B. Cech, Nicholas H. Oberlies.
Journal of Natural Products77, 1351-1358.
PMID:24911880; doi: 10.1021/np5000704


“Staphylococcus epidermidis agr quorum-sensing system: Signal identification, cross talk, and importance in colonization.”
Michael E. Olson, Daniel A. Todd, Carolyn R. Schaeffer, Alexandra E. Paharik, Michael J. Van Dyke, Henning Buttner, Paul M. Dunham, Holger Rohde, Nadja B. Cech, Paul D. Fey, Nadja B. Cech, Alexander R. Horswill.
Journal of Bacteriology196, 3482-3493.
PMID:25070736; doi: 10.1128/JB.01882-14


“Identification of morphological and chemical markers of dry- and wet-season conditions in female Anopheles gambiae mosquitoes.”
Kaira M. Wagoner, Tovi Lehmann, Diana L. Huestis, Brandie M. Ehrmann, Nadja B. Cech, Gideon Wasserberg.
Parasites & Vectors7, 294.
PMID:24970701; doi: 10.1186/1756-3305-7-294


“Antimycobacterial furofuran lignans from the roots of Anemopsis californica.”
R. Owen Bussey III, Arlene A. Sy-Cordero, Mario Figueroa, Fred S. Carter, Joseph O. Falkinham III, Nicholas H. Oberlies, Nadja B. Cech.
Planta Medica80, 498-501.
PMID:24687738; doi: 10.1055/s-0034-1368352


“CodY-mediated regulation of the Staphylococcus aureus Agr system integrates nutritional and population density signals.”
Agnès Roux, Daniel A. Todd, Jose V. Velázquez, Nadja B. Cech, and Abraham L. Sonenshein.
Journal of Bacteriology, Epub ahead of print.
PMID:24391052; doi: 10.1128/JB.00128-13


“Flavonolignans from <em>Aspergillus iizukae</em>, a fungal endophyte of milk thistle (Silybum marianum).”
Tamam El-Elimat, Huzefa A. Raja, Tyler N. Graf, Stan H. Faeth, Nadja B. Cech, and Nicholas H. Oberlies.
Journal of Natural Products, Epub ahead of print.
PMID:24456525; doi: 10.1021/np400955q

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“Small molecule quorum quenchers for prevention of Staphylococcus aureus infection.”
Nadja B. Cech and Alexander R. Horswill.
Future Microbiology, (Editorial), 8, 1-4
PMID:24266350; doi: 10.2217/fmb.13.134


“Strategies and pitfalls in the application of mass spectrometry to natural products research.”
Nadja B. Cech.


“A high-resolution MS, MS/MS, and UV database of fungal secondary metabolites as a dereplication protocol for bioactive natural products.“
Tamam El-Elimat, Mario Figueroa, Brandie M. Ehrmann, Nadja B. Cech, Cedric Pearce, and Nicholas H. Oberlies.
Journal of Natural Products76, 1709-1716
PMID:23947912; doi: 10.1021/np4004307


“Rapid quantitation of furanocoumarins and flavonoids in grapefruit juice using ultra performance liquid chromatography.”
Karen M. Vandermolen, Nadja B. Cech, Mary F. Paine, and Nicholas H. Oberlies.
Phytochemistry24, 654-660
PMID:23780830; doi: 10.1002/pca.2449


“Quantitative analysis of autoinducing peptide I (AIP-I) from Staphylococcus aureus cultures using ultrahigh performance liquid chromatography – high resolving power mass spectrometry.”
Hiyas A. Junio, Daniel A. Todd, Keivan A. Ettefagh, Brandie M. Ehrmann, Jeffrey S. Kavanaugh, Alexander H. Horswill, and Nadja B. Cech.
Journal of Chromatography B930, 7-12
PMID:23703543; doi: 10.1016/j.jchromb.2013


“Sarothrin from Alkanna orientalis is an antimicrobial agent and efflux pump inhibitor.”
Jessica R. Bame, Tyler N. Graf, Hiyas A. Junio, R. Owen Bussey, Scott A. Jarmusch, Tamam El-Elimat, Joseph O. Falkinham, Nicholas H. Oberlies, Richard A. Cech, and Nadja B. Cech.
Planta Medica79, 327-329
PMID:23468310; doi: 10.1055/s-0032-1328259

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“Quorum Quenching and Antimicrobial Activity of Goldenseal (Hydrastis canadensis) against Methicillin-Resistant Staphylococcus aureus (MRSA).”
Nadja B. Cech, Hiyas A. Junio, Laynez W. Ackermann, Jeffrey S. Kavanaugh, and Alexander H. Horswill.
Planta Medica, 2012, 78, 1556-1561


“Maplexins, new α-glucosidase inhibitors from red maple (Acer rubrum) stems.”
Chunpeng Wan, Tao Yuan, Vamsikrishna Kandhi, Nadja B. Cech, Mingyong Xie, and Navindra P. Seeram.
Bioorganic and Medicinal Chemistry Letters, 22, 567-600
PMID:22079755; doi: 10.1002/chin.201221211

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“Phenolic glycosides from sugar maple (Acer saccharum) bark.”
Tao Yuan, Chunpeng Wan, Antonio Gonzalez-Sarrias, Vamsikrishna Kandhi, Nadja B. Cech, and Navindra P. Seeram.
Journal of Natural Products, 742472-2476
PMID:22032697; doi: 10.1021/np200543z


“Synergy Directed Fractionation of Botanical Medicines: A Case Study with Goldenseal (Hydrastis canadensis).”
Hiyas A. Junio, Arlene A. Sy-Cordero, Keivan A. Ettefagh, Johnna T. Burns, Kathryn T. Micko, Tyler N. Graf, Scott J. Richter, Robert E. Cannon, Nicholas H. Oberlies, and Nadja B. Cech.
Journal of Natural Products, 74, 1621-1629
PMCID:PMC3142294; doi: 10.1021/np200336g


“Inhibition of H1N1 influenza A virus growth and induction of inflammatory mediators by the isoquinoline alkaloid berberine and extracts of goldenseal (Hydrastis canadensis).”
Chad E. Cecil, Jeanine M. Davis, Nadja B. Cech, and Scott M. Laster.
Intertational Immunopharmacology, 11, 1706-1714
PMID:21683808; doi: 10.1016/j.intimp.2011.06.002

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“Goldenseal (Hydrastis canadensis L.) extracts synergistically enhance the antibacterial activity of berberine via efflux pump inhibition.”
Keivan A. Ettefagh, Johnna T. Burns, Hiyas A. Junio, Glenn W. Kaatz, and Nadja B. Cech.
Planta Medica, 77, 835-840
PMCID: PMC3100400; doi: 10.1055/s-0030-1250606


“Echinacea and its alkylamides: effects on the influenza A-induced secretion of cytokines, chemokines, and PGE from RAW 264.7 macrophage-like cells.”
Nadja B. Cech, Vamsikrishna Kandhi, Jeanine M. Davis, Amy Hamilton, Dawn Eads, and Scott M. Laster.
Intertational Immunopharmacology, 10, 1268-1278
PMID: 21683808; doi: 10.1016/j.intimp.2010.07.009


“Selectivity in Electrospray Ionization Mass Spectrometry.”
Nadja B. Cech, and Christie G. Enke.
In: Electrospray and MALDI Mass Spectrometry, Ed. Cole, R.B. 2nd Edition, 49-73


“A Validated Liquid Chromatography/Electrospray Ionization-Mass Spectrometry (LC/ESI-MS) Method for Quantification of Spilanthol in Spilanthes acmella (L.) Murr.”
Stacy S. Bae, Brandie M. Ehrmann, Keivan A. Ettefagh, and Nadja B. Cech.
Phytochemical Analysis, 21, 438-443
PMID: 20310072; doi: 10.1002/pca.1215

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“Comparison of alkylamide yield in ethanolic extracts prepared from fresh versus dry Echinacea purpurea utilizing HPLC-ESI-MS”
Kevin Spelman, Matthew Wetschler, and Nadja B. Cech.
Journal of Pharmaceutical and Biomedical Analysis, 49, 1141-1149
PMCID: PMC2745817; doi: 10.1016/j.jpba.2009.02.011


“Role for PPAR <gamma> in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10- diynoic acid isobutylamide.”
Kevin Spelman, Katrina Liams-Hauser, Nadja B. Cech, Ethan Will Taylor, Nicholas Smirnoff, and Cynthia A. Wenner.
International Immunopharmacology, 91260-1264
PMID:19712756; doi: 10.1016/j.intimp.2009.08.009

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“Relative Importance of Basicity in the Gas Phase and in Solution for Determining Responsiveness to Electrospray Ionization Mass Spectrometry.”
Brandie M. Ehrmann, Trina Henriksen, and Nadja B. Cech.
Journal of the American Society for Mass Spectrometry, 19719-728
PMID: 18325781; doi: 10.1016/j.jasms.2008.01.003

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“Changes in floral color and anthocyanin production in Plantago lanceolata in response to temperature.”
Elizabeth A. Stiles, Nadja B. Cech, Stacy M. W. Dee, and Elizabeth P. Lacey.
Physiologia Plantarum, 129, 756-765


“Effects of Herbal Products and their constituents on Human Cytochrome P4502E1 Activity.”
Gregory M. Raner, Sean Cornelius, Kamalika Moulick, Yingqing Wang, Ashley M. Mortenson, Jonathan Hill, Connell Cunningham, and Nadja B. Cech.
Food and Chemical Toxicology, 45, 2359-2365
PMCID: PMC2955861; doi: 10.1016/j.fct.2007.06.012

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“Echinacea alkylamides inhibit interleukin-2 production by Jurkat human T cells.”
Masa Sasagawa, Nadja B. Cech, Dean E. Gray, Gary W. Elmer, and Cynthia A. Wenner.
International Immunopharmacology, 61214-1221
PMID:16714226; doi: 10.1016/j.intimp.2006.02.003


“Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: Production of novel metabolites and changes in immunomodulatory activity.”
Nadja B. Cech, Katrina Tutor, Bethany A. Doty, Kevin Spelman, Masa Sasagawa, Gregory M. Raner, and Cynthia A. Wenner.
Planta Medica, 751372-1377
PMID: 17054047; doi: 10.1055/s-2006-951718


“Electrospray ionization mass spectrometry: How and when it works.”
Nadja B. Cech, and Christie G. Enke.
Encyclopedia of Mass Spectrometry, 8171-180


“High performance liquid chromatography/electrospray ionization mass spectrometry for simultaneous analysis of alkylamides and caffeic acid derivatives from Echinacea purpurea extracts.”
Nadja B. Cech, Maqueita S. Eleazer, Lawresa T. Shoffner, Amanda C. Davis, Mark R. Crosswhite, and Ashley M. Mortenson.
Journal of Chromatography A, 1103219-228
PMID: 16298376; doi: 10.1016/j.chroma.2005.11.008

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“The relative influences of acidity and polarity on responsiveness of small organic molecules to analysis with negative ion electrospray ionization mass spectrometry (ESI-MS).”
Trina Henriksen, Renee K. Juhler, Bo Svensmark, and Nadja B. Cech.
Journal of the American Society for Mass Spectrometry, 16, 446-455
PMID: 15792713; doi: 10.1016/j.jasms.2004.11.021

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“Practical implications of some recent studies in electrospray ionization fundamentals.”
Nadja B. Cech, and Christie G. Enke.
Mass Spectrometry Reviews, 20362-287
PMID: 11997944; doi: 10.1002/mas.10008

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“Electrospray ionization detection of an inherently nonresponsive epoxide by peptide binding.”
Nadja B. Cech, Jennifer R. Krone, and Christie G. Enke.
Rapid Communications in Mass Spectrometry, 151040-1044
PMID:11404839; doi: 10.1002/rcm.337


“Predicting electrospray response from chromatographic retention time.”
Nadja B. Cech, Jennifer R. Krone, and Christie G. Enke.
Analytical Chemistry, 73, 208-213
PMID: 11199967; doi: 10.1021/ac0006019


“The effect of affinity for charged droplet surfaces on the fraction of analyte charged in the electrospray process.”
Nadja B. Cech, and Christie G. Enke.
Analytical Chemistry, 73, 4632-4639
PMID:11605841; doi: 10.1021/ac001267j

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“Relating electrospray ionization response to non-polar character of small peptides.”
Nadja B. Cech, and Christie G. Enke.
Analytical Chemistry, 72, 2717-2723
PMID:10905298; doi: 10.1021/ac9914869

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“Electrospray ionization mass spectrometric analysis of blood for differentiation of species.”
Edgard O. Espinoza, Nadja B. Cech, Kathy M. Gordon, Jessica Ekhoff, and Mark A. Kirms.
Analytical Biochemistry, 268, 252-261
PMID:10075815; doi: 10.1006/abio.1998.3048

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