Spotlight and Highlights Published

Congrats to Sanath for writing up a spotlight for Angewedte Chemie on the recently published study on the biosynthesis of strychnine by the O’Connor group.

Kandy, S. K., and Chekan, J. R. (2022) Biosynthesis of the Plant-Produced Toxin Strychnine Elucidated (Highlight). Angew. Chem. Int. Ed Engl. 61, e202212301 (doi: 10.1002/anie.202212301)



As part of the 40th anniversary of Trends in Biotechnology, we were happy to spotlight a seminal achievement in the industrial production of an essential natural product. In 2013, Paddon et. al. achieved the the production of 25 g/L artemisinic acid in yeast coupled with a synthetic approach to yield the antimalarial drug artemisinin.
Smith, A. B., and Chekan, J. R. (2022) Engineering yeast for industrial-level production of the antimalarial drug artemisinin (Spotlight). Trends Biotechnol.  (doi: 10.1016/j.tibtech.2022.12.007)



20 Dec 2022