News & Events

Tian Li

Posted on November 4, 2020


Date - November 4, 2020
1:00 pm - 2:00 pm


Title: The Recent Development of Palladium (I) Catalyzed Cross-Coupling Reactions


Carbon-carbon bond formation has been, and continues to be, of interest to organic community. During the past sixty years, reactions like the Wurtz reaction, Pd-cross coupling, and Photoredox cross coupling have allowed chemists to make the crucial carbon-carbon bonds needed to form complex molecules. Mechanistically, due to the side reactions associated with b-hydride elimination and side reactions the selective formation of the desired carbon-carbon bonds has been a challenge. Researchers reported series of work using air-stable Palladium (I) dimer. Using these unique catalysts to trigger rapid C-C couplings at room temperature in a modular and selective fashion of aromatic C-Br, C-OTf and C-Cl bonds in poly(pseudo)halogenated arenes , displaying superior activity over traditional palladium (0) and palladium (II) catalysts.