News

PTC Paper Published in Chem

Out now in Chem , we collaborate with the Piel to discover a prenyltransferase+terpene cyclase fusion enzyme that modifies tryptophans residues in RiPPs to yield complex steroid-like scaffolds! Congrats to Sanath for co-leading this work!

 

 

Hubrich, F., Kandy, S. K., Chepkirui, C., Padhi, C., Mordhorst, S., Moosmann, P., Zhu, T., Gugger, M., Chekan, J. R.^# and Piel, J.^# (2024) Ribosomal peptides with polycyclic isoprenoid moieties. Chem. (doi: 10.1016/j.chempr.2024.07.026)