Publications
2024
| 275 |
“Evolutionary Origin and Population Diversity of a Cryptic Hybrid Pathogen” Jacob L Steenwyk, Sonja Knowles, Rafael W Bastos, Nature Communications, 2024, 15, 8412 PMID: 39333551; PMCID: PMC11436853; doi: 10.1038/s41467-024-52639-1 |
| 274 |
“Phylogenomics Reveals Extensive Misidentification of Fungal Strains from the Genus Aspergillus“ Jacob L. Steenwyk, Charu Balamurugan, Huzefa A. Raja, Microbiology Spectrum, 2024, 12, e0398023 PMID: 38445873; PMCID: PMC10986620; doi: 10.1128/spectrum.03980-23 |
| 273 |
“Bioactivity‑Driven Fungal Metabologenomics Identifies Antiproliferative Stemphone Analogs and Their Biosynthetic Gene Cluster” Navid J. Ayon, Cody E. Earp, Raveena Gupta, Fatma A. Butun, Metabolomics, 2024, 20:90 PMID: 39095664; PMCID: PMC11296971; doi: 10.1007/s11306-024-02153-8 |
| 272 |
“Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice” Victoria O. Oyanna, Baron J. Bechtold, Katherine D. Lynch, M. Ridge Call, Tyler N. Graf, Nicholas H. Oberlies, and John D. Clarke Pharmaceutical Research, 2024, 41, 557-566. PMID: 38302834; PMCID: PMC10939713; doi: 10.1007/s11095-024-03662-w |
| 271 |
“Wheldone Revisited: Structure Revision Via DFT-GIAO Chemical Shift Calculations, 1,1-HD-ADEQUATE NMR Spectroscopy, and X‑ray Crystallography Studies” Manuel Rangel-Grimaldo, Cody E. Earp, Huzefa A. Raja, Journal of Natural Products, 2024, 87, 2095-2100. PMID: 39039966; PMCID: PMC11348420; doi: 10.1021/acs.jnatprod.4c00649 |
| 270 |
“Strain Heterogeneity in a Non-Pathogenic Fungus Highlights Factors Contributing to Virulence” David C. Rinker, Thomas J. C. Sauters, Karin Steffen, Communications Biology, 2024, 7, 1082 PMID: 39232082; PMCID: PMC11374809; doi: doi.org/10.1038/s42003-024-06756-8 |
| 269 |
“Verticillins: Fungal Epipolythiodioxopiperazine Alkaloids with Chemotherapeutic Potential” Herma C. Pierre, Chiraz Soumia M. Amrine, Natural Product Reports, 2024. PMID: 38629495; doi: 10.1039/d3np00068k |
| 268 |
“Neosetophomone B Induces Apoptosis in Multiple Myeloma Cells via Targeting of AKT/SKP2 Signaling Pathway” Shilpa Kuttikrishnan, Fareed Ahmad, Jericha M. Mateo, Kirti S. Prabhu, Tamam El‐Elimat, Nicholas H. Oberlies, Cedric J. Pearce, Ammira S. Alshabeeb Akil, Ajaz A. Bhat, Feras Q. Alali, and Shahab Uddin Cell Biology International, 2024, 48, 190-200. PMID: 37885161; PMCID: PMC10952688; doi: 10.1002/cbin.12101 |
| 267 |
“Rifampin- and Silymarin-Mediated Pharmacokinetic Interactions of Exogenous and Endogenous Substrates in a Transgenic OATP1B Mouse Model” Baron J. Bechtold, Katherine D. Lynch, Molecular Pharmaceutics, 2024, 21, 2284-2297. PMID: 38529622; PMCID: PMC11073900; doi: 10.1021/acs.molpharmaceut.3c01088 |
| 266 |
“Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice” Baron J. Bechtold, Katherine D. Lynch, Victoria O. Oyanna, M. Ridge Call, Laura A. White, Tyler N. Graf, Nicholas H. Oberlies, and John D. Clarke Drug Metabolism and Disposition, 2024, 52, 355-367. PMID: 38485280; PMCID: PMC11023818; doi: 10.1124/dmd.123.001607 |
| 265 |
“Semisynthesis, Characterization, and Biological Evaluation of Fluorinated Analogues of the Spirobisnaphthalene, Diepoxin-η” Hadi Pourhadi, Tamam El-Elimat, Manuel Rangel-Grimaldo, Tetrahedron Letters, 2024, 134, 154857 PMID: 38328000; PMCID: PMC10846677; doi: 10.1016/j.tetlet.2023.154857 |
| 264 |
“Exploring the in vivo Anti-Cancer Potential of Neosetophomone B in Leukemic Cells Using a Zebrafish Xenograft Model” Shilpa Kuttikrishnan, Maram Hasan, Experimental Cell Research, 2024, 435, 113907 PMID: 38184222; doi: 10.1016/j.yexcr.2023.113907 |
| 263 |
“Semisynthetic Derivatives of the Fungal Metabolite Eupenifeldin via Targeting the Tropolone Hydroxy Groups” Zeinab Y. Al Subeh, Herma C. Pierre, Ross H. Bockbrader, Bioorganic & Medicinal Chemistry Letters, 2024, 110, 129875 PMID: 38964520; PMCID: PMC11369961; doi: 10.1016/j.bmcl.2024.129875 |
Charu Balamurugan, David Rinker, Matthew E Mead, Christopher D Roberts, Huzefa A Raja, Yuanning Li, Ana Cristina Colabardini, Patrícia Alves de Castro, Thaila Fernanda Dos Reis, Adiyantara Gumilang, María Almagro-Molto, Alexandre Alanio, Dea Garcia-Hermoso, Endrews Delbaje, Laís Pontes, Camila Figueiredo Pinzan, Angélica Zaninelli Schreiber, David Canóvas, Rafael Sanchez Luperini, Katrien Lagrou, Egídio Torrado, Fernando Rodrigues, Nicholas H Oberlies, Xiaofan Zhou, Gustavo H Goldman, and Antonis Rokas
Carla Gonçalves, Ningxiao Li, Frank Martin, Judith Berman, Nicholas H. Oberlies, John G. Gibbons, Gustavo H. Goldman, David M. Geiser, Jos Houbraken, David S. Hibbett, and Antonis Rokas
Ashley E. Clements, Alexa G. Lee, David Dainko, Matthew T. Robey, Manead Khin, Lina Mardiana, Alexandra Longcake, Manuel Rangel‑Grimaldo, Michael J. Hall, Michael R. Probert, Joanna E. Burdette, Nancy P. Keller, Huzefa A. Raja, Nicholas H. Oberlies, Neil L. Kelleher, and Lindsay K. Caesar
Jared S. Wood, Lina Mardiana, Kin Lok Ho, Alexandra Longcake, R. Thomas Williamson, Lukáš Palatinus, Michael J. Hall, Michael R. Probert, and Nicholas H. Oberlies
Adiyantara Gumilang, Huzefa A. Raja, Manuel Rangel-Grimaldo, Camila Figueiredo Pinzan, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Endrews Delbaje, Jos Houbraken, Gustavo H. Goldman, Nicholas H. Oberlies, and Antonis Rokas
Michael G. Doyle, Amrita Salvi, Huzefa A. Raja, Jonathan R. Chekan, Andrew C. Huntsman, James R. Fuchs, Kebin Liu, Joanna E. Burdette, Cedric J. Pearce, and Nicholas H. Oberlies
Victoria O. Oyanna, M. Ridge Call, Tyler N. Graf,
Tyler N. Graf, Joseph O. Falkinham III, Manead Khin, Joanna E. Burdette, Nathan Mirtallo Ezzone, Jonathan G. Jeyaraj, Esperanza Carcache de Blanco, Cedric J. Pearce, and Nicholas H. Oberlies
Kirti S. Prabhu, Tamam El-Elimat,
Robert J. Tokarski II, Amanda C. Maldonado, Monica A. Haughan, Manuel E. Rangel-Grimaldo, Cedric J. Pearce, Joanna E. Burdette, James R. Fuchs, and Nicholas H. Oberlies2023
| 262 |
“Radiolabeled Biodistribution of Expansile Nanoparticles: Intraperitoneal Administration Results in Tumor Specific Accumulation” Aaron H. Colby, Jack Kirsch, Amit N. Patwa, Rong Liu, ACS Nano, 2023, 17, 2212-2221. PMID: 36701244; PMCID: PMC9933882; doi: 10.1021/acsnano.2c08451
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| 261 |
“Clinical Assessment of the Drug Interaction Potential of the Psychotropic Natural Product Kratom.” Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Clinical Pharmacology & Therapeutics, 2023, 113, 1315-1325. PMID: 36924284; PMCID: PMC10198846; doi: 10.1002/cpt.2891 |
| 260 |
“Exploration of Verticillins in High-Grade Serous Ovarian Cancer and Evaluation of Multiple Formulations in Preclinical in Vitro and in Vivo Models.” Elizabeth N. Kaweesa, Jaqueline M. Bazioli, Molecular Pharmaceutics, 2023, 20, 3049-3059. PMID: 37155928; PMCID: PMC10405366; doi: 10.1021/acs.molpharmaceut.3c00069 |
| 259 |
“Trachymyrmex septentrionalis Ants Promote Fungus Garden Hygiene Using Trichoderma-Derived Metabolite Cues.” Kathleen E. Kyle, Sara P. Puckett, Andrés Mauricio Proceedings of the National Academy of Sciences, 2023, 120, e2219373120. PMID: 37319116; PMCID: PMC10288546; doi: 10.1073/pnas.2219373120 |
| 258 |
“Evaluating the Antioxidant Properties of the Ancient-Crop Tef (Eragrostis tef) Grain Extracts in THP-1 Monocytes.” Christopher J. Cotter, Allison J. Wright, Antioxidants, 2023, 12, 1561 PMID: 37627557; PMCID: PMC10451390; doi: 10.3390/antiox12081561 |
| 257 |
“Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models.” Amanda C. Maldonado, Monica A. Haughan, Journal of Natural Products, 2023, 86, 2102-2110. PMID: 37643353; PMCID: PMC10792992; doi: 10.1021/acs.jnatprod.3c00186 |
| 256 |
“In Vitro Evaluation of Neosetophomone B Inducing Apoptosis in Cutaneous T Cell Lymphoma by Targeting the FOXM1 Signaling Pathway.” Shilpa Kuttikrishnan, Tariq Masoodi, Fareed Ahmad, Journal of Dermatological Science, 2023, 112, 83-91. PMID: 37865581; doi: 10.1016/j.jdermsci.2023.10.001 |
| 255 |
“Neosetophomone B Induces Apoptosis in Multiple Myeloma Cells Via Targeting of AKT/SKP2 Signaling Pathway.” Shilpa Kuttikrishnan, Fareed Ahmad, Cell Biology International, 2024, 48, 190-200. PMID: 37885161; doi: 10.1002/cbin.12101 |
| 254 |
“What Was Old Is New Again: Phenotypic Screening of a Unique Fungal Library Yields Pyridoxatin, a Promising Lead against Extensively Resistant Acinetobacter Baumannii (Ab5075).” Heather L. Winter, Laura Flores-Bocanegra, Phytochemistry Letters, 2023, 55, 88-96. PMID: 37252254; PMCID: PMC10210987; doi: 10.1016/j.phytol.2023.04.002 |
| 253 |
“Translating Kratom-Drug Interactions: From Bedside to Bench and Back.” Rakshit S. Tanna, Nadja B. Cech, Nicholas H. Oberlies, Drug Metabolism and Disposition, 2023, 51, 923. PMID: 37286363; PMCID: PMC10353077; doi: 10.1124/dmd.122.001005 |
| 252 |
“Sheptide A: An Antimalarial Cyclic Pentapeptide from a Fungal Strain in the Herpotrichiellaceae.” Robert A. Shepherd, Cody E. Earp, Kristof B. Cank, The Journal of Antibiotics, 2023, 76, 642-649. PMID: 37731043; PMCID: PMC10602849; doi: 10.1038/s41429-023-00655-6 |
| 251 |
“Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice.” Victoria O. Oyanna, Kenisha Y. Garcia-Torres, Drug Metabolism and Disposition, 2023, 51, 1483. PMID: 37562957; PMCID: PMC10586506; doi: 10.1124/dmd.123.001360 |
| 250 |
“Correlative Metabologenomics of 110 Fungi Reveals Metabolite–Gene Cluster Pairs.” Lindsay K. Caesar, Fatma A. Butun, Matthew T. Robey, Nature Chemical Biology, 2023, 19, 846-854. PMID: 36879060; PMCID: PMC10313767; doi: 10.1038/s41589-023-01276-8 |
| 249 |
“Embellicines C-E: Macrocyclic Alkaloids with a Cyclopenta[b]fluorene Ring System from the Fungus Sarocladium sp.” Zeinab Y. Al Subeh, Laura Flores-Bocanegra, Journal of Natural Products, 2023, 86, 596-603. PMID: 36884371; PMCID: PMC10043936; doi: 10.1021/acs.jnatprod.2c01048 |
| 248 |
“From Plant to Cancer Drug: Lessons Learned from the Discovery of Taxol.” Nadja B. Cech, and Nicholas H. Oberlies Natural Product Reports, 2023, 40, 1153-1157. PMID: 37449327; PMCID: PMC10354831; doi: 10.1039/d3np00017f |
Beth Hollister, William McCulloch, Joanna E. Burdette, Cedric J. Pearce, Nicholas H. Oberlies, Yolonda L. Colson, Kebin Liu, and Mark W. Grinstaff
Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, and Mary F. Paine
Herma C. Pierre, Daniel D. Lantvit, Samuel K. Kulp, Kasey L. Hill, Mitch A. Phelps, Christopher C. Coss, James R. Fuchs, Cedric J. Pearce, Nicholas H. Oberlies, and Joanna E. Burdette
Caraballo-Rodríguez, José Rivera-Chávez, Robert M. Samples, Cody E. Earp, Huzefa A. Raja, Cedric J. Pearce, Madeleine Ernst, Justin J. J. van der Hooft, Madison E. Adams, Nicholas H. Oberlies, Pieter C. Dorrestein, Jonathan L. Klassen, and Marcy J. Balunas
Anastasia V. Romanov, Tyler N. Graf, Eric D. Whisnant, Laura Flores-Bocanegra, Megan S. Doldron, Nicholas H. Oberlies, Zhenquan Jia, and Ayalew Ligaba-Osena
Manead Khin, Julia Ekiert, Ziwei Zhang, Daniel Lantvit, Zeinab Y. Al Subeh, Herma C. Pierre, Maryna Salkovski, Tal Hirschhorn, Yu Gao, Cedric J. Pearce, Brent R. Stockwell, Leslie N. Aldrich, Nicholas H. Oberlies, and Joanna E. Burdette
Gulab Sher, Kirti S. Prabhu, Jericha M. Mateo, Joerg Buddenkotte, Tamam El-Elimat, Nicholas H. Oberlies, Cedric J. Pearce, Ajaz A. Bhat, Feras Q. Alali, Martin Steinhoff, and Shahab Uddin
Jericha M. Mateo, Kirti S. Prabhu, Tamam El-Elimat, Nicholas H. Oberlies, Cedric J. Pearce, Ammira S. Alshabeeb Akil, Ajaz A. Bhat, Feras Q. Alali, and Shahab Uddin
Kristóf B. Cank, William J. Crandall, Fridah C. Rotich, Madeline N. Tillman, Daniel A. Todd, Tyler N. Graf, Huzefa A. Raja, Cedric J. Pearce, Nicholas H. Oberlies, and Nadja B. Cech
Allan E. Rettie, Kenneth E. Thummel, and Mary F. Paine
Huzefa A. Raja, Joanna Burdette, Steven P. Maher, Adriana A. Marin, Anthony A. Ruberto, Sarah Lee Mai, Blaise A. Darveaux, Dennis E. Kyle, Cedric J. Pearce, and Nicholas H. Oberlies
Baron J. Bechtold, Katherine D. Lynch, Call M. Ridge, Miklós Horváth, Preston K. Manwill, Tyler N. Graf, Nadja B. Cech, Nicholas H. Oberlies, Mary F. Paine, and John D. Clarke
Navid J. Ayon, Raveena Gupta, David Dainko, Jin Woo Bok, Grant Nickles, Robert J. Stankey, Don Johnson, David Mead, Kristof B. Cank, Cody E. Earp, Huzefa A. Raja, Nicholas H. Oberlies, Nancy P. Keller, and Neil L. Kelleher
Huzefa A. Raja, Joanna E. Burdette, Cedric J. Pearce, and Nicholas H. Oberlies
2022
| 247 |
“Editorial for the Special Issue Dedicated to Prof. A. Douglas Kinghorn.” Nicholas H. Oberlies and Mario Figueroa Planta Med, 2022, 88, 696-697. PMID: 35915888; doi: 10.1055/a-1882-1011 |
| 246 |
“Homoisoflavonoids from the Bulbs of Bellevalia longipes and an Assessment of Their Potential Cytotoxic Activity.” Tamam El-Elimat, Reema Al-Qiam, Joanna E. Burdette, Phytochemistry, 2022, 203, 113343. PMID: 35963294; PMCID: PMC9795560; doi: 10.1016/j.phytochem.2022.113343 |
| 245 |
“Lipid Nanoparticle Delivery of Fas Plasmid Restores Fas Expression to Suppress Melanoma Growth in Vivo.” Zeinab Y. Al Subeh, Dakota B. Poschel, Priscilla S. Redd, ACS Nano, 2022, 16, 12695-12710. PMID: 35939651; PMCID: PMC9721370; doi: 10.1021/acsnano.2c04420 |
| 244 |
“H3K9ME3 Represses G6PD Expression to Suppress the Pentose Phosphate Pathway and ROS Production to Promote Human Mesothelioma Growth.” Chunwan Lu, Dafeng Yang, John D. Klement, Oncogene, 2022, 41, 2651-2662. PMID: 35351997; PMCID: PMC9058223; doi: 10.1038/s41388-022-02283-0 |
| 243 |
“Discovery of Anticancer Agents of Diverse Natural Origin.” Leslie N. Aldrich, Joanna E. Burdette, Journal of Natural Products, 2022, 85, 702-719. PMID: 35213158; PMCID: PMC9034850; doi: 10.1021/acs.jnatprod.2c00036 |
| 242 |
“Semisynthesis of Hypothemycin Analogues Targeting the C8–C9 Diol.” Zeinab Y. Al Subeh, Tian Li, Abraham Ustoyev, Journal of Natural Products, 2022, 85, 2018-2025. PMID: 35834411; PMCID: PMC9677340; doi: 10.1021/acs.jnatprod.2c00434 |
| 241 |
“Genomic and Phenotypic Trait Variation of the Opportunistic Human Pathogen Aspergillus flavus and Its Close Relatives.” E. Anne Hatmaker, Manuel Rangel-Grimaldo, Microbiology Spectrum, 2022, 10, e03069-03022. PMID: 36318036; PMCID: PMC9769809; doi: 10.1128/spectrum.03069-22 |
| 240 |
“Bioinformatics Analysis Reveals FOXM1/BUB1B Signaling Pathway as a Key Target of Neosetophomone B in Human Leukemic Cells: A Gene Network-Based Microarray Analysis.” Shilpa Kuttikrishnan, Tariq Masoodi, Gulab Sher, Frontiers in Oncology, 2022, 12, PMID: 35847923; PMCID: PMC9283897; doi: 10.3389/fonc.2022.929996 |
| 239 |
“Anticancer Activity of Neosetophomone B by Targeting AKT/SKP2/MTH1 Axis in Leukemic Cells.”
Shilpa Kuttikrishnan, Ajaz A. Bhat, Jericha M. Mateo, Biochemical and Biophysical Research Communications, 2022, 601, 59-64. PMID: 35228122; doi: 10.1016/j.bbrc.2022.02.071 |
| 238 |
“Clinical Pharmacokinetic Assessment of Kratom (Mitragyna speciosa), a Botanical Product with Opioid-Like Effects, in Healthy Adult Participants.” Rakshit S. Tanna, James T. Nguyen, Deena L. Hadi, Pharmaceutics, 2022, 14, 620. PMID: 35335999; PMCID: PMC8950611; doi: 10.3390/pharmaceutics14030620 |
| 237 |
“Metabolomics-Guided Comparison of Pollen and Microalgae-Based Artificial Diets in Honey Bees.” Vincent A. Ricigliano, Kristof B. Cank, Daniel A. Todd, Journal of Agricultural and Food Chemistry, 2022, 70, 9790-9801. PMID: 35881882; PMCID: PMC9372997; doi: 10.1021/acs.jafc.2c02583 |
| 236 |
“Genomic Characterization of Parengyodontium Torokii sp. nov., a Biofilm-Forming Fungus Isolated from Mars 2020 Assembly Facility.” Ceth W. Parker, Marcus D. Teixeira, Nitin K. Singh, Journal of Fungi, 2022, 8, 66. PMID: 35050006; PMCID: PMC8778116; doi: 10.3390/jof8010066 |
| 235 |
“Kratom (Mitragyna speciosa) Validation: Quantitative Analysis of Indole and Oxindole Alkaloids Reveals Chemotypes of Plants and Products.” Preston K. Manwill, Laura Flores-Bocanegra, Manead Khin, Planta Medica, 2022, 88, 838-857. PMID: 35468648; PMCID: PMC9343938; doi: 10.1055/a-1795-5876 |
| 234 |
“G6PD Functions as a Metabolic Checkpoint to Regulate Granzyme B Expression in Tumor-Specific Cytotoxic T Lymphocytes.” Chunwan Lu, Dafeng Yang, John D. Klement, Journal for ImmunoTherapy of Cancer, 2022, 10, e003543. PMID: 35017152; PMCID: PMC8753452; doi: 10.1136/jitc-2021-003543 |
| 233 |
“Natural Resorcylic Acid Lactones: A Chemical Biology Approach for Anticancer Activity.” Shilpa Kuttikrishnan, Kirti S. Prabhu, Ahmed H. Al Sharie, Drug Discovery Today, 2022, 27, 547-557. PMID: 34655796; doi: 10.1016/j.drudis.2021.10.001 |
| 232 |
“Fungal–Fungal Co-Culture: A Primer for Generating Chemical Diversity.” Sonja L. Knowles, Huzefa A. Raja, Christopher D. Roberts, Natural Product Reports, 2022, 39, 1557-1573. PMID: 35137758; PMCID: PMC9384855; doi: 10.1039/d1np00070e |
| 231 |
“Dereplication of Fungal Metabolites by Nmr-Based Compound Networking Using MADByTE.” Laura Flores-Bocanegra, Zeinab Y. Al Subeh, Joseph M. Egan, Journal of Natural Products, 2022, 85, 614-624. PMID: 35020372; PMCID: PMC8957573; doi: 10.1021/acs.jnatprod.1c00841 |
| 230 |
“Regulation of Gliotoxin Biosynthesis and Protection in Aspergillus Species.” Patrícia Alves de Castro, Ana Cristina Colabardini,
PLOS Genetics, 2022, 18, e1009965. PMID: 35041649; PMCID: PMC8797188; doi: 10.1371/journal.pgen.1009965 |
| 229 |
“Polychlorinated Cyclopentenes from a Marine Derived Periconia sp. (Strain G1144).” Kristóf B. Cank, Robert A. Shepherd, Sonja L. Knowles, Phytochemistry, 2022, 199, 113200. PMID: 35421431; PMCID: PMC9173697; doi: 10.1016/j.phytochem.2022.113200 |
| 228 |
“Structural Diversity of Perylenequinones Is Driven by Their Redox Behavior.” Zeinab Y. Al Subeh, Amy L. Waldbusser, Huzefa A. Raja,
The Journal of Organic Chemistry, 2022, 87, 2697-2710.
PMID: 35077640; PMCID: PMC8898278; doi: 10.1021/acs.joc.1c02639 |
Ahmed H. Al Sharie, Mohammad Al-Gharaibeh, and Nicholas H. Oberlies
John D. Klement, Alyssa D. Merting, Dafeng Yang, Megh Mehta, Huidong Shi, Yolonda L. Colson, Nicholas H. Oberlies, Cedric J. Pearce, Aaron H. Colby, Mark W. Grinstaff, and Kebin Liu
Yolonda L. Colson, Nicholas H. Oberlies, Cedric J. Pearce, Aaron H. Colby, Mark W. Grinstaff, Zhuoqi Liu, Huidong Shi, Han-Fei Ding, and Kebin Liu
Esperanza Carcache de Blanco, Christopher C. Coss, Alessandra S. Eustaquio, James R. Fuchs, A. Douglas Kinghorn, Amanda MacFarlane, Brittney K. Mize, Nicholas H. Oberlies, Jimmy Orjala, Cedric J. Pearce, Mitch A. Phelps, Liva Harinantenaina Rakotondraibe, Yulin Ren, Djaja Doel Soejarto, Brent R. Stockwell, Jack C. Yalowich, and Xiaoli Zhang
Jennifer C. Obike, Philip M. West, Manead Khin, Joanna E. Burdette, Cedric J. Pearce, Nicholas H. Oberlies, and Mitchell P. Croatt
Huzefa A. Raja, Hadi Pourhadi, Sonja L. Knowles, Kevin Fuller, Emily M. Adams, Jorge D. Lightfoot, Rafael W. Bastos, Gustavo H. Goldman, Nicholas H. Oberlies, and Antonis Rokas
Ajaz A. Bhat, Kalyani Patil, Tamam El-Elimat, Nicholas H. Oberlies, Cedric J. Pearce, Mohmmad Haris, Aamir Ahmad, Feras Q. Alali, and Shahab Uddin
Fareed Ahmad, Feras Q. Alali, Tamam El-Elimat, Nicholas H. Oberlies, Cedric J. Pearce, and Shahab Uddin
Preston K. Manwill, Laura Flores-Bocanegra, Matthew E. Layton, John R. White, Nadja B. Cech, Nicholas H. Oberlies, Allan E. Rettie, Kenneth E. Thummel, and Mary F. Paine
Sonja L. Knowles, and Nicholas H. Oberlies
Huzefa A. Raja, Kristof B. Cank, Giada Spigolon, Nicholas H. Oberlies, Bridget M. Barker, Jason E. Stajich, Christopher E. Mason, and Kasthuri Venkateswaran
Huzefa A. Raja, Nadja B. Cech, Nicholas H. Oberlies, and Daniel A. Todd
Yolonda L. Colson, Nicholas H. Oberlies, Cedric J. Pearce, Aaron H. Colby, Mark W. Grinstaff, Han-Fei Ding, Huidong Shi, and Kebin Liu
Yazan O. Al Zu’bi, Feras Q. Alali, Nicholas H. Oberlies, Aamir Ahmad, Tamam El-Elimat, and Shahab Uddin
and Nicholas H. Oberlies
Tamam El-Elimat, Huzefa A. Raja, Joanna E. Burdette, Cedric J. Pearce, Roger G. Linington, and Nicholas H. Oberlies
Maísa Moraes, Maria Augusta Crivelente Horta, Sonja L. Knowles, Huzefa A. Raja, Nicholas H. Oberlies, Yasuji Koyama, Masahiro Ogawa, Katsuya Gomi, Jacob L. Steenwyk, Antonis Rokas, Relber A. Gonçales, Cláudio Duarte-Oliveira, Agostinho Carvalho, Laure N. A. Ries, and Gustavo H. Goldman
Manuel Rangel-Grimaldo, Huzefa A. Raja, Zoie L. Bunch, Nadja B. Cech, Christopher A. Rice, Dennis E. Kyle, Joseph O. Falkinham, Joanna E. Burdette, and Nicholas H. Oberlies
Cedric J. Pearce, Kin Lok Ho, Michael J. Hall, Michael R. Probert, Nicholas H. Oberlies, and Shabnam Hematian2021
| 227 |
“Cytotoxic and Antimicrobial Drimane Meroterpenoids from a Fungus of the Stictidaceae (Ostropales, Ascomycota).”Laura Flores-Bocanegra, Mario Augustinović, Huzefa A. Raja, Steven J. Kurina, Tetrahedron Letters, 2021, 68, 152896. PMID: 35431352; PMCID: PMC9012486; doi: 10.1016/j.tetlet.2021.152896 |
| 226 |
“Genomic and Phenotypic Analysis of COVID-19-Associated Pulmonary Aspergillosis Isolates of Aspergillus fumigatus.”L. Steenwyk Jacob, E. Mead Matthew, Alves de Castro Patrícia, Clara Valero, Microbiology Spectrum, 9, e00010-00021. PMID: 34106569; PMCID: PMC8552514; doi: 10.1128/Spectrum.00010-21 |
| 225 |
“Occasional Comment: Fungal Identification to Species-Level Can Be Challenging.”Huzefa A. Raja, Nicholas H. Oberlies, and Marc Stadler Phytochemistry, 2021, 190, 112855. PMID: 34273757; doi: 10.1016/j.phytochem.2021.112855 |
| 224 |
“Hepatic Organic Anion Transporting Polypeptides Mediate Disposition of Milk Thistle Flavonolignans and Pharmacokinetic Silymarin-Drug Interactions.”Katherine D. Lynch, Michelle L. Montonye, Dan-Dan Tian, Tarana Arman, Victoria O. Oyanna, Baron J. Bechtold, Tyler N. Graf, Nicholas H. Oberlies, Mary F. Paine, and John D. Clarke Phytotherapy Research, 2021, 35, 3286-3297. PMID: 33587330; PMCID: PMC8217340; doi: 10.1002/ptr.7049 |
| 223 |
“Polyphasic Approach Utilized for the Identification of Two New Toxigenic Members of Penicillium Section Exilicaulis, P. krskae and P. silybi spp. Nov.”Roman Labuda, Markus Bacher, Thomas Rosenau, Journal of Fungi, 2021, 7, 557. PMID: 34356936; PMCID: PMC8307998; doi: 10.3390/jof7070557 |
| 222 |
“Freshwater Fungi as a Source of Chemical Diversity: A Review.”Tamam El-Elimat, Huzefa A. Raja, Mario Figueroa, Journal of Natural Products, 2021, 84, 898-916. PMID: 33662206; PMCID: PMC8127292; doi: 10.1021/acs.jnatprod.0c01340 |
| 221 |
“Coumarins, Dihydroisocoumarins, a Dibenzo-α-Pyrone, a Meroterpenoid, and a Merodrimane from Talaromyces amestolkiae.”Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Tetrahedron Letters, 2021, 72, 153067. PMID: 34421136; PMCID: PMC8378670; doi: 10.1016/j.tetlet.2021.153067 |
| 220 |
“Pilot-Scale Production of Expansile Nanoparticles: Practical Methods for Clinical Scale-Up.”Aaron H. Colby, Rong Liu, Robert P. Doyle, Alyssa Merting, Heng Zhang, Natasha Savage, Ngoc-Quynh Chu, Beth A. Hollister, William McCulloch, Joanna E. Burdette, Cedric J. Pearce, Kebin Liu, Nicholas H. Oberlies, Yolonda L. Colson, and Mark W. Grinstaff Journal of Controlled Release, 2021, 337, 144-154. PMID: 34280414; PMCID: PMC8489532; doi: 10.1016/j.jconrel.2021.07.012 |
| 219 |
“Droplet Probe: A Non-Destructive Residue Analysis of Wari Ceramics from the Imperial Heartland.”Kristóf B. Cank, Joshua M. Henkin, Anita G. Cook, Journal of Archaeological Science, 2021, 134, 105468. |
| 218 |
“Media and Strain Studies for the Scaled Production of Cis-Enone Resorcylic Acid Lactones as Feedstocks for Semisynthesis.”Zeinab Y. Al Subeh, Huzefa A. Raja, Jennifer C. Obike, The Journal of Antibiotics, 2021, 74, 496-507. PMID: 34155352; PMCID: PMC8313427; doi: 10.1038/s41429-021-00432-3 |
| 217 |
“Three Diketomorpholines from a Penicillium sp. (Strain G1071).”Zeinab Y. Al Subeh, Huzefa A. Raja, Joanna E. Burdette, Phytochemistry, 2021, 189, 112830 PMID: 34157637; PMCID: PMC8292221; doi: 10.1016/j.phytochem.2021.112830 |
| 216 |
“Semisynthetic Derivatives of the Verticillin Class of Natural Products through Acylation of the C11 Hydroxy Group.”Chiraz Soumia M. Amrine, Andrew C. Huntsman, Michael G. Doyle, Joanna E. Burdette, ACS Medicinal Chemistry Letters, 2021, 12, 625-630. PMID: 33859802; PMCID: PMC8040035; doi: 10.1021/acsmedchemlett.1c00024 |
| 215 |
“Opportunities and Limitations for Assigning Relative Configurations of Antibacterial Bislactones Using GIAO NMR Shift Calculations.”Sonja L. Knowles, Christopher D. Roberts, Mario Augustinović, Laura Flores-Bocanegra, Journal of Natural Products, 2021, 84, 1254-1260. PMID: 33764773; PMCID: PMC8108483; doi: 10.1021/acs.jnatprod.0c01309 |
| 214 |
“Thielavins: Tuned Biosynthesis and LR-HSQMBC for Structure Elucidation.”Zeinab Y. Al Subeh, Huzefa A. Raja, Amanda Maldonado, The Journal of Antibiotics, 2021, 74, 300-306. PMID: 33495550; PMCID: PMC8084880; doi: 10.1038/s41429-021-00405-6 |
| 213 |
“Delivery of Eupenifeldin via Polymer-Coated Surgical Buttresses Prevents Local Lung Cancer Recurrence.”Zeinab Y. Al Subeh, Ngoc-Quynh Chu, Jeremy T. Korunes-Miller, Lillian L. Tsai, Journal of Controlled Release, 2021, 331, 260-269. PMID: 33484778; PMCID: PMC7946725; doi: 10.1016/j.jconrel.2021.01.026 |
| 212 |
“Refined Prediction of Pharmacokinetic Kratom-Drug Interactions: Time-Dependent Inhibition Considerations.”Rakshit S. Tanna, Dan-Dan Tian, Nadja B. Cech, Nicholas H. Oberlies, Journal of Pharmacology and Experimental Therapeutics, 2021, 376, 64-73. PMID: 33093187; PMCID: PMC7745086; doi: 10.1124/jpet.120.000270
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| 211 |
“Capturing the Antimicrobial Profile of Rosmarinus officinalis against Methicillin-Resistant
|
| 210 |
“Cytotoxic Naphthoquinone Analogues, Including Heterodimers, and Their Structure Elucidation Using LR-HSQMBC NMR Experiments.”Laura Flores-Bocanegra, Huzefa A. Raja, Jeffrey W. Bacon, Amanda C. Maldonado, Joanna E. Burdette, Journal of Natural Products, 2021, 84, 771-778 PMID: 33006889; PMCID: PMC8005429; doi: 10.1021/acs.jnatprod.0c00856 |
Amanda C. Maldonado, Joanna E. Burdette, Joseph O. Falkinham, Cedric J. Pearce, and Nicholas H. Oberlies
André Damasio, A. C. dos Santos Renato, L. Labella Abigail, Yuanning Li, L. Knowles Sonja, A. Raja Huzefa, H. Oberlies Nicholas, Xiaofan Zhou, A. Cornely Oliver, Frieder Fuchs, Philipp Koehler, H. Goldman Gustavo, Antonis Rokas, and A. Cuomo Christina
Erika Gasparotto, Hannes Gratzl, Maria Doppler, Michael Sulyok, Alena Kubátová, Harald Berger, Kristof Cank, Huzefa A. Raja, Nicholas H. Oberlies, Christoph Schüller, and Joseph Strauss
Ahmed H. Al Sharie, Rick L. Bunch, and Nicholas H. Oberlies
Soraya Alnabulsi, and Nicholas H. Oberlies
and Nicholas H. Oberlies
Cedric J. Pearce, Mitchell P. Croatt, and Nicholas H. Oberlies
Joseph O. Falkinham, Scott E. Hemby, and Nicholas H. Oberlies
Cedric J. Pearce, James R. Fuchs, and Nicholas H. Oberlies
Huzefa A. Raja, Kimberly N. Heath-Borrero, Joanna E. Burdette, Joseph O. Falkinham III, Cedric J. Pearce, and Nicholas H. Oberlies
Joanna E. Burdette, Cedric J. Pearce, and Nicholas H. Oberlies
Tyler N. Graf, Yin P. Hung, Cedric J. Pearce, Mark W. Grinstaff, Aaron H. Colby, Yolonda L. Colson, and Nicholas H. Oberlies
Allan E. Rettie, Kenneth E. Thummel, and Mary F. Paine
Nicholas H. Oberlies, Nadja B. Cech, and Joëlle Houriet
Cedric J. Pearce, and Nicholas H. Oberlies2020
| 209 |
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| 208 |
“Bioactive Diterpenoid Metabolism and Cytotoxic Activities of Genetically Transformed Euphorbia Lathyris Roots.”Vincent A. Ricigliano, Vincent P. Sica, Sonja L. Knowles, Nicole Phytochemistry, 2020, 179, 112504. PMID: 32980713; PMCID: PMC7863580; doi: 10.1016/j.phytochem.2020.112504 |
| 207 |
“Phenethyisoquinoline Alkaloids from the Leaves of Androcymbium palaestinum.”Tamam El-Elimat, Maram B. Alhawarri, José Rivera-Chávez, Joanna E. Fitoterapia, 2020, 146, 104706. PMID: 32829012; PMCID: PMC7871506; doi: 10.1016/j.fitote.2020.104706 |
| 206 |
“Enhanced Production and Anticancer Properties of Photoactivated Perylenequinones.”Zeinab Y. Al Subeh, Huzefa A. Raja, Susan Monro, Laura Flores-Bocanegra, Tamam El-Elimat, Journal of Natural Products, 2020, 83, 2490-2500. PMID: 32786877; PMCID: PMC7493285; doi: 10.1021/acs.jnatprod.0c00492 Erratum in Correction to Enhanced Production and Anticancer Properties of Photoactivated Perylenequinones [Journal of Natural Products, 2020, 83, 3765-3766]. PMID: 33314937; doi: 10.1021/acs.jnatprod.0c01289 |
| 205 |
“Chemical Composition and Biological Effects of Kratom (Mitragyna Speciosa): In Vitro Studies with Implications for Efficacy and Drug Interactions”Daniel A. Todd, Joshua J. Kellogg, E. Diane Wallace, Manead Khin, Scientific Reports, 2020, 10, 19158. PMID: 33154449; PMCID: PMC7645423; doi: 10.1038/s41598-020-76119-w |
| 204 |
“The Chemistry of Kratom [Mitragyna speciosa]: Updated Characterization Data and Methods to Elucidate Indole and Oxindole Alkaloids”
Journal of Natural Products, 2020, 83(7), 2165-2177. PMID: 32597657; PMCID: PMC7718854; doi: 10.1021/acs.jnatprod.0c00257 |
| 203 |
“Pathogenic Allodiploid Hybrids of Aspergillus Fungi”
Current Biology, 2020, 30(13), 2495-2507.e7. PMID: 32502407, PMCID: PMC7343619, doi: 10.1016/j.cub.2020.04.071 |
| 202 |
“Biosynthetic Gene Clusters and the Evolution of Fungal Chemodiversity”
Natural Product Reports, 2020, 37(7), 868-878. PMID: 31898704, PMCID: PMC7332410, doi: 10.1039/c9np00045c |
| 201 |
“Drug Leads from Endophytic Fungi: Lessons Learned via Scaled Production”
Planta Medica, 2020, 86, 988-996. PMID: 32219776; PMCID: PMC7511429; doi: 10.1055/a-1130-4856 |
| 200 |
“Wheldone: Characterization of a Unique Scaffold from the Coculture of Aspergillus fischeri and Xylaria flabelliformis.”
Organic Letters, 2020, 22, 1878-1882. PMID: 32096649; PMCID: PMC7153779; doi: 10.1021/acs.orglett.0c00219 |
| 199 |
“Evolving Moldy Murderers: Aspergillus Section Fumigati as a Model for Studying the Repeated Evolution of Fungal Pathogenicity.”
PLOS Pathogens, 2020, 16, e1008315. PMID: 32106242; PMCID: PMC7046185; doi: 10.1371/journal.ppat.1008315 |
| 198 |
“Gliotoxin, a Known Virulence Factor in the Major Human Pathogen Aspergillus fumigatus, Is Also Biosynthesized by Its Nonpathogenic Relative Aspergillus fischeri.”
mBio, 2020, 11, e03361-03319. PMID: 32047138; PMCID: PMC7018655; doi: 10.1128/mBio.03361-19 |
| 197 |
“New Tricks for Old Dogs: Two New Macrocyclic Trichothecene Epimers and Absolute Configuration of 16-Hydroxyverrucarin B.”
Phytochemistry, 2020, 172, 112238. PMID: 31931448; PMCID: PMC7050405; |
| 196 |
“Verticillin A Causes Apoptosis and Reduces Tumor Burden in High-Grade Serous Ovarian Cancer by Inducing DNA Damage.”
Molecular Cancer Therapeutics, 2020, 19, 89-100. PMID: 31909733; PMCID: PMC6951445; |
| 195 |
“Syntaxin 6-Mediated Exosome Secretion Regulates Enzalutamide Resistance in Prostate Cancer.”
Molecular Carcinogenesis, 2020, 59, 62-72. PMID: 31674708; PMCID: PMC6916724; doi: 10.1002/mc.23129 |
“Variation among Biosynthetic Gene Clusters, Secondary Metabolite Profiles, and Cards of Virulence across Aspergillus Species.”
Diette, Dianella G. Howarth, and Nicholas H. Oberlies
Burdette, Austin Czarnecki, Mohammad Al-Gharaibeh, Ahmed H. Al Sharie, Ahmed Alhusban, Feras Q. Alali, and Nicholas H. Oberlies
Cedric J. Pearce, Sherri A. McFarland, and Nicholas H. Oberlies
Laura Flores-Bocanegra, Rakshit S. Tanna, Scot McIntosh, Huzefa A. Raja, Tyler N. Graf, Scott E. Hemby, Mary F. Paine, Nicholas H. Oberlies, and Nadja B. Cech
2019
| 194 |
“Droplet Probe: Coupling Chromatography to the In Situ Evaluation of the Chemistry of Nature.”
Natural Product Reports, 2019, 36, 944-959. PMID: 31112181; PMCID: PMC6640111; doi: 10.1039/c9np00019d |
| 193 |
“Development of a Consensus Approach for Botanical Safety Evaluation – A Roundtable Report.”Corrado L. Galli, Nigel J. Walker, Nicholas H. Oberlies, Amy L. Roe, James Edwards, Suzanne Fitzpatrick, James C. Griffiths, A. Wallace Hayes, Catherine Mahony, Daniel S. Marsman, and Lara O’Keeffe Toxicology Letters, 2019, 314, 10-17. |
| 192 |
“Selection and Characterization of Botanical Natural Products for Research Studies: A NaPDI Center Recommended Approach.”
Natural Product Reports, 2019, 36, 1196-1221. PMID: 30681109; PMCID: PMC6658353; doi: 10.1039/c8np00065d |
| 191 |
“An Unusual Burkholderia gladioli double Chain-Initiating Nonribosomal Peptide Synthetase Assembles ‘Fungal’ Icosalide Antibiotics.”
Chemical Science, 2019, 10, 5489-5494. PMID: 31293732; PMCID: PMC6553374; doi: 10.1039/c8sc04897e |
| 190 |
“Metabolites from the Marine-facultative Aspergillus sp. MEXU 27854 and Gymnoascus hyalinosporus MEXU 29901 from Caleta Bay, Mexico.”
Tetrahedron Letters, 2019, 60, 1649-1652. PMID: 32390667; PMCID: PMC7207482; doi: 10.1016/j.tetlet.2019.05.037 |
| 189 |
“Pheophorbide Derivatives Isolated From Açaí Berries (Euterpea oleracea) Activate an Antioxidant Response Element In Vitro.”Suneel K. Kandagatla, Robin Tate Uhl, Tyler N. Graf, Nicholas H. Oberlies, and Gregory M. Raner Natural Product Communications, 2019, 14. PMID: 33214801; PMCID: PMC7673296; doi: 10.1177/1934578X19852443 |
| 188 |
“Apicidin Attenuates MRSA Virulence through Quorum-Sensing Inhibition and Enhanced Host Defense.”
Cell Reports, 2019, 27, 187-198.e186. PMID: 30943400; PMCID: PMC7224364; doi: 10.1016/j.celrep.2019.03.018
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| 187 |
“Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines.”
Biomolecules, 2019, 9, 126. PMID: 30934922; PMCID: PMC6523683; doi: 10.3390/biom9040126 |
| 186 |
“Prenylated Diresorcinols Inhibit Bacterial Quorum Sensing.”
Journal of Natural Products, 2019, 82, 550-558. PMID: 30730742; doi: 10.1021/acs.jnatprod.8b00925
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| 185 |
“SUV39H1 Represses the Expression of Cytotoxic T-Lymphocyte Effector Genes to Promote Colon Tumor Immune Evasion.”Chunwan Lu, Dafeng Yang, John D. Klement, Il Kyu Oh, Natasha M. Savage, Jennifer L. Waller, Aaron H. Colby, Mark W. Grinstaff, Nicholas H. Oberlies, Cedric J. Pearce, Zhiliang Xie, Samuel K. Kulp, Christopher C. Coss, Mitch A. Phelps, Thomas Albers, Iryna O. Lebedyeva, and Kebin Liu Cancer Immunology Research, 2019, 7, 414. PMID: 30610059; PMCID: PMC6397681; doi: 10.1158/2326-6066.CIR-18-0126 |
| 184 |
“Engineering Fluorine into Verticillins (Epipolythiodioxopiperazine Alkaloids) via Precursor-Directed Biosynthesis.”
Journal of Natural Products, 2019, 82, 3104-3110. PMID: 31633350; PMCID: PMC6996222; doi: 10.1021/acs.jnatprod.9b00711 |
| 183 |
“Orthogonal Method for Double-Bond Placement via Ozone-Induced Dissociation Mass Spectrometry (OzID-MS).”
Journal of Natural Products, 2019, 82, 3421-3431. PMID: 31823607; PMCID: PMC7004233; doi: 10.1021/acs.jnatprod.9b00787 |
| 182 |
“Draft Genome Sequence of the Griseofulvin-Producing Fungus Xylaria flabelliformis Strain G536.”
Microbiology Resource Announcements, 2019, 8, e00890-00819. PMID: 31537670; PMCID: PMC6753274; doi: 10.1128/MRA.00890-19 |
| 181 |
“Mapping the Fungal Battlefield: Using in situ Chemistry and Deletion Mutants to Monitor Interspecific Chemical Interactions between Fungi.”
Frontiers in Microbiology, 2019, 10, 285. PMID: 30837981; PMCID: PMC6389630; doi: 10.3389/fmicb.2019.00285 |
| 180 |
“Characterizing the Pathogenic, Genomic, and Chemical Traits of Aspergillus fischeri, a Close Relative of the Major Human Fungal Pathogen Aspergillus fumigatus.”
mSphere, 2018, 4, e00018-00019. PMID: 30787113; PMCID: PMC6382966, doi: 10.1128/mSphere.00018-19 |
| 179 |
“Meroterpenoids from Neosetophoma Sp.: A Dioxa[4.3.3]Propellane Ring System, Potent Cytotoxicity, and Prolific Expression.”
Organic Letters, 2019, 21, 529-534. PMID: 30620608; PMCID: PMC6343109; doi: 10.1021/acs.orglett.8b03769 |
| 178 |
“Delitpyrones: α-Pyrone Derivatives from a Freshwater Delitschia Sp.”
Planta Medica, 2019, 85, 62-71. PMID: 30016827; doi: 10.1055/a-0654-5850 |
| 177 |
“Mycopyranone: A 8,8ˈ-Binaphthopyranone with Potent Anti-Mrsa Activity from the Fungus Phialemoniopsis Sp.”
Tetrahedron Letters, 2019, 60, 594-597. PMID: 31598014; PMCID: PMC6785197; doi: 10.1016/j.tetlet.2019.01.029 |
| 176 |
“The Value of Universally Available Raw NMR Data for Transparency, Reproducibility, and Integrity in Natural Product Research.”
Natural Product Reports, 2019, 36, 35-107. PMID: 30003207; PMCID: PMC6350634; doi: 10.1039/c7np00064b Erratum in |
| 175 |
“Silymarin Prevents Memory Impairments, Anxiety, and Depressive-Like Symptoms in a Rat Model of Post-Traumatic Stress Disorder.”
Planta Medica, 2019, 85, 32-40. PMID: 30153692; doi: 10.1055/a-0710-5673 |
Joshua J. Kellogg, Mary F. Paine, Jeannine S. McCune, Nicholas H. Oberlies, and Nadja B. Cech
Matthew Jenner, Xinyun Jian, Yousef Dashti, Joleen Masschelein, Christian Hobson, Douglas M. Roberts, Cerith Jones, Simon Harris, Julian Parkhill, Huzefa A. Raja, Nicholas H. Oberlies, Cedric J. Pearce, Eshwar Mahenthiralingam, and Gregory L. Challis
Noemi D. Paguigan, José Rivera-Chávez, Justin J. Stempin, Mario Augustinović, Aleksandra I. Noras, Huzefa A. Raja, Daniel A. Todd, Kathleen D. Triplett, Cynthia Day, Mario Figueroa, Pamela R. Hall, Nadja B. Cech, and Nicholas H. Oberlies
James B. McAlpine, Shao-Nong Chen, Andrei Kutateladze, John B. MacMillan, Giovanni Appendino, Andersson Barison, Mehdi A. Beniddir, Maique W. Biavatti, Stefan Bluml, Asmaa Boufridi, Mark S. Butler, Robert J. Capon, Young H. Choi, David Coppage, Phillip Crews, Michael T. Crimmins, Marie Csete, Pradeep Dewapriya, Joseph M. Egan, Mary J. Garson, Grégory Genta-Jouve, William H. Gerwick, Harald Gross, Mary Kay Harper, Precilia Hermanto, James M. Hook, Luke Hunter, Damien Jeannerat, Nai-Yun Ji, Tyler A. Johnson, David G. I. Kingston, Hiroyuki Koshino, Hsiau-Wei Lee, Guy Lewin, Jie Li, Roger G. Linington, Miaomiao Liu, Kerry L. McPhail, Tadeusz F. Molinski, Bradley S. Moore, Joo-Won Nam, Ram P. Neupane, Matthias Niemitz, Jean-Marc Nuzillard, Nicholas H. Oberlies, Fernanda M. M. Ocampos, Guohui Pan, Ronald J. Quinn, D. Sai Reddy, Jean-Hugues Renault, José Rivera-Chávez, Wolfgang Robien, Carla M. Saunders, Thomas J. Schmidt, Christoph Seger, Ben Shen, Christoph Steinbeck, Hermann Stuppner, Sonja Sturm, Orazio Taglialatela-Scafati, Dean J. Tantillo, Robert Verpoorte, Bin-Gui Wang, Craig M. Williams, Philip G. Williams, Julien Wist, Jian-Min Yue, Chen Zhang, Zhengren Xu, Charlotte Simmler, David C. Lankin, Jonathan Bisson, and Guido F. Pauli
2018
| 174 |
“Non-Destructive Chemical Analysis of a Garcinia mangostana L. (Mangosteen) Herbarium Voucher Specimen.”Diana Kao, Joshua M.Henkin, Djaja Djendoel Soejarto, A. Douglas Kinghorn, and Nicholas H.Oberlies Phytochemistry Letters, 2018, 28, 124-129. PMID: 30613309; PMCID: PMC6317376; doi: 10.1016/j.phytol.2018.10.001 |
| 173 |
“Media Studies to Enhance the Production of Verticillins Facilitated by in Situ Chemical Analysis.”Chiraz Soumia M. Amrine, Huzefa A. Raja, Blaise A. Darveaux, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Industrial Microbiology & Biotechnology, 2018, 45, 1053-1065. PMID: 30259213; PMCID: PMC6251749; doi: 10.1007/s10295-018-2083-8 |
| 172 |
“Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides to Form Nitriles.”Mohammed H. Al-Huniti, José Rivera-Chávez, Katsuya L. Colón, Jarrod L. Stanley, Joanna E. Burdette, Cedric J. Pearce, Nicholas H. Oberlies, and Mitchell P. Croatt Organic Letters, 2018, 20, 6046-6050. PMID: 30221526; PMCID: PMC6179452; doi: 10.1021/acs.orglett.8b02422 |
| 171 |
“Calothrixamides a and B from the Cultured Cyanobacterium Calothrix Sp. Uic 10520.”Camila M. Crnkovic, Aleksej Krunic, Daniel S. May, Tyler A. Wilson, Diana Kao, Joanna E. Burdette, James R. Fuchs, Nicholas H. Oberlies, and Jimmy Orjala Journal of Natural Products, 2018, 81, 2083-2090. PMID: 30192537; PMCID: PMC6359934; doi: 10.1021/acs.jnatprod.8b00432 |
| 170 |
“Fungal Planet Description Sheets: 716-784.”P.W. Crous, M.J. Wingfield, T.I. Burgess, G.E.St.J. Hardy, J. Gené, J. Guarro, I.G. Baseia, D. García, L.F.P. Gusmão, C.M. Souza-Motta, R. Thangavel, S. Adamčík, A. Barili, C.W. Barnes, J.D.P. Bezerra, J.J. Bordallo, J.F. Cano-Lira, R.J.V. de Oliveira, E. Ercole, V. Hubka, I. Iturrieta-González, A. Kubátová, M.P. Martín, P.-A. Moreau, A. Morte, M.E. Ordoñez, A. Rodríguez, A.M. Stchigel, A. Vizzini, J. Abdollahzadeh, V.P. Abreu, K. Adamčíková, G.M.R. Albuquerque, A.V. Alexandrova, E. Álvarez Duarte, C. Armstrong-Cho, S. Banniza, R.N. Barbosa, J.-M. Bellanger, J.L. Bezerra, T.S. Cabral, M. Caboň, E. Caicedo, T. Cantillo, A.J. Carnegie, L.T. Carmo, R.F. Castañeda-Ruiz, C.R. Clement, A. Čmoková, L.B. Conceição, R.H.S.F. Cruz, U. Damm, B.D.B. da Silva, G.A. da Silva, R.M.F. da Silva, A.L.C.M. de A. Santiago, L.F. de Oliveira, C.A.F. de Souza, F. Déniel, B. Dima, G. Dong, J. Edwards, C.R. Félix, J. Fournier, T.B. Gibertoni, K. Hosaka, T. Iturriaga, M. Jadan, J.-L. Jany, Ž. Jurjević, M. Kolařík, I. Kušan, M.F. Landell, T.R. Leite Cordeiro, D.X. Lima, M. Loizides, S. Luo, A.R. Machado, H. Madrid, O.M.C. Magalhães, P. Marinho, N. Matočec, A. Mešić, A.N. Miller, O.V. Morozova, R.P. Neves, K. Nonaka, A. Nováková, N.H. Oberlies, J.R.C. Oliveira-Filho, T.G.L. Oliveira, V. Papp, O.L. Pereira, G. Perrone, S.W. Peterson, T.H.G. Pham, H.A. Raja, D.B. Raudabaugh, J. Řehulka, E. Rodríguez-Andrade, M. Saba, A. Schauflerová, R.G. Shivas, G. Simonini, J.P.Z. Siqueira, J.O. Sousa, V. Stajsic, T. Svetasheva, Y.P. Tan, Z. Tkalčec, S. Ullah, P. Valente, N. Valenzuela-Lopez, M. Abrinbana, D.A. Viana Marques, P.T.W. Wong, V. Xavier de Lima, and J.Z. Groenewald Persoonia – Molecular Phylogeny and Evolution of Fungi, 2018, 40, 239-392. PMID: 30505003; PMCID: PMC6146637; doi: 10.3767/persoonia.2018.40.10 |
| 169 |
“Reinforcement of Polymeric Nanoassemblies for Ultra-High Drug Loadings, Modulation of Stiffness and Release Kinetics, and Sustained Therapeutic Efficacy.”Iriny Ekladious, Rong Liu, Nitinun Varongchayakul, Luis A. Mejia Cruz, Daniel A. Todd, Heng Zhang, Nicholas H. Oberlies, Robert F. Padera, Yolonda L. Colson, and Mark W. Grinstaff Nanoscale, 2018, 10, 8360-8366. PMID: 29717728; doi: 10.1039/c8nr01978a |
| 168 |
“Identification of Intestinal Udp-Glucuronosyltransferase Inhibitors in Green Tea (Camellia sinensis) Using a Biochemometric Approach: Application to Raloxifene as a Test Drug Via in Vitro to in Vivo Extrapolation.”Dan-Dan Tian, Joshua J. Kellogg, Neşe Okut, Nicholas H. Oberlies, Nadja B. Cech, Danny D. Shen, Jeannine S. McCune, and Mary F. Paine Drug Metabolism and Disposition, 2018, 46, 552. PMID: 29467215; PMCID: PMC5890833; doi: 10.1124/dmd.117.079491 |
| 167 |
“Detection of Adulteration in Hydrastis canadensis (Goldenseal) Dietary Supplements via Untargeted Mass Spectrometry-Based Metabolomics.”Emily D. Wallace, Nicholas H. Oberlies, Nadja B. Cech, and Joshua J. Kellogg Food and Chemical Toxicology, 2018, 120, 439-447. PMID: 30031041; PMCID: PMC6434943; doi: 10.1016/j.fct.2018.07.033 |
| 166 |
“Cytotoxic Homoisoflavonoids from the Bulbs of Bellevalia flexuosa.”Tamam El-Elimat, José Rivera-Chávez, Joanna E. Burdette, Austin Czarnecki, Maram B. Alhawarri, Mohammad Al-Gharaibeh, Feras Alali, and Nicholas H. Oberlies Fitoterapia, 2018, 127, 201-206. PMID: 29471027; PMCID: PMC5984119; doi: 10.1016/j.fitote.2018.02.022 |
| 165 |
“Contrasting Roles of H3K4me3 and H3K9me3 in Regulation of Apoptosis and Gemcitabine Resistance in Human Pancreatic Cancer Cells.”Chunwan Lu, Dafeng Yang, Maria E. Sabbatini, Aaron H. Colby, Mark W. Grinstaff, Nicholas H. Oberlies, Cedric Pearce, and Kebin Liu BMC Cancer, 2018, 18, 149. PMID: 29409480; PMCID: PMC5801751; doi: 10.1186/s12885-018-4061-y |
| 164 |
“Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines.”Kirti S. Prabhu, Kodappully Sivaraman Siveen, Shilpa Kuttikrishnan, Ahmad N. Iskandarani, Abdul Q. Khan, Maysaloun Merhi, Halima E. Omri, Said Dermime, Tamam El-Elimat, Nicholas H. Oberlies, Feras Q. Alali, and Shahab Uddin Frontiers in Pharmacology, 2018, 9, 720. PMID: 30061828; PMCID: PMC6054921; doi: 10.3389/fphar.2018.00720 |
2017
| 163 |
“Prealamethicin F50 and Related Peptaibols from Trichoderma arundinaceum: Validation of their Authenticity via in situ Chemical Analysis.”José Rivera-Chávez, Huzefa A. Raja, Tyler N. Graf, Jacklyn M. Gallagher, Prashant Metri, Ding Xue, Cedric J. Pearce, and Nicholas H. Oberlies RSC Advances, 2017, 7, 45733-45751. PMID: 29379602; PMCID: PMC5786278; doi: 10.1039/c7ra09602j |
| 162 |
“Conventional and Accelerated-Solvent Extractions of Green Tea (Camellia sinensis) for Metabolomics-Based Chemometrics.”Joshua J. Kellogg, Emily D. Wallace, Tyler N. Graf, Nicholas H. Oberlies, and Nadja B. Cech Journal of Pharmaceutical and Biomedical Analysis, 2017, 145, 604-610. PMID: 28787673; PMCID: PMC5804813; doi: 10.1016/j.jpba.2017.07.027 |
| 161 |
“Chemoselective Fluorination and Chemoinformatic Analysis of Griseofulvin: Natural vs Fluorinated Fungal Metabolites.”Noemi D. Paguigan, Mohammed H. Al-Huniti, Huzefa A. Raja, Austin Czarnecki, Joanna E. Burdette, Mariana González-Medina, José L. Medina-Franco, Stephen J. Polyak, Cedric J. Pearce, Mitchell P. Croatt, and Nicholas H. Oberlies Bioorganic & Medicinal Chemistry, 2017, 25, 5238-5246. PMID: 28802670; PMCID: PMC5632135; doi: 10.1016/j.bmc.2017.07.041 |
| 160 |
“Biosynthesis of Fluorinated Peptaibols Using a Site-Directed Building Block Incorporation Approach.”José Rivera-Chávez, Huzefa A. Raja, Tyler N. Graf, Joanna E. Burdette, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Natural Products, 2017, 80, 1883-1892. PMID: 28594169; PMCID: PMC5485375; doi: 10.1021/acs.jnatprod.7b00189 |
| 159 |
“Synthesis of Poly(1,2-Glycerol Carbonate)-Paclitaxel Conjugates and Their Utility as a Single High-Dose Replacement for Multi-Dose Treatment Regimens in Peritoneal Cancer.”Iriny Ekladious, Rong Liu, Heng Zhang, Daniel H. Foil, Daniel A. Todd, Tyler N. Graf, Robert F. Padera, Nicholas H. Oberlies, Yolonda L. Colson, and Mark W. Grinstaff Chemical Science, 2017, 8, 8443-8450. PMID: 29619192; PMCID: PMC5863611; doi: 10.1039/C7SC03501B |
| 158 |
“In Situ Mass Spectrometry Monitoring of Fungal Cultures Led to the Identification of Four Peptaibols with a Rare Threonine Residue.”Vincent P. Sica, Evan R. Rees, Huzefa A. Raja, José Rivera-Chávez, Joanna E. Burdette, Cedric J. Pearce, and Nicholas H. Oberlies Phytochemistry, 2017, 143, 45-53. PMID: 28772192; PMCID: PMC5603414; doi: 10.1016/j.phytochem.2017.07.004 |
| 157 |
“Comparison of Metabolomics Approaches for Evaluating the Variability of Complex Botanical Preparations: Green Tea (Camellia sinensis) as a Case Study.”Joshua J. Kellogg, Tyler N. Graf, Mary F. Paine, Jeannine S. McCune, Olav M. Kvalheim, Nicholas H. Oberlies, and Nadja B. Cech Journal of Natural Products, 2017, 80, 1457-1466. PMID: 28453261; PMCID: PMC5469520; doi: 10.1021/acs.jnatprod.6b01156 |
| 156 |
“Characterization and Isolation of Peptide Metabolites of an Antifungal Bacterial Isolate Identified as Bacillus Amyloliquefaciens Subspecies plantarum Strain FZB42.”Abiodun Adibi, Evan R. Rees, Saudia McCarley, Vincent P. Sica, and Nicholas H. Oberlies Journal of Microbiology, Biotechnology and Food Sciences, 2017, 6, 1309-1313. |
| 155 |
“Secondary Metabolites from the Leaves of the Medicinal Plant Goldenseal (Hydrastis canadensis).”Martha Leyte-Lugo, Emily R. Britton, Daniel H. Foil, Adam R. Brown, Daniel A. Todd, José Rivera-Chávez, Nicholas H. Oberlies, and Nadja B. Cech Phytochemistry Letters, 2017, 20, 54-60. PMID: 28736584; PMCID: PMC5516942; doi: 10.1016/j.phytol.2017.03.012 |
| 154 |
“qNMR for Profiling the Production of Fungal Secondary Metabolites.”Wilson C. Brooks, Noemi D. Paguigan, Huzefa A. Raja, Franklin J. Moy, Nadja B. Cech, Cedric J. Pearce, and Nicholas H. Oberlies Magnetic Resonance in Chemistry, 2017, 55, 670-676. PMID: 28024162; PMCID: PMC5459663; doi: 10.1002/mrc.4571 |
| 153 |
“Additions to Lindgomyces (Lindgomycetaceae, Pleosporales, Dothideomycetes), Including Two New Species Occurring on Submerged Wood from North Carolina, USA, with Notes on Secondary Metabolite Profiles.”Huzefa A. Raja, Noemi D. Paguigan, Jacques Fournier, and Nicholas H. Oberlies Mycological Progress, 2017, 16, 535-552. |
| 152 |
“Safety Assessment of Mushrooms in Dietary Supplements by Combining Analytical Data with in Silico Toxicology Evaluation.”Karen M. VanderMolen, Jason G. Little, Vincent P. Sica, Tamam El-Elimat, Huzefa A. Raja, Nicholas H. Oberlies, Timothy R. Baker, and Catherine Mahony Food and Chemical Toxicology, 2017, 103, 133-147. |
| 151 |
“Plasma Pharmacokinetics and Bioavailability of Verticillin A Following Different Routes of Administration in Mice Using Liquid Chromatography Tandem Mass Spectrometry.”Jiang Wang, Xiaohua Zhu, Shamala Kolli, Hongyan Wang, Cedric J. Pearce, Nicholas H. Oberlies, and Mitch A. Phelps Journal of Pharmaceutical and Biomedical Analysis, 2017, 139, 187-192. PMID: 28284083; PMCID: PMC5399420; doi: 10.1016/j.jpba.2017.02.051 |
| 150 |
“Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community.”Huzefa A. Raja, Andrew N. Miller, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Natural Products, 2017, 80, 756-770. PMID: 28199101; PMCID: PMC5368684; doi: 10.1021/acs.jnatprod.6b01085 |
| 149 |
“DNA Barcoding for Identification of Consumer-Relevant Mushrooms: A Partial Solution for Product Certification?”Huzefa A. Raja, Timothy R. Baker, Jason G. Little, and Nicholas H. Oberlies Food Chemistry, 2017, 214, 383-392. |
| 148 |
“Enhanced Dereplication of Fungal Cultures Via Use of Mass Defect Filtering.”Noemi D. Paguigan, Tamam El-Elimat, Diana Kao, Huzefa A. Raja, Cedric J. Pearce, and Nicholas H. Oberlies The Journal of Antibiotics, 2017, 70, 553-561. PMID: 28074050 PMCID; PMC5407915; doi: 10.1038/ja.2016.145 |
| 147 |
“The MLL1-H3K4me3 Axis-Mediated PD-L1 Expression and Pancreatic Cancer Immune Evasion.”Chunwan Lu, Amy V. Paschall, Huidong Shi, Natasha Savage, Jennifer L. Waller, Maria E. Sabbatini, Nicholas H. Oberlies, Cedric Pearce, and Kebin Liu Journal of the National Cancer Institute, 2017, 109, djw283. PMID: 28131992 PMCID; PMC5291187; doi: 10.1093/jnci/djw283 |
| 146 |
“Scaffold Diversity of Fungal Metabolites.”Mariana González-Medina, John R. Owen, Tamam El-Elimat, Cedric J. Pearce, Nicholas H. Oberlies, Mario Figueroa, and José L. Medina-Franco Frontiers in Pharmacology, 2017, 8, 180. PMID: 28420994; PMCID: PMC5376591; doi: 10.3389/fphar.2017.00180 |
| 145 |
“Nanoparticle Drug-Delivery Systems for Peritoneal Cancers: A Case Study of the Design, Characterization and Development of the Expansile Nanoparticle.”Aaron H. Colby, Nicholas H. Oberlies, Cedric J. Pearce, Victoria L. M. Herrera, Yolonda L. Colson, and Mark W. Grinstaff Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2017, 9, e1451-n/a. PMID: 28185434; PMCID: PMC5389910; doi: 10.1002/wnan.1451 |
| 144 |
“a-Pyrone Derivatives, Tetra/Hexahydroxanthones, and Cyclodepsipeptides from Two Freshwater Fungi.”Tamam El-Elimat, Huzefa A Raja, Cynthia S. Day, Hana McFeeters, Robert L. McFeeters, and Nicholas H. Oberlies Bioorganic & Medicinal Chemistry, 2017, 25, 795-804. |
2016
| 143 |
“Discovery of Anticancer Agents of Diverse Natural Origin.”Douglas Kinghorn, Esperanza J. Carcache De Blanco, David M. Lucas, H. Liva Rakotondraibe, Jimmy Orjala, D. Doel Soejarto, Nicholas H. Oberlies, Cedric J. Pearce, Mansukh C. Wani, Brent R. Stockwell, Joanna E. Burdette, Steven M. Swanson, James R. Fuchs, Mitchell A. Phelps, Lihui Xu, Xiaoli Zhang, and Young Yongchun Shen Anticancer Research, 2016, 36, 5623-5637. PMID: 27793884; PMCID: PMC5098703; doi: 10.21873/anticanres.11146 |
| 142 |
“Chemoinformatic Expedition of the Chemical Space of Fungal Products.”Mariana González-Medina, Fernando D. Prieto-Martínez, J. Jesús Naveja, Oscar Méndez-Lucio, Tamam El-Elimat, Cedric J. Pearce, Nicholas H. Oberlies, Mario Figueroa, and José L. Medina-Franco Future Medicinal Chemistry, 2016, 8, 1399-1412. PMID: 27485744; PMCID: PMC5558535; doi: 10.4155/fmc-2016-0079 |
| 141 |
“Antimicrobial Fungal Endophytes from the Botanical Medicine Goldenseal (Hydrastis canadensis).”Joseph M. Egan, Amninder Kaur, Huzefa A. Raja, Joshua J. Kellogg, Nicholas H.Oberlies, and Nadja B.Cech Phytochemistry Letters, 2016, 17, 219-225. PMID: 28603575; PMCID: PMC5461979; doi: 10.1016/j.phytol.2016.07.031 |
| 140 |
“Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells.”Amninder Kaur, Martina Oberhofer, Monika Juzumaite, Huzefa A. Raja, Travis V. Gulledge, Diana Kao, Stanley H. Faeth, Scott M. Laster, Nicholas H. Oberlies, and Nadja B. Cech Natural Product Communications, 2016, 11, 1143-1146. PMID: 28479944; PMCID: PMC5414731 |
| 139 |
“In Situ Analysis of Asimina triloba (Paw Paw) Plant Tissues for Acetogenins via the Droplet-Liquid Microjunction-Surface Sampling Probe Coupled to UHPLC-PDA-HRMS/MS.”Vincent P .Sica, Tamam El-Elimat, and Nicholas H. Oberlies Analytical Methods, 2016, 8, 6143-6149. |
| 138 |
“Verticillin A Inhibits Leiomyosarcoma and Malignant Peripheral Nerve Sheath Tumor Growth Via Induction of Apoptosis.”Abbie Zewdu, Gonzalo Lopez, Danielle Braggio, Connor Kenney, Constantino D, Hemant Bid, Kara Batte, O. Hans Iwenofu, Nicholas H. Oberlies, Cedric J. Pearce, Anne Strohecker, Dina Lev, and Raphael E. Pollock Clinical and Experimental Pharmacology, 2016, 06. PMID: 28184331; PMCID: PMC5295762; doi: 10.4172/2161-1459.1000221 |
| 137 |
“Optimizing Production and Evaluating Biosynthesis in Situ of a Herbicidal Compound, Mevalocidin, from Coniolariella Sp.”Vincent P. Sica, Mario Figueroa, Huzefa A. Raja, Tamam El-Elimat, Blaise A. Darveaux, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Industrial Microbiology & Biotechnology, 2016, 43, 1149-1157. |
| 136 |
“Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages.”Limei Wang, Susanne Rotter, Angela Ladurner, H. Elke Heiss, H. Nicholas Oberlies, M. Verena Dirsch, and G. Atanas Atanasov Molecules, 2016, 21, . PMID: 26729088; PMCID: PMC4748397; doi: 10.3390/molecules21010055 |
| 135 |
“Spatial and Temporal Profiling of Griseofulvin Production in Xylaria cubensis Using Mass Spectrometry Mapping.”Vincent Sica, Evan Rees, Edem Tchegnon, Robert Bardsley, Huzefa Raja, and Nicholas Oberlies Frontiers in Microbiology, 2016, 7. PMID: 27199902; PMCID: PMC4844619; doi: 10.3389/fmicb.2016.00544 |
| 134 |
“Acetophenone Derivatives from a Freshwater Fungal Isolate of Recently Described Lindgomyces Madisonensis (G416).”Noemi D. Paguigan, Huzefa A. Raja, Cynthia S. Day, and Nicholas H. Oberlies Phytochemistry, 2016, 126, 59-65. |
| 133 |
“Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds.”Joshua J. Kellogg, Daniel A. Todd, Joseph M. Egan, Huzefa A. Raja, Nicholas H. Oberlies, Olav M. Kvalheim, and Nadja B. Cech Journal of Natural Products, 2016, 79, 376-386. PMID: 26841051; PMCID: PMC5135737; doi: 10.1021/acs.jnatprod.5b01014 |
| 132 |
“Talarolutins A–D: Meroterpenoids from an Endophytic Fungal Isolate of Talaromyces minioluteus.”Amninder Kaur, Huzefa A. Raja, Dale C. Swenson, Rajesh Agarwal, Gagan Deep, Joseph O. Falkinham III, and Nicholas H. Oberlies Phytochemistry, 2016, 126, 4-10. PMID: 27048854; PMCID: PMC4861051; doi: 10.1016/j.phytochem.2016.03.013 |
| 131 |
“A Validated UHPLC-Tandem Mass Spectrometry Method for Quantitative Analysis of Flavonolignans in Milk Thistle (Silybum marianum) Extracts.”Tyler N. Graf, Nadja B. Cech, Stephen J. Polyak, and Nicholas H. Oberlies Journal of Pharmaceutical and Biomedical Analysis, 2016, 126, 26-33. PMID: 27136284; PMCID: PMC4893890; doi: 10.1016/j.jpba.2016.04.028 |
| 130 |
“Graviola Inhibits Hypoxia-Induced NADPH Oxidase Activity in Prostate Cancer Cells Reducing Their Proliferation and Clonogenicity.”Gagan Deep, Rahul Kumar, Anil K. Jain, Deepanshi Dhar, Gati K. Panigrahi, Anowar Hussain, Chapla Agarwal, Tamam El-Elimat, Vincent P. Sica, Nicholas H. Oberlies, and Rajesh Agarwal Scientific Reports, 2016, 6, 23135. PMID: 26979487; PMCID: PMC4793251; doi: 10.1038/srep23135 |
| 129 |
“Pannorin B, a New Naphthopyrone from an Endophytic Fungal Isolate of Penicillium Sp.”Amninder Kaur, Huzefa A. Raja, Gagan Deep, Rajesh Agarwal, and Nicholas H. Oberlies Magnetic Resonance in Chemistry, 2016, 54, 164-167. PMID: 26365944; doi: 10.1002/mrc.4324 |
2015
| 128 |
“Fungal Planet Description Sheets: 371-399.”Crous, P. W., Wingfield, M. J., Le Roux, J. J., Richardson, D. M., Strasberg, D., Shivas, R. G., Alvarado, P., Edwards, J., Moreno, G., Sharma, R., Sonawane, M. S., Tan, Y. P., Altes, A., Barasubiye, T., Barnes, C. W., Blanchette, R. A., Boertmann, D., Bogo, A., Carlavilla, J. R., Cheewangkoon, R., Daniel, R., de Beer, Z. W., de Jesus Yanez-Morales, M., Duong, T. A., Fernandez-Vicente, J., Geering, A. D., Guest, D. I., Held, B. W., Heykoop, M., Hubka, V., Ismail, A. M., Kajale, S. C., Khemmuk, W., Kolarik, M., Kurli, R., Lebeuf, R., Levesque, C. A., Lombard, L., Magista, D., Manjon, J. L., Marincowitz, S., Mohedano, J. M., Novakova, A., Oberlies, N. H., Otto, E. C., Paguigan, N. D., Pascoe, I. G., Perez-Butron, J. L., Perrone, G., Rahi, P., Raja, H. A., Rintoul, T., Sanhueza, R. M., Scarlett, K., Shouche, Y. S., Shuttleworth, L. A., Taylor, P. W., Thorn, R. G., Vawdrey, L. L., Solano-Vidal, R., Voitk, A., Wong, P. T., Wood, A. R., Zamora, J. C., and Groenewald, J. Z. Persoonia, 2015, 35, 264-327. PMID: 26823636; PMCID: PMC4713108; doi: 10.3767/003158515X690269
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| 127 |
“H3K9 Trimethylation Silences FASs Expression to Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.”Amy V. Paschall, Dafeng Yang, Chunwan Lu, Jeong-Hyeon Choi, Xia Li, Feiyan Liu, Mario Figueroa, Nicholas H. Oberlies, Cedric Pearce, Wendy B. Bollag, Asha Nayak-Kapoor, and Kebin Liu The Journal of Immunology, 2015, 195, 1868-1882. PMID: 26136424; PMCID: PMC4530033; doi: 10.4049/jimmunol.1402243 |
| 126 |
“Minutisphaerales (Dothideomycetes, Ascomycota): A New Order of Freshwater Ascomycetes Including a New Family, Minutisphaeraceae, and Two New Species from North Carolina, USA.”Huzefa A. Raja, Tamam El-Elimat, Nicholas H. Oberlies, Carol A. Shearer, Andrew N. Miller, Kazuaki Tanaka, Akira Hashimoto, and Jacques Fournier Mycologia, 2015, 107, 845-862. PMID: 26315030; doi: 10.3852/15-013 |
| 125 |
“Silymarin Suppresses Cellular Inflammation by Inducing Reparative Stress Signaling.”Erica S. Lovelace, Jessica Wagoner, James MacDonald, Theo Bammler, Jacob Bruckner, Jessica Brownell, Richard P. Beyer, Erika M. Zink, Young-Mo Kim, Jennifer E. Kyle, Bobbie-Jo M. Webb-Robertson, Katrina M. Waters, Thomas O. Metz, Federico Farin, Nicholas H. Oberlies, and Stephen J. Polyak Journal of Natural Products, 2015, 78, 1990-2000. PMID: 26186142; PMCID: PMC4703094; doi: 10.1021/acs.jnatprod.5b00288 |
| 124 |
“Isolation, Semisynthesis, Covalent Docking and Transforming Growth Factor Beta-Activated Kinase 1 (TAK1)-Inhibitory Activities of (5Z)-7-Oxozeaenol Analogues.”Lara Fakhouri, Tamam El-Elimat, Dow P. Hurst, Patricia H. Reggio, Cedric J. Pearce, Nicholas H. Oberlies, and Mitchell P. Croatt Bioorganic & Medicinal Chemistry, 2015, 23, 6993-6999. PMID: 26481152; PMCID: PMC4661079; doi: 10.1016/j.bmc.2015.09.037 |
| 123 |
“Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product–Drug Interaction.”Brandon T. Gufford, Gang Chen, Ana G. Vergara, Philip Lazarus, Nicholas H. Oberlies, and Mary F. Paine Drug Metabolism and Disposition, 2015, 43, 1353-1359. PMID: 26070840; PMCID: PMC4538855; doi: 10.1124/dmd.115.065086 |
| 122 |
“Chemoenzymatic Synthesis, Characterization, and Scale-up of Milk Thistle Flavonolignan Glucuronides.”Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies, and Mary F. Paine Drug Metabolism and Disposition, 2015, 43, 1734-1743. PMID: 26316643; PMCID: PMC4613946; doi: 10.1124/dmd.115.066076 |
| 121 |
“Spiroscytalin, a New Tetramic Acid and Other Metabolites of Mixed Biogenesis fromScytalidium cuboideum.”Arlene A. Sy-Cordero, Mario Figueroa, Huzefa A. Raja, Maria Elena Meza Aviña, Mitchell P. Croatt, Audrey F. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies Tetrahedron, 2015, 71, 8899-8904. PMID: 26525642; PMCID: PMC4624200; doi: 10.1016/j.tet.2015.09.073 |
| 120 |
“Cytotoxic Homoisoflavones from the Bulbs of Bellevalia eigii.”Feras Q. Alali, Tamam El-Elimat, Hanan Albataineh, Qosay Al-Balas, Mohammad Al-Gharaibeh, Joseph O. Falkinham, Wei-Lun Chen, Steven M. Swanson, and Nicholas H. Oberlies Journal of Natural Products, 2015, 78, 1708-1715. PMID: 26147490; PMCID: PMC4615712; doi: 10.1021/acs.jnatprod.5b00357 |
| 119 |
“New Diketopiperazine Dimer from a Filamentous Fungal Isolate of Aspergillus sydowii.”Amninder Kaur, Huzefa A. Raja, Blaise A. Darveaux, Wei-Lun Chen, Steven M. Swanson, Cedric J. Pearce, and Nicholas H. Oberlies Magnetic Resonance in Chemistry, 2015, 53, 616-619. PMID: 26040447; PMCID: PMC4692248; doi: 10.1002/mrc.4254 |
| 118 |
“Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Cultures in Situ.”Vincent P .Sica, Huzefa A. Raja, Tamam El-Elimat, Vilmos Kertesz, Gary J.Van Berkel, Cedric J.Pearce, and Nicholas H.Oberlies Journal of Natural Products, 2015, 78, 1926-1936. PMID: 26192135; PMCID: PMC4570219; doi: 10.1021/acs.jnatprod.5b00268 |
| 117 |
“Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria.”Daniel A. Todd, Travis V. Gulledge, Emily R. Britton, Martina Oberhofer, Martha Leyte-Lugo, Ashley N. Moody, Tatsiana Shymanovich, Laura F. Grubbs, Monika Juzumaite, Tyler N. Graf, Nicholas H. Oberlies, Stanley H. Faeth, Scott M. Laster, and Nadja B. Cech Plos One, 2015, 10, e0124276. PMID: 25933416; PMCID: PMC4416932; doi: 10.1371/journal.pone.0124276 |
| 116 |
“Phylogenetic and Chemical Diversity of Fungal Endophytes Isolated from Silybum marianum(L) Gaertn. (Milk Thistle).”Huzefa A. Raja, Amninder Kaur, Tamam El-Elimat, Mario Figueroa, Rahul Kumar, Gagan Deep, Rajesh Agarwal, Stanley H. Faeth, Nadja B. Cech, and Nicholas H. Oberlies Mycology, 2015, 6, 8-27. PMID: 26000195; PMCID: PMC4409047; doi:10.1080/21501203.2015.1009186 |
| 115 |
“Ω-Hydroxyemodin Limits Staphylococcus aureus Quorum Sensing-Mediated Pathogenesis and Inflammation.”Seth M. Daly, Bradley O. Elmore, Jeffrey S. Kavanaugh, Kathleen D. Triplett, Mario Figueroa, Huzefa A. Raja, Tamam El-Elimat, Heidi A. Crosby, Jon K. Femling, Nadja B. Cech, Alexander R. Horswill, Nicholas H. Oberlies, and Pamela R. Hall Antimicrobial Agents and Chemotherapy, 2015, 59, 2223-2235. PMID: 25645827; PMCID: PMC4356798; doi: 10.1128/AAC.04564-14 |
| 114 |
“Comparison of the Chemistry and Diversity of Endophytes Isolated from Wild-Harvested and Greenhouse-Cultivated Yerba mansa (Anemopsis californica).”Robert O. Bussey III, Amninder Kaur, Daniel A. Todd, Joseph M. Egan, Tamam El-Elimat, Tyler N. Graf, Huzefa A. Raja, Nicholas H. Oberlies, and Nadja B. Cech Phytochemistry Letters, 2015, 11, 202-208. PMID: 25642298; PMCID: PMC4307022; doi:10.1016/j.phytol.2014.12.013 |
| 113 |
“Sorbicillinoid Analogs with Cytotoxic and Selective Anti-Aspergillus Activities fromScytalidium album.”Tamam El-Elimat, Huzefa A. Raja, Mario Figueroa, Steven M. Swanson, Joseph O. Falkinham III, David M. Lucas, Michael R. Grever, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies The Journal of Antibiotics, 2015, 68, 191-196. PMID: 25248727; PMCID: PMC4372511; doi: 10.1038/ja.2014.125 |
| 112 |
“Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris.”Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Tyler N. Graf, Steven M. Swanson, Joseph O. Falkinham, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies European Journal of Organic Chemistry, 2015, 2015, 109-121. PMID: 25574154; PMCID: PMC4283843; doi: 10.1002/ejoc.201402984 |
| 111 |
“Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance.”John T. Barr, Jeffrey P. Jones, Nicholas H. Oberlies, and Mary F. Paine Drug Metabolism and Disposition, 2015, 43, 34-41. PMID: 25326286; PMCID: PMC4279085; doi: 10.1124/dmd.114.061192 |
2014
| 110 |
“Mass Spectrometry Imaging of Secondary Metabolites Directly on Fungal Cultures.”Vincent P. Sica, Huzefa A. Raja, Tamam El-Elimat, and Nicholas H. Oberlies RSC Advances, 2014, 4, 63221-63227. |
| 109 |
“Identification of Diet-Derived Constituents as Potent Inhibitors of Intestinal Glucuronidation.”Brandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies, and Mary F. Paine Drug Metabolism and Disposition, 2014, 42, 1675-1683. PMID: 25008344; PMCID: PMC4164973; doi: 10.1124/dmd.114.059451 |
| 108 |
“Greensporones: Resorcylic Acid Lactones from an Aquatic Halenospora Sp.”Tamam El-Elimat, Huzefa A. Raja, Cynthia S. Day, Wei-Lun Chen, Steven M. Swanson, and Nicholas H. Oberlies Journal of Natural Products, 2014, 77, 2088-2098. PMID: 25093280; PMCID: PMC4176394; doi: 10.1021/np500497r |
| 107 |
“Bioactive Withanolides from Withania obtusifolia.”Feras Q. Alali, Chiraz Soumia M. Amrine, Tamam El-Elimat, Ahmad Alkofahi, Khaled Tawaha, Mohammad Gharaibah, Steven M. Swanson, Joseph O. Falkinham III, Marisa Cabeza, Araceli Sánchez, Mario Figueroa, and Nicholas H. Oberlies Phytochemistry Letters, 2014, 9, 96-101. |
| 106 |
“Antimycobacterial Furofuran Lignans from the Roots of Anemopsis californica.”Robert O. Bussey III, Arlene A. Sy-Cordero, Mario Figueroa, Fredrick S. Carter, Joseph O. Falkinham III, Nicholas H. Oberlies, and Nadja B. Cech Planta Medica, 2014, 80, 498-501. PMID: 24687738; PMCID: PMC4586282; doi: 10.1055/s-0034-1368352 |
| 105 |
“Labeled Content of Two Furanocoumarins in Dietary Supplements Correlates with Neither Actual Content nor CYP3A Inhibitory Activity.”Karen M. VanderMolen, Garrett R. Ainslie, Mary F. Paine, and Nicholas H. Oberlies Journal of Pharmaceutical and Biomedical Analysis, 2014, 98, 260-265. PMID: 24951959; PMCID: PMC4180667; doi: 10.1016/j.jpba.2014.05.038 |
| 104 |
“Identification of Isosilybin A from Milk Thistle Seeds as an Agonist of Peroxisome Proliferator-Activated Receptor Gamma.”Eva-Maria Pferschy-Wenzig, Atanas G. Atanasov, Clemens Malainer, Stefan M. Noha, Olaf Kunert, Daniela Schuster, Elke H. Heiss, Nicholas H. Oberlies, Hildebert Wagner, Rudolf Bauer, and Verena M. Dirsch Journal of Natural Products, 2014, 77, 842-847. PMID: 24597776; PMCID: PMC4003856; doi: 10.1021/np400943b |
| 103 |
“Epigenetic Manipulation of a Filamentous Fungus by the Proteasome-Inhibitor Bortezomib Induces the Production of an Additional Secondary Metabolite.”Karen M. VanderMolen, Blaise A. Darveaux, Wei-Lun Chen, Steven M. Swanson, Cedric J. Pearce, and Nicholas H. Oberlies RSC advances, 2014, 4, 18329-18335. PMID: 24955237; PMCID: PMC4061710; doi: 10.1039/c4ra00274a |
| 102 |
“Polyhydroxyanthraquinones as Quorum Sensing Inhibitors from the Guttates of Penicilliumrestrictum and Their Analysis by Desorption Electrospray Ionization Mass Spectrometry.”Mario Figueroa, Alan K. Jarmusch, Huzefa A. Raja, Tamam El-Elimat, Jeffrey S. Kavanaugh, Alexander R. Horswill, R. Graham Cooks, Nadja B. Cech, and Nicholas H. Oberlies Journal of Natural Products, 2014, 77, 1351-1358. PMID: 24911880; PMCID: PMC4073659; doi: 10.1021/np5000704 |
| 101 |
“Isochromenones, Isobenzofuranone, and Tetrahydronaphthalenes Produced by Paraphoma radicina, a Fungus Isolated from a Freshwater Habitat.”Tamam El-Elimat, Huzefa A. Raja, Mario Figueroa, Joseph O. Falkinham III, and Nicholas H. Oberlies Phytochemistry, 2014, 104, 114-120. |
| 100 |
“Flavonolignans from Aspergillus iizukae, a Fungal Endophyte of Milk Thistle (Silybum marianum).”Tamam El-Elimat, Huzefa A. Raja, Tyler N. Graf, Stanley H. Faeth, Nadja B. Cech, and Nicholas H. Oberlies Journal of Natural Products, 2014, 77, 193-199. PMID: 24456525; doi: 10.1021/np400955q |
| 99 |
“Physiologically Based Pharmacokinetic Modeling Framework for Quantitative Prediction of an Herb-Drug Interaction.”Scott J. Brantley, Brandon T. Gufford, R Dua, Daryl J. Fediuk, Tyler N. Graf, Yolanda V. Scarlett, Kosea S. Frederick, Matthew B. Fisher, Nicholas H. Oberlies, and Mary F. Paine CPT: Pharmacometrics & Systems Pharmacology, 2014, 3, e107. PMID: 24670388; PMCID: PMC4042458; doi: 10.1038/psp.2013.69 |
2013
| 98 |
“Evaluation of Culture Media for the Production of Secondary Metabolites in a Natural Products Screening Program.”Karen M. VanderMolen, Huzefa A. Raja, Tamam El-Elimat, and Nicholas H. Oberlies AMB Express, 2013, 3, 71. PMID: 24342059; PMCID: PMC3917616; doi: 10.1186/2191-0855-3-71 |
| 97 |
“High-Resolution MS, MS/MS, and UV Database of Fungal Secondary Metabolites as a Dereplication Protocol for Bioactive Natural Products.”Tamam El-Elimat, Mario Figueroa, Brandie M. Ehrmann, Nadja B. Cech, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Natural Products, 2013, 76, 1709-1716. PMID: 23947912; PMCID: PMC3856222; doi: 10.1021/np4004307 |
| 96 |
“Silibinin Inhibits Hepatitis C Virus Entry into Hepatocytes by Hindering Clathrin-Dependent Trafficking.”Julie Blaising, Pierre L. Lévy, Claire Gondeau, Capucine Phelip, Mihayl Varbanov, Elodie Teissier, Florence Ruggiero, Stephen J. Polyak, Nicholas H. Oberlies, Tijana Ivanovic, Steeve Boulant, and Eve-Isabelle Pécheur Cellular Microbiology, 2013, 15, 1866-1882. PMID: 23701235; doi: 10.1111/cmi.12155 |
| 95 |
“Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice Using Ultra-Performance Liquid Chromatography.”Karen M. VanderMolen, Nadja B. Cech, Mary F. Paine, and Nicholas H. Oberlies Phytochemical Analysis, 2013, 24, 654-660. PMID: 23780830; PMCID: PMC3855432; doi: 10.1002/pca.2449 |
| 94 |
“A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice–Fexofenadine Interaction: An in Vitro–in Vivo “Connect”.”Christina S. Won, Tian Lan, Karen M. VanderMolen, Paul A. Dawson, Nicholas H. Oberlies, Wilbur W. Widmer, Yolanda V. Scarlett, and Mary F. Paine The Journal of Clinical Pharmacology, 2013, 53, 982-990. PMID: 23878024; PMCID: PMC4029847; doi: 10.1002/jcph.136 |
| 93 |
“Waol A, Trans-Dihydrowaol A, and Cis-Dihydrowaol A: Polyketide-Derived Γ-Lactones from aVolutella Species.”Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Audrey F. Adcock, David J. Kroll, Steven M. Swanson, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies Tetrahedron Letters, 2013, 54, 4300-4302. PMID: 23956472; PMCID: PMC3743556; doi: 10.1016/j.tetlet.2013.06.008 |
| 92 |
“Peptaibols, Tetramic Acid Derivatives, Isocoumarins, and Sesquiterpenes from a Bionectria Sp. (MSX 47401).”Mario Figueroa, Huzefa Raja, Joseph O. Falkinham, Audrey F. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Natural Products, 2013, 76, 1007-1015. PMID: 23806109; PMCID: PMC3736820; doi: 10.1021/np3008842 |
| 91 |
“Mechanistic Study of the Biomimetic Synthesis of Flavonolignan Diastereoisomers in Milk Thistle.”Hanan S. Althagafy, Maria Elena Meza-Aviña, Nicholas H. Oberlies, and Mitchell P. Croatt The Journal of Organic Chemistry, 2013, 78, 7594-7600. PMID: 23876147; PMCID: PMC3855429; doi: 10.1021/Jo401137 |
| 90 |
“A Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A Inhibitors.”Scott J. Brantley, Tyler N. Graf, Nicholas H. Oberlies, and Mary F. Paine Drug Metabolism and Disposition, 2013, 41, 1662-1670. PMID: 23801821; PMCID: PMC3876807; doi: 10.1124/dmd.113.052563 |
| 89 |
“Semisynthesis, Cytotoxicity, Antiviral Activity, and Drug Interaction Liability of 7-O-Methylated Analogues of Flavonolignans from Milk Thistle.”Hanan S. Althagafy, Tyler N. Graf, Arlene A. Sy-Cordero, Brandon T. Gufford, Mary F. Paine, Jessica Wagoner, Stephen J. Polyak, Mitchell P. Croatt, and Nicholas H. Oberlies Bioorganic & Medicinal Chemistry, 2013, 21, 3919-3926. PMID: 23673225; PMCID: PMC3855444; doi: 10.1016/j.bmc.2013.04.017 |
| 88 |
“HiFSA Fingerprinting Applied to Isomers with near-Identical NMR Spectra: The Silybin/Isosilybin Case.”José G. Napolitano, David C. Lankin, Tyler N. Graf, J. Brent Friesen, Shao-Nong Chen, James B. McAlpine, Nicholas H. Oberlies, and Guido F. Pauli Journal of Organic Chemistry, 2013, 78, 2827-2839. PMID: 23461697; PMCID: PMC3640553; doi: 10.1021/jo302720h |
| 87 |
“Benzoquinones and Terphenyl Compounds as Phosphodiesterase-4B Inhibitors from a Fungus of the Order Chaetothyriales (MSX 47445).”Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Cynthia S. Day, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies Journal of Natural Products, 2013, 76, 382-387. PMID: 23301853; PMCID: PMC3606633; doi: 10.1021/np300749w |
| 86 |
“Silymarin for HCV Infection.”Stephen J. Polyak, Nicholas H. Oberlies, Eve-Isabelle Pécheur, Harel Dahari, Peter Ferenci, and Jean-Michel Pawlotsky Antiviral Therapy, 2013, 18, 141-147. PMID: 23011959; PMCID: PMC4076489; doi: 10.3851/imp2402 |
| 85 |
“Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides.”Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies, and Kim L. R. Brouwer Drug Metabolism and Disposition, 2013, 41, 958-965. PMID: 23401473; PMCID: PMC3629808; doi: 10.1124/dmd.112.048272 |
| 84 |
“Sarothrin from Alkanna Orientalis Is an Antimicrobial Agent and Efflux Pump Inhibitor.”Jessica R. Bame, Tyler N. Graf, Hiyas A. Junio, R. Owen Bussey, Scott A. Jarmusch, Tamam El-Elimat, Joseph O. Falkinham, Nicholas H. Oberlies, Richard A. Cech, and Nadja B. Cech Planta Medica, 2013, 79, 327-329. PMID: 23468310; PMCID: PMC4527991; doi: 10.1055/s-0032-1328259 |
| 83 |
“Enhanced Bioactivity of Silybin B Methylation Products.”Arlene A. Sy-Cordero, Tyler N. Graf, Scott P. Runyon, Mansukh C. Wani, David J. Kroll, Rajesh Agarwal, Scott J. Brantley, Mary F. Paine, Stephen J. Polyak, and Nicholas H. Oberlies Bioorganic & Medicinal Chemistry, 2013, 21, 742-747. PMID: 23260576; PMCID: PMC3630461; doi: 10.1016/j.bmc.2012.11.035 |
| 82 |
“Freshwater Ascomycetes: Minutisphaera (Dothideomycetes) revisited, including one new species from Japan.”Huzefa Raja, Kazuaki Tanaka, Kazuyuki Hirayama, Akira Hoshimoto, Nicholas H. Oberlies, Mario Figueroa, Andrew N. Miller, Steven E. Zelski, and Carol A. Shearer. Mycologia, 2013, 105, 959-976. PMID: 23709484; doi: 10.3852/12-313 |
| 81 |
“Lindgomyces angustiascus, (Lindgomycetaceae, Pleosporales, Dothideomycetes), a new lignicolous species from freshwater habitats in the USA”Huzefa Raja, Nicholas H. Oberlies, Tamama El Elimat, Andrew N. Miller, Steve Zelski, and Carol A. Shearer. Mycoscience, 2013, 54, 353-361. |
2012
| 80 |
“Absolute Configuration of Isosilybin a by X-Ray Crystallography of the Heavy Atom Analogue 7-(4-Bromobenzoyl)Isosilybin A.”Arlene A. Sy-Cordero, Cynthia S. Day, and Nicholas H. Oberlies Journal of Natural Products, 2012, 75, 1879-1881. PMID: 23116206; PMCID: PMC3620721; doi: 10.1021/np3005369 |
| 79 |
“Cytotoxic Epipolythiodioxopiperazine Alkaloids from Filamentous Fungi of the Bionectriaceae.” |
| 78 |
“Revisiting the Enniatins: A Review of Their Isolation, Biosynthesis, Structure Determination and Biological Activities.” |
| 77 |
“Use of the Hollow Fiber Assay for the Discovery of Novel Anticancer Agents from Fungi.” |
| 76 |
“Mechanisms Underlying Food–Drug Interactions: Inhibition of Intestinal Metabolism and Transport.” |
| 75 |
“Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling.” |
| 74 |
“Peptaibols from Two Unidentified Fungi of the Order Hypocreales with Cytotoxic, Antibiotic, and Anthelmintic Activities.” |
| 73 |
“Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents.” |
| 72 |
“Effects of (5z)-7-Oxozeaenol on MDA-MB-231 Breast Cancer Cells.” |
| 71 |
“Effects of (5z)-7-Oxozeaenol on the Oxidative Pathway of Cancer Cells.” |
| 70 |
“Cytotoxic Xanthone-Anthraquinone Heterodimers from an Unidentified Fungus of the Order Hypocreales (MSX 17022).” |
2011
| 69 |
“Thielavin B Methyl Ester: A Cytotoxic Benzoate Trimer from an Unidentified Fungus (MSX 55526) from the Order Sordariales.” |
| 68 |
“Differential in Vitro Effects of Intravenous Versus Oral Formulations of Silibinin on the HCV Life Cycle and Inflammation.” |
| 67 |
“Resorcylic Acid Lactones with Cytotoxic and NF-kB Inhibitory Activities and Their Structure-Activity Relationships.” |
| 66 |
“Isolation and Identification of Intestinal CYP3A Inhibitors from Cranberry (Vaccinium macrocarpon) Using Human Intestinal Microsomes.” |
| 65 |
“Synergy-Directed Fractionation of Botanical Medicines: A Case Study with Goldenseal (Hydrastis canadensis).” |
| 64 |
“Obionin B: An O-Pyranonaphthoquinone Decaketide from an Unidentified Fungus (MSX 63619) from the Order Pleosporales.” |
| 63 |
“Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320).” “Correction to Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320).” |
| 62 |
“Fingolimod (FTY720): A Recently Approved Multiple Sclerosis Drug Based on a Fungal Secondary Metabolite.” |
| 61 |
“Romidepsin (Istodax, NSC 630176, FR901228, FK228, Depsipeptide): A Natural Product Recently Approved for Cutaneous T-Cell Lymphoma.” |
2010
| 60 |
“The Warfarin-Cranberry Juice Interaction Revisited: A Systematic in Vitro-in Vivo Evaluation.” |
| 59 |
“Colchicinoids from Colchicum Crocifolium Boiss. (Colchicaceae).” |
| 58 |
“A Randomized, Controlled, Double-Blind, Pilot Study of Milk Thistle for the Treatment of Hepatotoxicity in Childhood Acute Lymphoblastic Leukemia (ALL).” |
| 57 |
“Dereplication of Macrocyclic Trichothecenes from Extracts of Filamentous Fungi through UV and NMR Profiles.” |
| 56 |
“Multiple Effects of Silymarin on the Hepatitis C Virus Lifecycle.” |
| 55 |
“Identification of Hepatoprotective Flavonolignans from Silymarin.” |
| 54 |
“Two Flavonolignans from Milk Thistle (Silybum marianum) Inhibit CYP2C9-Mediated Warfarin Metabolism at Clinically Achievable Concentrations.” |
| 53 |
“Large-Scale Isolation of Flavonolignans from Silybum marianum Extract Affords New Minor Constituents and Preliminary Structure-Activity Relationships.” |
| 52 |
“Isosilybin A Induces Apoptosis in Human Prostate Cancer Cells Via Targeting Akt, NF-kappaB, and Androgen Receptor Signaling.” |
| 51 |
“Silymarin Inhibits in Vitro T Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection.” |
| 50 |
“Influence of Dietary Substances on Intestinal Drug Metabolism and Transport.” |
2009
| 49 |
“Mapping of Sample Collection Data: Gis Tools for the Natural Product Researcher.” |
| 48 |
“Identification of a Cranberry Juice Product That Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans.” |
| 47 |
“Proliferation of Antibiotic Producing Bacteria and Concomitant Antibiotic Production as the Basis for the Antibiotic Activity of Jordan’s Red Soils.” |
| 46 |
“Bioactive Constituents of the Stem Bark of Mitrephora Glabra.” |
| 45 |
“Discovery of Anticancer Agents of Diverse Natural Origin.” |
2008
| 44 |
“Microbial-Mediated Release of Bisphenol A from Polycarbonate Vessels.” |
| 43 |
“Colchicinoids from Colchicum Crocifolium Boiss.: A Case Study in Dereplication Strategies for (-)-Colchicine and Related Analogs Using LC-MS and LC-PDA Techniques.” |
| 42 |
“Isosilibinin Inhibits Advanced Human Prostate Cancer Growth in Athymic Nude Mice: Comparison with Silymarin and Silibinin.” |
| 41 |
“Identifying the Differential Effects of Silymarin Constituents on Cell Growth and Cell Cycle Regulatory Molecules in Human Prostate Cancer Cells.” |
| 40 |
“Isosilybin B Causes Androgen Receptor Degradation in Human Prostate Carcinoma Cells Via PI3K-Akt-Mdm2-Mediated Pathway.” |
| 39 |
“Pyrrolizidine Alkaloids from Echium glomeratum (Boraginaceae).” |
2007
| 38 |
“A Novel Small Molecule That Selectively Inhibits Glioblastoma Cells Expressing EGFRvIII.” |
| 37 |
“Antioxidant Activity and Total Phenolic Content of Aqueous and Methanolic Extracts of Jordanian Plants: An ICBG Project.” |
| 36 |
“Isosilybin B and Isosilybin A Inhibit Growth, Induce G1 Arrest and Cause Apoptosis in Human Prostate Cancer LNCaP and 22Rv1 Cells.” |
| 35 |
“Development of a Fluorescence-Based Assay to Screen Antiviral Drugs against Kaposi’s Sarcoma Associated Herpesvirus.” |
| 34 |
“Variability in the Yield of Benzophenanthridine Alkaloids in Wildcrafted vs Cultivated Bloodroot (Sanguinaria canadensis L.).” |
| 33 |
“Alvaradoins E-N, Antitumor and Cytotoxic Anthracenone C-Glycosides from the Leaves of Alvaradoa haitiensis.” |
| 32 |
“Gram-Scale Purification of Flavonolignan Diastereoisomers from Silybum marianum (Milk Thistle) Extract in Support of Preclinical in Vivo Studies for Prostate Cancer Chemoprevention.” |
| 31 |
“Milk Thistle Nomenclature: Why It Matters in Cancer Research and Pharmacokinetic Studies.” |
| 30 |
“Clinical Relevance of the Small Intestine as an Organ of Drug Elimination: Drug-Fruit Juice Interactions.” |
2006
| 29 |
“A New Colchicinoid from Colchicum tauri, an Unexplored Meadow Saffron Native to Jordan.” |
| 28 |
“Phytochemical Studies and Cytotoxicity Evaluations of Colchicum tunicatum Feinbr and Colchicum hierosolymitanum Feinbr (Colchicaceae): Two Native Jordanian Meadow Saffrons.” |
| 27 |
“Dendrimer-Encapsulated Camptothecins: Increased Solubility, Cellular Uptake, and Cellular Retention Affords Enhanced Anticancer Activity in Vitro.” |
| 26 |
“Simple and Inexpensive Methods to Prevent Botanical Misfortune.” |
2005
| 25 |
“New Colchicinoids from a Native Jordanian Meadow Saffron, Colchicum brachyphyllum: Isolation of the First Naturally Occurring Dextrorotary Colchicinoid.” Feras Q. Alali, Tamam El-Elimat, Chen Li, Amjad Qandil, Ahmad Alkofahi, Khaled Tawaha, Jason P. Burgess, Yuka Nakanishi, David J. Kroll, Hernán A. Navarro, III Joseph O. Falkinham III, Mansukh C. Wani, and Nicholas H. Oberlies Journal of Natural Products, 2005, 68, 173-178. PMID: 15730238; doi: 10.1021/np0496587 |
| 24 |
“Diterpene Glycosides from Egletes viscosa.” Dongho Lee, Chen Li, Tyler N. Graf, Jose Schunke Vigo, James G. Graham, Fernando Cabieses, Norman R. Farnsworth, Geoffrey A. Cordell, A. Douglas Kinghorn, David J. Kroll, Mansukh C. Wani, and Nicholas H. Oberlies Planta Medica, 2005, 71, 792-794. |
| 23 |
“A Hexacyclic Ent-Trachylobane Diterpenoid Possessing an Oxetane Ring from Mitrephora Glabra.” Chen Li, Dongho Lee, Tyler N. Graf, Sharnelle S. Phifer, Yuka Nakanishi, Jason P. Burgess, Soedarsono Riswan, Fransisca M. Setyowati, Achmad M. Saribi, Djaja D. Soejarto, Norman R. Farnsworth, Joseph O. Falkinham III, David J. Kroll, A. Douglas Kinghorn, Mansukh C. Wani, and Nicholas H. Oberlies Organic Letters, 2005, 7, 5709-5712. PMID: 16321028; PMCID: PMC2442714; doi: 10.1021/ol052498l |
| 22 |
“Milk Thistle and Prostate Cancer: Differential Effects of Pure Flavonolignans from Silybum marianum on Antiproliferative End Points in Human Prostate Carcinoma Cells.” Paula R. Davis-Searles, Yuka Nakanishi, Nam-Cheol Kim, Tyler N. Graf, Nicholas H. Oberlies, Mansukh C. Wani, Monroe E. Wall, Rajesh Agarwal, and David J. Kroll Cancer Research, 2005, 65, 4448-4457. |
| 21 |
“The Most Widely Recognized Mushroom: Chemistry of the Genus Amanita.” Chen Li, and Nicholas H. Oberlies Life Sciences, 2005, 78, 532-538. |
2004
| 20 |
“Analysis of Herbal Teas Made from the Leaves of Comfrey (Symphytum officinale): Reduction of N-Oxides Results in Order of Magnitude Increases in the Measurable Concentration of Pyrrolizidine Alkaloids.” Nicholas H Oberlies, Nam-Cheol Kim, Dolores R Brine, Bradley J Collins, Robert W Handy, Charles M Sparacino, Mansukh C Wani, and Monroe E Wall Public Health Nutrition, 2004, 7, 919-924. PMID: 15482618; doi: 10.1079/PHN2004624 |
| 19 |
“Cytotoxic and Antimicrobial Constituents of the Bark of Diospyros maritima Collected in Two Geographical Locations in Indonesia.” Jian-Qiao Gu, Tyler N. Graf, Dongho Lee, Hee-Byung Chai, Qiuwen Mi, Leonardus B. S. Kardono, Fransisca M. Setyowati, Rachman Ismail, Soedarsono Riswan, Norman R. Farnsworth, Geoffrey A. Cordell, John M. Pezzuto, Steven M. Swanson, David J. Kroll, Joseph O. Falkinham III, Monroe E. Wall, Mansukh C. Wani, A. Douglas Kinghorn, and Nicholas H. Oberlies Journal of Natural Products, 2004, 67, 1156-1161. PMID: 15270571; doi: 10.1021/np040027m |
| 18 |
“Camptothecin and Taxol: Historic Achievements in Natural Products Research.” Nicholas H. Oberlies, and David J. Kroll Journal of Natural Products, 2004, 67, 129-135. PMID: 14987046; doi: 10.1021/np030498t |
2003
| 17 |
“Synergistic Antimicrobial Activity of Metabolites Produced by a Nonobligate Bacterial Predator.” Cody C. Cain, Dongho Lee, Robert H. Waldo III, Alexis T. Henry, Earl J. Casida Jr., Mansukh C. Wani, Monroe E. Wall, Nicholas H. Oberlies, and Joseph O. Falkinham III Antimicrobial Agents and Chemotherapy, 2003, 47, 2113-2117. PMID: 12821455; PMCID: PMC161883; doi: 10.1128/AAC.47.7.2113-2117.2003 |
| 16 |
“Novel Strategies for the Discovery of Plant-Derived Anticancer Agents.”A. Kinghorn, Norman Farnsworth, Djaja Soejarto, Geoffrey Cordell, Steven Swanson, John Pezzuto, Mansukh Wani, Monroe Wall, Nicholas Oberlies, David Kroll, Robert Kramer, William Rose, Gregory Vite, Craig Fairchild, Russell Peterson, and Robert Wild Pharmaceutical Biology, 2003, 41 (Suppl.), 53-67. |
2002
| 15 |
“Novel Bioactive Clerodane Diterpenoids from the Leaves and Twigs of Casearia sylvestris.”Nicholas H. Oberlies, Jason P. Burgess, Hernán A. Navarro, Rosa Elena Pinos, Craig R. Fairchild, Russell W. Peterson, Djaja D. Soejarto, Norman R. Farnsworth, A. Douglas Kinghorn, Mansukh C. Wani, and Monroe E. Wall Journal of Natural Products, 2002, 65, 95-99. PMID: 11858737; doi: 10.1021/np010459m |
2001
| 14 |
“Bioactive Constituents of the Roots of Licania intrapetiolaris.”Nicholas H. Oberlies, Jason P. Burgess, Hernán A. Navarro, Rosa Elena Pinos, Djaja D. Soejarto, Norman R. Farnsworth, A. Douglas Kinghorn, Mansukh C. Wani, and Monroe E. Wall Journal of Natural Products, 2001, 64, 497-501. PMID: 11325234; doi: 10.1021/np0005006 |
| 13 |
“Isolation of Symlandine from the Roots of Common Comfrey (Symphytum officinale) Using Countercurrent Chromatography.”Nam-Cheol Kim, Nicholas H. Oberlies, Dolores R. Brine, Robert W. Handy, Mansukh C. Wani, and Monroe E. Wall Journal of Natural Products, 2001, 64, 251-253. PMID: 11430014; doi: 10.1021/np0004653 |
1998
| 12 |
“Cytotoxic and Insecticidal Constituents of the Unripe Fruit of Persea americana.”Nicholas H. Oberlies, Lingling L. Rogers, John M. Martin, and Jerry L. McLaughlin Journal of Natural Products, 1998, 61, 781-785. PMID: 9644064; doi: 10.1021/np9800304 |
| 11 |
“Myosin Isoform Shifts and Decreased Reactivity in Hypoxia-Induced Hypertensive Pulmonary Arterial Muscle.”C. Subah Packer, Janet E. Roepke, Nicholas H. Oberlies, and Rodney A. Rhoades American Journal of Physiology, 1998, 274, L775-L785. PMID: 9612293; doi: 10.1152/ajplung.1998.274.5.L775 |
1997
| 10 |
“The Annonaceous Acetogenin Bullatacin Is Cytotoxic against Multidrug Resistant Human Mammary Adenocarcinoma Cells.”Nicholas H. Oberlies, Vicki L. Croy, Marietta L. Harrison, and Jerry L. McLaughlin Cancer Letters, 1997, 115, 73-79. |
| 9 |
“Comparative SAR Evaluations of Annonaceous Acetogenins for Pesticidal Activity.”Kan He, Lu Zeng, Qing Ye, Guoen Shi, Nicholas H. Oberlies, Geng-Xian Zhao, C. Jesse Njoku, and Jerry L. McLaughlin Pesticide Science, 1997, 49, 372-379. doi: 10.1002/(SICI)1096-9063(199704)49:4<372::AID-PS543>3.0.CO;2-K |
| 8 |
“Oleanolic Acid, a Bioactive Component of the Leaves of Ocimum gratissimum (Lamiaceae).”C.J. Njoku, Lu Zeng, I.U. Asuzu, Nicholas H. Oberlies, and Jerry L. McLaughlin International Journal of Pharmacognosy, 1997, 35, 134-137. |
| 7 |
“Structure-Activity Relationships of Diverse Annonaceous Acetogenins against Multidrug Resistant Human Mammary Adenocarcinoma (MCF-7/Adr) Cells.”Nicholas H. Oberlies, Ching-jer Chang, and Jerry L. McLaughlin Journal of Medicinal Chemistry, 1997, 40, 2102-2106. PMID: 9207950; doi: 10.1021/jm9700169 |
1996
| 6 |
“Longimicins A-D: Novel Bioactive Acetogenins from Asimina longifolia (Annonaceae), and Structure Activity Relationships of Asimicin Type Annonaceous Acetogenins.”Qing Ye, Kan He, Nicholas H. Oberlies, Lu Zeng, Guoen Shi, Dean Evert, and Jerry L. McLaughlin Journal of Medicinal Chemistry, 1996, 39, 1790-1796. PMID: 8627602; doi: 10.1021/jm9600510 |
| 5 |
“Five New Monotetrahydrofuran Ring Acetogenins from the Leaves of Annona muricata.”Lu Zeng, Feng-E Wu, Nicholas H. Oberlies, and Jerry L. McLaughlin Journal of Natural Products, 1996, 59, 1035-1042. PMID: 8946744; doi: 10.1021/np960447e |
| 4 |
“Recent Advances in Annonaceous Acetogenins.”Lu Zeng, Qing Ye, Nicholas H. Oberlies, Guoen Shi, Zhe-Ming Gu, Kan He, and Jerry L. McLaughlin Natural Products Reports, 1996, 13, 275-306. PMID: 8760865; doi: 10.1039/NP9961300275 |
1995
| 3 |
“Tumor Cell Growth Inhibition by Several Annonaceous Acetogenins in an in Vitro Disk Diffusion Assay.”Nicholas H. Oberlies, Julie L. Jones, Thomas H. Corbett, Sophia S. Fotopoulos, and Jerry L. McLaughlin Cancer Letters, 1995, 96, 55-62. |
| 2 |
“Mode of Action of Bullatacin, a Potent Antitumor Acetogenin: Inhibition of NADH Oxidase Activity of HeLa and HL-60, but Not Liver, Plasma Membranes.”D. James Morré, Rafael de Cabo, Christopher Farley, Nicholas H. Oberlies, and Jerry L. McLaughlin Life Sciences, 1995, 56, 343-348. |
1993
| 1 |
“The Electrochemical Preparation and Kinetic and Product Studies of Acylated Quinol and Quinol Ether Imines – in Search of the Hydrolysis Products of the Ultimate Carcinogen of N-Acetyl-2-Aminofluorene.”Michael Novak, John S. Helmick, Nicholas Oberlies, Kanchugarakoppal S. Rangappa, William M. Clark, and John S. Swenton Journal of Organic Chemistry, 1993, 58, 867-878. |
