Publications

2017

153

“Additions to Lindgomyces (Lindgomycetaceae, Pleosporales, Dothideomycetes), Including Two New Species Occurring on Submerged Wood from North Carolina, USA, with Notes on Secondary Metabolite Profiles.”
Huzefa A. Raja, Noemi D. Paguigan, Jacques Fournier, and Nicholas H. Oberlies
Mycological Progress, 2017, 16, 535-552.
doi: 10.1007/s11557-017-1282-4

152

“Safety Assessment of Mushrooms in Dietary Supplements by Combining Analytical Data with in Silico Toxicology Evaluation.”
Karen M. VanderMolen, Jason G. Little, Vincent P. Sica, Tamam El-Elimat, Huzefa A. Raja, Nicholas H. Oberlies, Timothy R. Baker, and Catherine Mahony
Food and Chemical Toxicology, 2017, 103, 133-147.
PMID: 28267567; doi: 10.1016/j.fct.2017.03.005

151

“Plasma Pharmacokinetics and Bioavailability of Verticillin A Following Different Routes of Administration in Mice Using Liquid Chromatography Tandem Mass Spectrometry.”
Jiang Wang, Xiaohua Zhu, Shamala Kolli, Hongyan Wang, Cedric J. Pearce, Nicholas H. Oberlies, and Mitch A. Phelps
Journal of Pharmaceutical and Biomedical Analysis, 2017, 139, 187-192.
PMID: 28284083; PMCID: PMC5399420; doi: 10.1016/j.jpba.2017.02.051

150

“Fungal Identification Using Molecular Tools: A Primer for the Natural Products Research Community.”
Huzefa A. Raja, Andrew N. Miller, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2017, 80, 756-770.
PMID: 28199101; PMCID: PMC5368684; doi: 10.1021/acs.jnatprod.6b01085

149

“DNA Barcoding for Identification of Consumer-Relevant Mushrooms: A Partial Solution for Product Certification?”
Huzefa A. Raja, Timothy R. Baker, Jason G. Little, and Nicholas H. Oberlies
Food Chemistry, 2017, 214, 383-392.
PMID: 27507489; doi: 10.1016/j.foodchem.2016.07.052

148

“Enhanced Dereplication of Fungal Cultures Via Use of Mass Defect Filtering.”
Noemi D. Paguigan, Tamam El-Elimat, Diana Kao, Huzefa A. Raja, Cedric J. Pearce, and Nicholas H. Oberlies
The Journal of Antibiotics, 2017, 70, 553-561.
PMID: 28074050 PMCID; PMC5407915; doi: 10.1038/ja.2016.145

147

 “The MLL1-H3K4me3 Axis-Mediated PD-L1 Expression and Pancreatic Cancer Immune Evasion.”
Chunwan Lu, Amy V. Paschall, Huidong Shi, Natasha Savage, Jennifer L. Waller, Maria E. Sabbatini, Nicholas H. Oberlies, Cedric Pearce, and Kebin Liu
Journal of the National Cancer Institute, 2017, 109, djw283.
PMID: 28131992 PMCID; PMC5291187; doi: 10.1093/jnci/djw283

146

“Scaffold Diversity of Fungal Metabolites.”
Mariana González-Medina, John R. Owen, Tamam El-Elimat, Cedric J. Pearce, Nicholas H. Oberlies, Mario Figueroa, and José L. Medina-Franco
Frontiers in Pharmacology, 2017, 8, 180.
PMID: 28420994; PMCID: PMC5376591; doi: 10.3389/fphar.2017.00180

145

“Nanoparticle Drug-Delivery Systems for Peritoneal Cancers: A Case Study of the Design, Characterization and Development of the Expansile Nanoparticle.”
Aaron H. Colby, Nicholas H. Oberlies, Cedric J. Pearce, Victoria L. M. Herrera, Yolonda L. Colson, and Mark W. Grinstaff
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 2017, 9, e1451-n/a.
PMID: 28185434; PMCID: PMC5389910; doi: 10.1002/wnan.1451

144

a-Pyrone Derivatives, Tetra/Hexahydroxanthones, and Cyclodepsipeptides from Two Freshwater Fungi.”
Tamam El-Elimat, Huzefa A Raja, Cynthia S. Day, Hana McFeeters, Robert L. McFeeters, and Nicholas H. Oberlies
Bioorganic & Medicinal Chemistry, 2017, 25, 795-804.
PMID: 27964996; doi: 10.1016/j.bmc.2016.11.059

Top ↑


2016

143

“Discovery of Anticancer Agents of Diverse Natural Origin.”
Douglas Kinghorn, Esperanza J. Carcache De Blanco, David M. Lucas, H. Liva Rakotondraibe, Jimmy Orjala, D. Doel Soejarto, Nicholas H. Oberlies, Cedric J. Pearce, Mansukh C. Wani, Brent R. Stockwell, Joanna E. Burdette, Steven M. Swanson, James R. Fuchs, Mitchell A. Phelps, Lihui Xu, Xiaoli Zhang, and Young Yongchun Shen
Anticancer Research, 2016, 36, 5623-5637.
PMID: 27793884; PMCID: PMC5098703; doi: 10.21873/anticanres.11146

142

“Chemoinformatic Expedition of the Chemical Space of Fungal Products.”
Mariana González-Medina, Fernando D. Prieto-Martínez, J. Jesús Naveja, Oscar Méndez-Lucio, Tamam El-Elimat, Cedric J. Pearce, Nicholas H. Oberlies, Mario Figueroa, and José L. Medina-Franco
Future Medicinal Chemistry, 2016, 8, 1399-1412.
PMID: 27485744; doi: 10.4155/fmc-2016-0079

141

“Antimicrobial Fungal Endophytes from the Botanical Medicine Goldenseal (Hydrastis canadensis).”
Joseph M. Egan, Amninder Kaur, Huzefa A. Raja, Joshua J. Kellogg, Nicholas H.Oberlies, and Nadja B.Cech
Phytochemistry Letters, 2016, 17, 219-225.
doi: 10.1016/j.phytol.2016.07.031

140

“Secondary Metabolites from Fungal Endophytes of Echinacea purpurea Suppress Cytokine Secretion by Macrophage-Type Cells.”
Amninder Kaur, Martina Oberhofer, Monika Juzumaite, Huzefa A. Raja, Travis V. Gulledge, Diana Kao, Stanley H. Faeth, Scott M. Laster, Nicholas H. Oberlies, and Nadja B. Cech
Natural Product Communications, 2016, 11, 1143-1146.

139

In Situ Analysis of Asimina triloba (Paw Paw) Plant Tissues for Acetogenins via the Droplet-Liquid Microjunction-Surface Sampling Probe Coupled to UHPLC-PDA-HRMS/MS.”
Vincent P .Sica, Tamam El-Elimat, and Nicholas H. Oberlies
Analytical Methods, 2016, 8, 6143-6149.
doi: 10.1039/C6AY01583B

138

“Verticillin A Inhibits Leiomyosarcoma and Malignant Peripheral Nerve Sheath Tumor Growth Via Induction of Apoptosis.”
Abbie Zewdu, Gonzalo Lopez, Danielle Braggio, Connor Kenney, Constantino D, ,, Hemant Bid, Kara Batte, O. Hans Iwenofu, Nicholas H. Oberlies, Cedric J. Pearce, Anne Strohecker, Dina Lev, and Raphael E. Pollock
Clinical and Experimental Pharmacology, 2016, 06.
doi: 10.4172/2161-1459.1000221

137

“Optimizing Production and Evaluating Biosynthesis in Situ of a Herbicidal Compound, Mevalocidin, from Coniolariella Sp.”
Vincent P. Sica, Mario Figueroa, Huzefa A. Raja, Tamam El-Elimat, Blaise A. Darveaux, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Industrial Microbiology & Biotechnology, 2016, 43, 1149-1157.
PMID: 27221133; doi: 10.1007/s10295-016-1782-2

136

“Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages.”
Limei Wang, Susanne Rotter, Angela Ladurner, H. Elke Heiss, H. Nicholas Oberlies, M. Verena Dirsch, and G. Atanas Atanasov
Molecules, 2016, 21, .
PMID: 26729088; PMCID: PMC4748397; doi: 10.3390/molecules21010055

135

“Spatial and Temporal Profiling of Griseofulvin Production in Xylaria cubensis Using Mass Spectrometry Mapping.”
 Vincent Sica, Evan Rees, Edem Tchegnon, Robert Bardsley, Huzefa Raja, and Nicholas Oberlies
Frontiers in Microbiology, 2016, 7.
PMID: 27199902; PMCID: PMC4844619; doi: 10.3389/fmicb.2016.00544

134

“Acetophenone Derivatives from a Freshwater Fungal Isolate of Recently Described Lindgomyces Madisonensis (G416).”
Noemi D. Paguigan, Huzefa A. Raja, Cynthia S. Day, and Nicholas H. Oberlies
Phytochemistry, 2016, 126, 59-65.
PMID: 26988728; doi: 10.1016/j.phytochem.2016.03.007

133

“Biochemometrics for Natural Products Research: Comparison of Data Analysis Approaches and Application to Identification of Bioactive Compounds.”
Joshua J. Kellogg, Daniel A. Todd, Joseph M. Egan, Huzefa A. Raja, Nicholas H. Oberlies, Olav M. Kvalheim, and Nadja B. Cech
Journal of Natural Products, 2016, 79, 376-386.
PMID: 26841051; doi: 10.1021/acs.jnatprod.5b01014

132

“Talarolutins A–D: Meroterpenoids from an Endophytic Fungal Isolate of Talaromyces minioluteus.”
Amninder Kaur, Huzefa A. Raja, Dale C. Swenson, Rajesh Agarwal, Gagan Deep, Joseph O. Falkinham III, and Nicholas H. Oberlies
Phytochemistry, 2016, 126, 4-10.
PMID: 27048854; PMCID: PMC4861051; doi: 10.1016/j.phytochem.2016.03.013

131

“A Validated UHPLC-Tandem Mass Spectrometry Method for Quantitative Analysis of Flavonolignans in Milk Thistle (Silybum marianum) Extracts.”
Tyler N. Graf, Nadja B. Cech, Stephen J. Polyak, and Nicholas H. Oberlies
Journal of Pharmaceutical and Biomedical Analysis, 2016, 126, 26-33.
PMID: 27136284; PMCID: PMC4893890; doi: 10.1016/j.jpba.2016.04.028

130

“Graviola Inhibits Hypoxia-Induced NADPH Oxidase Activity in Prostate Cancer Cells Reducing Their Proliferation and Clonogenicity.”
Gagan Deep, Rahul Kumar, Anil K. Jain, Deepanshi Dhar, Gati K. Panigrahi, Anowar Hussain, Chapla Agarwal, Tamam El-Elimat, Vincent P. Sica, Nicholas H. Oberlies, and Rajesh Agarwal
Scientific Reports, 2016, 6, 23135.
PMID: 26979487; PMCID: PMC4793251; doi: 10.1038/srep23135

129

“Pannorin B, a New Naphthopyrone from an Endophytic Fungal Isolate of Penicillium Sp.”
Amninder Kaur, Huzefa A. Raja, Gagan Deep, Rajesh Agarwal, and Nicholas H. Oberlies
Magnetic Resonance in Chemistry, 2016, 54, 164-167.
PMID: 26365944; doi: 10.1002/mrc.4324

Top ↑


2015

128

“Fungal Planet Description Sheets: 371-399.”
Crous, P. W., Wingfield, M. J., Le Roux, J. J., Richardson, D. M., Strasberg, D., Shivas, R. G., Alvarado, P., Edwards, J., Moreno, G., Sharma, R., Sonawane, M. S., Tan, Y. P., Altes, A., Barasubiye, T., Barnes, C. W., Blanchette, R. A., Boertmann, D., Bogo, A., Carlavilla, J. R., Cheewangkoon, R., Daniel, R., de Beer, Z. W., de Jesus Yanez-Morales, M., Duong, T. A., Fernandez-Vicente, J., Geering, A. D., Guest, D. I., Held, B. W., Heykoop, M., Hubka, V., Ismail, A. M., Kajale, S. C., Khemmuk, W., Kolarik, M., Kurli, R., Lebeuf, R., Levesque, C. A., Lombard, L., Magista, D., Manjon, J. L., Marincowitz, S., Mohedano, J. M., Novakova, A., Oberlies, N. H., Otto, E. C., Paguigan, N. D., Pascoe, I. G., Perez-Butron, J. L., Perrone, G., Rahi, P., Raja, H. A., Rintoul, T., Sanhueza, R. M., Scarlett, K., Shouche, Y. S., Shuttleworth, L. A., Taylor, P. W., Thorn, R. G., Vawdrey, L. L., Solano-Vidal, R., Voitk, A., Wong, P. T., Wood, A. R., Zamora, J. C., and Groenewald, J. Z.
Persoonia, 2015, 35, 264-327.
PMID: 26823636; PMCID: PMC4713108; doi: 10.3767/003158515×690269

127

“H3K9 Trimethylation Silences FASs Expression to Confer Colon Carcinoma Immune Escape and 5-Fluorouracil Chemoresistance.”
Amy V. Paschall, Dafeng Yang, Chunwan Lu, Jeong-Hyeon Choi, Xia Li, Feiyan Liu, Mario Figueroa, Nicholas H. Oberlies, Cedric Pearce, Wendy B. Bollag, Asha Nayak-Kapoor, and Kebin Liu
The Journal of Immunology, 2015, 195, 1868-1882.
PMID: 26136424; PMCID: PMC4530033; doi: 10.4049/jimmunol.1402243

126

“Minutisphaerales (Dothideomycetes, Ascomycota): A New Order of Freshwater Ascomycetes Including a New Family, Minutisphaeraceae, and Two New Species from North Carolina, USA.”
Huzefa A. Raja, Tamam El-Elimat, Nicholas H. Oberlies, Carol A. Shearer, Andrew N. Miller, Kazuaki Tanaka, Akira Hashimoto, and Jacques Fournier
Mycologia, 2015, 107, 845-862.
PMID: 26315030; doi: 10.3852/15-013

125

“Silymarin Suppresses Cellular Inflammation by Inducing Reparative Stress Signaling.”
Erica S. Lovelace, Jessica Wagoner, James MacDonald, Theo Bammler, Jacob Bruckner, Jessica Brownell, Richard P. Beyer, Erika M. Zink, Young-Mo Kim, Jennifer E. Kyle, Bobbie-Jo M. Webb-Robertson, Katrina M. Waters, Thomas O. Metz, Federico Farin, Nicholas H. Oberlies, and Stephen J. Polyak
Journal of Natural Products, 2015, 78, 1990-2000.
PMID: 26186142; PMCID: PMC4703094; doi: 10.1021/acs.jnatprod.5b00288

124

“Isolation, Semisynthesis, Covalent Docking and Transforming Growth Factor Beta-Activated Kinase 1 (TAK1)-Inhibitory Activities of (5Z)-7-Oxozeaenol Analogues.”
Lara Fakhouri, Tamam El-Elimat, Dow P. Hurst, Patricia H. Reggio, Cedric J. Pearce, Nicholas H. Oberlies, and Mitchell P. Croatt
Bioorganic & Medicinal Chemistry, 2015, 23, 6993-6999.
PMID: 26481152; PMCID: PMC4661079; doi: 10.1016/j.bmc.2015.09.037

123

“Milk Thistle Constituents Inhibit Raloxifene Intestinal Glucuronidation: A Potential Clinically Relevant Natural Product–Drug Interaction.”
Brandon T. Gufford, Gang Chen, Ana G. Vergara, Philip Lazarus, Nicholas H. Oberlies, and Mary F. Paine
Drug Metabolism and Disposition, 2015, 43, 1353-1359.
PMID: 26070840; PMCID: PMC4538855; doi: 10.1124/dmd.115.065086

122

“Chemoenzymatic Synthesis, Characterization, and Scale-up of Milk Thistle Flavonolignan Glucuronides.”
Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies, and Mary F. Paine
Drug Metabolism and Disposition, 2015, 43, 1734-1743.
PMID: 26316643; PMCID: PMC4613946; doi: 10.1124/dmd.115.066076

121

“Spiroscytalin, a New Tetramic Acid and Other Metabolites of Mixed Biogenesis fromScytalidium cuboideum.”
Arlene A. Sy-Cordero, Mario Figueroa, Huzefa A. Raja, Maria Elena Meza Aviña, Mitchell P. Croatt, Audrey F. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Tetrahedron, 2015, 71, 8899-8904.
PMID: 26525642; PMCID: PMC4624200; doi: 10.1016/j.tet.2015.09.073

120

“Cytotoxic Homoisoflavones from the Bulbs of Bellevalia eigii.”
Feras Q. Alali, Tamam El-Elimat, Hanan Albataineh, Qosay Al-Balas, Mohammad Al-Gharaibeh, Joseph O. Falkinham, Wei-Lun Chen, Steven M. Swanson, and Nicholas H. Oberlies
Journal of Natural Products, 2015, 78, 1708-1715.
PMID: 26147490; PMCID: PMC4615712; doi: 10.1021/acs.jnatprod.5b00357

119

“New Diketopiperazine Dimer from a Filamentous Fungal Isolate of Aspergillus sydowii.”
Amninder Kaur, Huzefa A. Raja, Blaise A. Darveaux, Wei-Lun Chen, Steven M. Swanson, Cedric J. Pearce, and Nicholas H. Oberlies
Magnetic Resonance in Chemistry, 2015, 53, 616-619.
PMID: 26040447; PMCID: PMC4692248; doi: 10.1002/mrc.4254

118

“Dereplicating and Spatial Mapping of Secondary Metabolites from Fungal Cultures in Situ.”
Vincent P .Sica, Huzefa A. Raja, Tamam El-Elimat, Vilmos Kertesz, Gary J.Van Berkel, Cedric J.Pearce, and Nicholas H.Oberlies
Journal of Natural Products, 2015, 78, 1926-1936.
PMID: 26192135; PMCID: PMC4570219; doi: 10.1021/acs.jnatprod.5b00268

117

“Ethanolic Echinacea purpurea Extracts Contain a Mixture of Cytokine-Suppressive and Cytokine-Inducing Compounds, Including Some That Originate from Endophytic Bacteria.”
Daniel A. Todd, Travis V. Gulledge, Emily R. Britton, Martina Oberhofer, Martha Leyte-Lugo, Ashley N. Moody, Tatsiana Shymanovich, Laura F. Grubbs, Monika Juzumaite, Tyler N. Graf, Nicholas H. Oberlies, Stanley H. Faeth, Scott M. Laster, and Nadja B. Cech
Plos One, 2015, 10, e0124276.
PMID: 25933416; doi: 10.1371/journal.pone.0124276

116

“Phylogenetic and Chemical Diversity of Fungal Endophytes Isolated from Silybum marianum(L) Gaertn. (Milk Thistle).”
Huzefa A. Raja, Amninder Kaur, Tamam El-Elimat, Mario Figueroa, Rahul Kumar, Gagan Deep, Rajesh Agarwal, Stanley H. Faeth, Nadja B. Cech, and Nicholas H. Oberlies
Mycology, 2015, 6, 8-27.
doi:10.1080/21501203.2015.1009186

115

“Ω-Hydroxyemodin Limits Staphylococcus aureus Quorum Sensing-Mediated Pathogenesis and Inflammation.”
Seth M. Daly, Bradley O. Elmore, Jeffrey S. Kavanaugh, Kathleen D. Triplett, Mario Figueroa, Huzefa A. Raja, Tamam El-Elimat, Heidi A. Crosby, Jon K. Femling, Nadja B. Cech, Alexander R. Horswill, Nicholas H. Oberlies, and Pamela R. Hall
Antimicrobial Agents and Chemotherapy, 2015, 59, 2223-2235.
PMID: 25645827; PMCID: PMC4356798; doi: 10.1128/AAC.04564-14

114

“Comparison of the Chemistry and Diversity of Endophytes Isolated from Wild-Harvested and Greenhouse-Cultivated Yerba mansa (Anemopsis californica).”
Robert O. Bussey III, Amninder Kaur, Daniel A. Todd, Joseph M. Egan, Tamam El-Elimat, Tyler N. Graf, Huzefa A. Raja, Nicholas H. Oberlies, and Nadja B. Cech
Phytochemistry Letters, 2015, 11, 202-208.
PMID: 25642298; PMCID: PMC4307022; doi:10.1016/j.phytol.2014.12.013

113

“Sorbicillinoid Analogs with Cytotoxic and Selective Anti-Aspergillus Activities fromScytalidium album.”
Tamam El-Elimat, Huzefa A. Raja, Mario Figueroa, Steven M. Swanson, Joseph O. Falkinham III, David M. Lucas, Michael R. Grever, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
The Journal of Antibiotics, 2015, 68, 191-196.
PMID: 25248727; PMCID: PMC4372511; doi: 10.1038/ja.2014.125

112

“Biosynthetically Distinct Cytotoxic Polyketides from Setophoma terrestris.”
Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Tyler N. Graf, Steven M. Swanson, Joseph O. Falkinham, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
European Journal of Organic Chemistry, 2015, 2015, 109-121.
PMID: 25574154; PMCID: PMC4283843; doi: 10.1002/ejoc.201402984

111

“Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance.”
John T. Barr, Jeffrey P. Jones, Nicholas H. Oberlies, and Mary F. Paine
Drug Metabolism and Disposition, 2015, 43, 34-41.
PMID: 25326286; PMCID: PMC4279085; doi: 10.1124/dmd.114.061192

Top ↑


2014

110

“Mass Spectrometry Imaging of Secondary Metabolites Directly on Fungal Cultures.”
Vincent P. Sica, Huzefa A. Raja, Tamam El-Elimat, and Nicholas H. Oberlies
RSC Advances, 2014, 4, 63221-63227.
doi: 10.1039/C4RA11564C

109

“Identification of Diet-Derived Constituents as Potent Inhibitors of Intestinal Glucuronidation.”
Brandon T. Gufford, Gang Chen, Philip Lazarus, Tyler N. Graf, Nicholas H. Oberlies, and Mary F. Paine
Drug Metabolism and Disposition, 2014, 42, 1675-1683.
PMID: 25008344; PMCID: PMC4164973; doi: 10.1124/dmd.114.059451

108

“Greensporones: Resorcylic Acid Lactones from an Aquatic Halenospora Sp.”
Tamam El-Elimat, Huzefa A. Raja, Cynthia S. Day, Wei-Lun Chen, Steven M. Swanson, and Nicholas H. Oberlies
Journal of Natural Products, 2014, 77, 2088-2098.
PMID: 25093280; PMCID: PMC4176394; doi: 10.1021/np500497r

107

“Bioactive Withanolides from Withania obtusifolia.”
Feras Q. Alali, Chiraz Soumia M. Amrine, Tamam El-Elimat, Ahmad Alkofahi, Khaled Tawaha, Mohammad Gharaibah, Steven M. Swanson, Joseph O. Falkinham III, Marisa Cabeza, Araceli Sánchez, Mario Figueroa, and Nicholas H. Oberlies
Phytochemistry Letters, 2014, 9, 96-101.
doi:10.1016/j.phytol.2014.05.002

106

“Antimycobacterial Furofuran Lignans from the Roots of Anemopsis californica.”
Robert O. Bussey III, Arlene A. Sy-Cordero, Mario Figueroa, Fredrick S. Carter, Joseph O. Falkinham III, Nicholas H. Oberlies, and Nadja B. Cech
Planta Medica, 2014, 80, 498-501.
PMID: 24687738; doi: 10.1055/s-0034-1368352

105

“Labeled Content of Two Furanocoumarins in Dietary Supplements Correlates with Neither Actual Content nor CYP3A Inhibitory Activity.”
Karen M. VanderMolen, Garrett R. Ainslie, Mary F. Paine, and Nicholas H. Oberlies
Journal of Pharmaceutical and Biomedical Analysis, 2014, 98, 260-265.
PMID: 24951959; doi: 10.1016/j.jpba.2014.05.038

104

“Identification of Isosilybin a from Milk Thistle Seeds as an Agonist of Peroxisome Proliferator-Activated Receptor Gamma.”
Eva-Maria Pferschy-Wenzig, Atanas G. Atanasov, Clemens Malainer, Stefan M. Noha, Olaf Kunert, Daniela Schuster, Elke H. Heiss, Nicholas H. Oberlies, Hildebert Wagner, Rudolf Bauer, and Verena M. Dirsch
Journal of Natural Products, 2014, 77, 842-847.
PMID: 24597776; PMCID: PMC4003856; doi: 10.1021/np400943b

103

“Epigenetic Manipulation of a Filamentous Fungus by the Proteasome-Inhibitor Bortezomib Induces the Production of an Additional Secondary Metabolite.”
Karen M. VanderMolen, Blaise A. Darveaux, Wei-Lun Chen, Steven M. Swanson, Cedric J. Pearce, and Nicholas H. Oberlies
RSC advances, 2014, 4, 18329-18335.
PMID: 24955237; PMCID: PMC4061710; doi: 10.1039/c4ra00274a

102

“Polyhydroxyanthraquinones as Quorum Sensing Inhibitors from the Guttates of Penicilliumrestrictum and Their Analysis by Desorption Electrospray Ionization Mass Spectrometry.”
Mario Figueroa, Alan K. Jarmusch, Huzefa A. Raja, Tamam El-Elimat, Jeffrey S. Kavanaugh, Alexander R. Horswill, R. Graham Cooks, Nadja B. Cech, and Nicholas H. Oberlies
Journal of Natural Products, 2014, 77, 1351-1358.
PMID: 24911880; PMCID: PMC4073659; doi: 10.1021/np5000704

101

“Isochromenones, Isobenzofuranone, and Tetrahydronaphthalenes Produced by Paraphoma radicina, a Fungus Isolated from a Freshwater Habitat.”
Tamam El-Elimat, Huzefa A. Raja, Mario Figueroa, Joseph O. Falkinham III, and Nicholas H. Oberlies
Phytochemistry, 2014, 104, 114-120.
PMID: 24833033; doi: 10.1016/j.phytochem.2014.04.006

100

“Flavonolignans from Aspergillus iizukae, a Fungal Endophyte of Milk Thistle (Silybum marianum).”
Tamam El-Elimat, Huzefa A. Raja, Tyler N. Graf, Stanley H. Faeth, Nadja B. Cech, and Nicholas H. Oberlies
Journal of Natural Products, 2014, 77, 193-199.
PMID: 24456525; doi: 10.1021/np400955q

99

“Physiologically Based Pharmacokinetic Modeling Framework for Quantitative Prediction of an Herb-Drug Interaction.”
Scott J. Brantley, Brandon T. Gufford, R Dua, Daryl J. Fediuk, Tyler N. Graf, Yolanda V. Scarlett, Kosea S. Frederick, Matthew B. Fisher, Nicholas H. Oberlies, and Mary F. Paine
CPT: Pharmacometrics & Systems Pharmacology, 2014, 3, e107.
PMID: 24670388; PMCID: PMC4042458; doi: 10.1038/psp.2013.69

Top ↑


2013

98

“Evaluation of Culture Media for the Production of Secondary Metabolites in a Natural Products Screening Program.”
Karen M. VanderMolen, Huzefa A. Raja, Tamam El-Elimat, and Nicholas H. Oberlies
AMB Express, 2013, 3, 71.
PMID: 24342059; PMCID: PMC3917616; doi: 10.1186/2191-0855-3-71

97

“High-Resolution Ms, Ms/Ms, and UV Database of Fungal Secondary Metabolites as a Dereplication Protocol for Bioactive Natural Products.”
Tamam El-Elimat, Mario Figueroa, Brandie M. Ehrmann, Nadja B. Cech, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2013, 76, 1709-1716.
PMID: 23947912; PMCID: PMC3856222; doi: 10.1021/np4004307

96

“Silibinin Inhibits Hepatitis C Virus Entry into Hepatocytes by Hindering Clathrin-Dependent Trafficking.”
Julie Blaising, Pierre L. Lévy, Claire Gondeau, Capucine Phelip, Mihayl Varbanov, Elodie Teissier, Florence Ruggiero, Stephen J. Polyak, Nicholas H. Oberlies, Tijana Ivanovic, Steeve Boulant, and Eve-Isabelle Pécheur
Cellular Microbiology, 2013, 15, 1866-1882.
PMID: 23701235; doi: 10.1111/cmi.12155

95

“Rapid Quantitation of Furanocoumarins and Flavonoids in Grapefruit Juice Using Ultra-Performance Liquid Chromatography.”
Karen M. VanderMolen, Nadja B. Cech, Mary F. Paine, and Nicholas H. Oberlies
Phytochemical Analysis, 2013, 24, 654-660.
PMID: 23780830; PMCID: PMC3855432; doi: 10.1002/pca.2449

94

“A Modified Grapefruit Juice Eliminates Two Compound Classes as Major Mediators of the Grapefruit Juice–Fexofenadine Interaction: An in Vitro–in Vivo “Connect”.”
Christina S. Won, Tian Lan, Karen M. VanderMolen, Paul A. Dawson, Nicholas H. Oberlies, Wilbur W. Widmer, Yolanda V. Scarlett, and Mary F. Paine
The Journal of Clinical Pharmacology, 2013, 53, 982-990.
PMID: 23878024; PMCID: PMC4029847; doi: 10.1002/jcph.136

93

“Waol A, Trans-Dihydrowaol A, and Cis-Dihydrowaol A: Polyketide-Derived Γ-Lactones from aVolutella Species.”
Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Audrey F. Adcock, David J. Kroll, Steven M. Swanson, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Tetrahedron Letters, 2013, 54, 4300-4302.
PMID: 23956472; PMCID: PMC3743556; doi: 10.1016/j.tetlet.2013.06.008

92

“Peptaibols, Tetramic Acid Derivatives, Isocoumarins, and Sesquiterpenes from a Bionectria Sp. (MSX 47401).”
Mario Figueroa, Huzefa Raja, Joseph O. Falkinham, Audrey F. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2013, 76, 1007-1015.
PMID: 23806109; PMCID: PMC3736820; doi: 10.1021/np3008842

91

“Mechanistic Study of the Biomimetic Synthesis of Flavonolignan Diastereoisomers in Milk Thistle.”
Hanan S. Althagafy, Maria Elena Meza-Aviña, Nicholas H. Oberlies, and Mitchell P. Croatt
The Journal of Organic Chemistry, 2013, 78, 7594-7600.
PMID: 23876147; PMCID: PMC3855429; doi: 10.1021/Jo401137

90

“A Systematic Approach to Evaluate Herb-Drug Interaction Mechanisms: Investigation of Milk Thistle Extracts and Eight Isolated Constituents as CYP3A Inhibitors.”
Scott J. Brantley, Tyler N. Graf, Nicholas H. Oberlies, and Mary F. Paine
Drug Metabolism and Disposition, 2013, 41, 1662-1670.
PMID: 23801821; PMCID: PMC3876807; doi: 10.1124/dmd.113.052563

89

“Semisynthesis, Cytotoxicity, Antiviral Activity, and Drug Interaction Liability of 7-O-Methylated Analogues of Flavonolignans from Milk Thistle.”
Hanan S. Althagafy, Tyler N. Graf, Arlene A. Sy-Cordero, Brandon T. Gufford, Mary F. Paine, Jessica Wagoner, Stephen J. Polyak, Mitchell P. Croatt, and Nicholas H. Oberlies
Bioorganic & Medicinal Chemistry, 2013, 21, 3919-3926.
PMID: 23673225; PMCID: PMC3855444; doi: 10.1016/j.bmc.2013.04.017

88

“HiFSA Fingerprinting Applied to Isomers with near-Identical NMR Spectra: The Silybin/Isosilybin Case.”
José G. Napolitano, David C. Lankin, Tyler N. Graf, J. Brent Friesen, Shao-Nong Chen, James B. McAlpine, Nicholas H. Oberlies, and Guido F. Pauli
Journal of Organic Chemistry, 2013, 78, 2827-2839.
PMID: 23461697; PMCID: PMC3640553; doi: 10.1021/jo302720h

87

“Benzoquinones and Terphenyl Compounds as Phosphodiesterase-4B Inhibitors from a Fungus of the Order Chaetothyriales (MSX 47445).”
Tamam El-Elimat, Mario Figueroa, Huzefa A. Raja, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Cynthia S. Day, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2013, 76, 382-387.
PMID: 23301853; PMCID: PMC3606633; doi: 10.1021/np300749w

86

“Silymarin for HCV Infection.”
Stephen J. Polyak, Nicholas H. Oberlies, Eve-Isabelle Pécheur, Harel Dahari, Peter Ferenci, and Jean-Michel Pawlotsky
Antiviral Therapy, 2013, 18, 141-147.
PMID: 23011959; PMCID: PMC4076489; doi: 10.3851/imp2402

85

“Interaction of Silymarin Flavonolignans with Organic Anion-Transporting Polypeptides.”
Kathleen Köck, Ying Xie, Roy L. Hawke, Nicholas H. Oberlies, and Kim L. R. Brouwer
Drug Metabolism and Disposition, 2013, 41, 958-965.
PMID: 23401473; PMCID: PMC3629808; doi: 10.1124/dmd.112.048272

84

“Sarothrin from Alkanna Orientalis Is an Antimicrobial Agent and Efflux Pump Inhibitor.”
Jessica R. Bame, Tyler N. Graf, Hiyas A. Junio, R. Owen Bussey, Scott A. Jarmusch, Tamam El-Elimat, Joseph O. Falkinham, Nicholas H. Oberlies, Richard A. Cech, and Nadja B. Cech
Planta Medica, 2013, 79, 327-329.
PMID: 23468310; doi: 10.1055/s-0032-1328259

83

“Enhanced Bioactivity of Silybin B Methylation Products.”
Arlene A. Sy-Cordero, Tyler N. Graf, Scott P. Runyon, Mansukh C. Wani, David J. Kroll, Rajesh Agarwal, Scott J. Brantley, Mary F. Paine, Stephen J. Polyak, and Nicholas H. Oberlies
Bioorganic & Medicinal Chemistry, 2013, 21, 742-747.
PMID: 23260576; PMCID: PMC3630461; doi: 10.1016/j.bmc.2012.11.035

82

“Freshwater Ascomycetes: Minutisphaera (Dothideomycetes) revisited, including one new species from Japan.”
Huzefa Raja, Kazuaki Tanaka, Kazuyuki Hirayama, Akira Hoshimoto, Nicholas H. Oberlies, Mario Figueroa, Andrew N. Miller, Steven E. Zelski, and Carol A. Shearer.
Mycologia, 2013, 105, 959-976.
PMID: 23709484; doi: 10.3852/12-313

81

Lindgomyces angustiascus, (Lindgomycetaceae, Pleosporales, Dothideomycetes), a new lignicolous species from freshwater habitats in the USA”
Huzefa Raja, Nicholas H. Oberlies, Tamama El Elimat, Andrew N. Miller, Steve Zelski, and Carol A. Shearer.
Mycoscience, 2013, 54, 353-361.
doi: 10.1016/j.myc.2012.12.004

Top ↑


2012

80

“Absolute Configuration of Isosilybin a by X-Ray Crystallography of the Heavy Atom Analogue 7-(4-Bromobenzoyl)Isosilybin A.”
Arlene A. Sy-Cordero, Cynthia S. Day, and Nicholas H. Oberlies
Journal of Natural Products, 2012, 75, 1879-1881.
PMID: 23116206; PMCID: PMC3620721; doi: 10.1021/np3005369

79

“Cytotoxic Epipolythiodioxopiperazine Alkaloids from Filamentous Fungi of the Bionectriaceae.”
Mario Figueroa, Tyler N. Graf, Sloan Ayers, Audrey F. Adcock, David J. Kroll, Jilai Yang, Steven M. Swanson, Ulyana Munoz-Acuna, Esperanza J. Carcache de Blanco, Rajesh Agrawal, Mansukh C. Wani, Blaise A. Darveaux, Cedric J. Pearce, and Nicholas H. Oberlies.
Journal of Antibiotics, 2012, 65, 559-564.
PMID: 22968289; doi: 10.1038/ja.2012.69

78

“Revisiting the Enniatins: A Review of Their Isolation, Biosynthesis, Structure Determination and Biological Activities.”
Arlene A. Sy-Cordero, Cedric J. Pearce, and Nicholas H. Oberlies.
Journal of Antibiotics, 2012, 65, 541-549.
PMID: 22990381; doi: 10.1038/ja.2012.71

77

“Use of the Hollow Fiber Assay for the Discovery of Novel Anticancer Agents from Fungi.”
Cedric J. Pearce, Daniel D. Lantvit, Qi Shen, David Jarjoura, Xiaoli Zhang, Nicholas H. Oberlies, David J. Kroll, Mansukh C. Wani, Jimmy Orjala, Djaja D. Soejarto, Norman R. Farnsworth, Esperanza J. Carcache Blanco, James R. Fuchs, A. Douglas Kinghorn, and Steven M. Swanson.
Methods in Molecular Biology 2012, 944, 267-277.
PMID: 23065624; doi: 10.1007/978-1-62703-122-6_20

76

“Mechanisms Underlying Food–Drug Interactions: Inhibition of Intestinal Metabolism and Transport.”
Christina S. Won, Nicholas H. Oberlies, and Mary F. Paine
Pharmacology & Therapeutics, 2012, 136, 186-201.
PMID: 22884524; PMCID: PMC3466398; doi: 10.1016/j.pharmthera.2012.08.001

75

“Angiopreventive Efficacy of Pure Flavonolignans from Milk Thistle Extract against Prostate Cancer: Targeting VEGF-VEGFR Signaling.”
Gagan Deep, Subhash C. Gangar, Subapriya Rajamanickam, Komal Raina, Mallikarjuna Gu, Chapla Agarwal, Nicholas H. Oberlies, and Rajesh Agarwal
PLoS One, 2012, 7, e34630.
PMID: 22514647; PMCID: PMC3326063; doi: 10.1371/journal.pone.0034630

74

“Peptaibols from Two Unidentified Fungi of the Order Hypocreales with Cytotoxic, Antibiotic, and Anthelmintic Activities.”
Sloan Ayers, Brandie M. Ehrmann, Audrey F. Adcock, David J. Kroll, Esperanza J. Carcache de Blanco, Qi Shen, Steven M. Swanson, Joseph O. Falkinham, Mansukh C. Wani, Sheila M. Mitchell, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Peptide Science, 2012, 18, 500-510.
PMID: 22744757; PMCID: PMC3494480; doi: 10.1002/psc.2425

73

“Chemical Diversity of Metabolites from Fungi, Cyanobacteria, and Plants Relative to FDA-Approved Anticancer Agents.”
Tamam El-Elimat, Xiaoli Zhang, David Jarjoura, Franklin J. Moy, Jimmy Orjala, A. Douglas Kinghorn, Cedric J. Pearce, and Nicholas H. Oberlies
ACS Medicinal Chemistry Letters, 2012, 3, 645-649.
PMID: 22993669; PMCID: PMC3443637; doi: 10.1021/ml300105s

72

“Effects of (5z)-7-Oxozeaenol on MDA-MB-231 Breast Cancer Cells.”
Ulyana Muñoz Acuña, Jennifer Wittwer, Sloan Ayers, Cedric J. Pearce, Nicholas H. Oberlies, and Esperanza J. Carcache de Blanco
Anticancer Research, 2012, 32, 2415-2421.
PMID: 22753698; http://ar.iiarjournals.org/content/32/7/2415.abstract

71

“Effects of (5z)-7-Oxozeaenol on the Oxidative Pathway of Cancer Cells.”
Ulyana Muñoz Acuña, Jennifer Wittwer, Sloan Ayers, Cedric J. Pearce, Nicholas H. Oberlies, and Esperanza J. Carcache de Blanco
Anticancer Research, 2012, 32, 2665-2671.
PMID: 22753724; http://ar.iiarjournals.org/content/32/7/2665.abstract

70

“Cytotoxic Xanthone-Anthraquinone Heterodimers from an Unidentified Fungus of the Order Hypocreales (MSX 17022).”
Sloan Ayers, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Qi Shen, Steven M. Swanson, Susan Matthew, Esperanza J. Carcache de Blanco, Mansukh C. Wani, Blaise A. Darveaux, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Antibiotics, 2012, 65, 3-8.
PMID: 22068158; doi: 10.1038/ja.2011.95

Top ↑


2011

69

“Thielavin B Methyl Ester: A Cytotoxic Benzoate Trimer from an Unidentified Fungus (MSX 55526) from the Order Sordariales.” 
Sloan Ayers, Brandie M. Ehrmann, Audrey F. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Tetrahedron Letters, 2011, 52, 5733-5735.
doi: 10.1016/j.tetlet.2011.08.125

68

“Differential in Vitro Effects of Intravenous Versus Oral Formulations of Silibinin on the HCV Life Cycle and Inflammation.”
Jessica Wagoner, Chihiro Morishima, Tyler N. Graf, Nicholas H. Oberlies, Elodie Teissier, Eve-Isabelle Pécheur, John E. Tavis, and Stephen J. Polyak
PLoS One, 2011, 6, e16464.
PMID:21297992; PMC3030583; doi: 10.1371/journal.pone.0016464

67

“Resorcylic Acid Lactones with Cytotoxic and NF-kB Inhibitory Activities and Their Structure-Activity Relationships.”
Sloan Ayers, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Susan Matthew, Esperanza J. Carcache de Blanco, Qi Shen, Steven M. Swanson, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2011, 74, 1126-1131.
PMID:21513293; PMCID: PMC3111092; doi: 10.1021/np200062x

66

“Isolation and Identification of Intestinal CYP3A Inhibitors from Cranberry (Vaccinium macrocarpon) Using Human Intestinal Microsomes.”
Eunkyung Kim, Arlene Sy-Cordero, Tyler N. Graf, Scott J. Brantley, Mary F. Paine, and Nicholas H. Oberlies
Planta Medica, 2011, 77, 265-270.
PMID:20717876; PMCID: PMC3023844; doi: 10.1055/s-0030-1250259

65

“Synergy-Directed Fractionation of Botanical Medicines: A Case Study with Goldenseal (Hydrastis canadensis).”
Hiyas A. Junio, Arlene A. Sy-Cordero, Keivan A. Ettefagh, Johnna T. Burns, Kathryn T. Micko, Tyler N. Graf, Scott J. Richter, Robert E. Cannon, Nicholas H. Oberlies, and and Nadja B. Cech
Journal of Natural Products, 2011, 74, 1621-1629.
PMID:21661731; PMCID: PMC3142294; doi: 10.1021/np200336g

64

“Obionin B: An O-Pyranonaphthoquinone Decaketide from an Unidentified Fungus (MSX 63619) from the Order Pleosporales.”
Sloan Ayers, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Qi Shen, Steven M. Swanson, Mansukh C. Wani, Blaise A. Darveaux, Cedric J. Pearce, and Nicholas H. Oberlies Tetrahedron
Letters, 2011, 52, 5128-5230.
PMID:22025810; PMCID: PMC3183506; doi: 10.1016/j.tetlet.2011.07.102

63

“Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320).”
Arlene A. Sy-Cordero, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Qi Shen, Steven M. Swanson, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2011, 74, 2137-2142.
PMID:21978324; doi: 10.1021/np2004243

“Correction to Cyclodepsipeptides, Sesquiterpenoids, and Other Cytotoxic Metabolites from the Filamentous Fungus Trichothecium sp. (MSX 51320).”
Arlene A. Sy-Cordero, Tyler N. Graf, Audrey F. Adcock, David J. Kroll, Qi Shen, Steven M. Swanson, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2012, 75, 307-307.
doi: 10.1021/np3000766

62

“Fingolimod (FTY720): A Recently Approved Multiple Sclerosis Drug Based on a Fungal Secondary Metabolite.”
Cherilyn R. Strader, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Natural Products, 2011, 74, 900-907.
PMID:21456524; doi: 10.1021/np2000528

61

“Romidepsin (Istodax, NSC 630176, FR901228, FK228, Depsipeptide): A Natural Product Recently Approved for Cutaneous T-Cell Lymphoma.”
Karen M. VanderMolen, William McCulloch, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Antibiotics, 2011, 64, 525-531.
PMID: 21587264; PMCID: PMC3163831; doi: 10.1038/ja.2011.35

Top ↑


2010

60

“The Warfarin-Cranberry Juice Interaction Revisited: A Systematic in Vitro-in Vivo Evaluation.”
Ngoc Ngo, Scott J. Brantley, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, David J. Kroll, Nicholas H. Oberlies, and Mary F. Paine
Journal of Experimental Pharmacology, 2010, 2, 83-91.
PMID:20865058; PMCID: PMC2943398; doi: 10.2147/JEP.S11719

59

“Colchicinoids from Colchicum Crocifolium Boiss. (Colchicaceae).”
Feras Q. Alali, Ahmad A. Gharaibeh, Abdullah Ghawanmeh, Khaled Tawaha, Amjad Qandil, Jason P. Burgess, Arlene Sy, Yuka Nakanishi, David J. Kroll, and Nicholas H. Oberlies
Natural Product Research, 2010, 24, 152-159.
PMID:20077308; doi: 10.1080/14786410902941097

58

“A Randomized, Controlled, Double-Blind, Pilot Study of Milk Thistle for the Treatment of Hepatotoxicity in Childhood Acute Lymphoblastic Leukemia (ALL).”
Elena J. Ladas, David J. Kroll, Nicholas H. Oberlies, Bin Cheng, Deborah H. Ndao, Susan R. Rheingold, and Kara M. Kelly
Cancer, 2010, 116, 506-513.
PMID: 20014183; doi: 10.1002/cncr.24723

57

“Dereplication of Macrocyclic Trichothecenes from Extracts of Filamentous Fungi through UV and NMR Profiles.”
Arlene A. Sy-Cordero, Tyler N. Graf, Mansukh C. Wani, David J. Kroll, Cedric J. Pearce, and Nicholas H. Oberlies
Journal of Antibiotics, 2010, 63, 539-544.
PMID:20648023; PMCID: PMC2946446; doi: 10.1038/ja.2010.77

56

“Multiple Effects of Silymarin on the Hepatitis C Virus Lifecycle.”
Jessica Wagoner, Amina Negash, Olivia J. Kane, Laura E. Martinez, Yaakov Nahmias, Nigel Bourne, David M. Owen, Joe Grove, Claire Brimacombe, Jane A. McKeating, Eve-Isabelle Pécheur, Tyler N. Graf, Nicholas H. Oberlies, Volker Lohmann, Feng Cao, John E. Tavis, and Stephen J. Polyak
Hepatology, 2010, 51, 1912-1921.
PMID:20512985; PMCID: PMC2909978; doi: 10.1002/hep.23587

55

“Identification of Hepatoprotective Flavonolignans from Silymarin.”
Stephen J. Polyak, Chihiro Morishima, Volker Lohmann, Sampa Pal, David Y. W. Lee, Yanze Liue, Tyler N. Graf, and Nicholas H. Oberlies
Proceedings of the National Academy of Sciences USA, 2010, 107, 5995-5999.
PMID: 20231449; PMCID: PMC2851903; doi: 10.1073/pnas.0914009107

54

“Two Flavonolignans from Milk Thistle (Silybum marianum) Inhibit CYP2C9-Mediated Warfarin Metabolism at Clinically Achievable Concentrations.”
Scott J. Brantley, Nicholas H. Oberlies, David J. Kroll, and Mary F. Paine
Journal of Pharmacology and Experimental Therapeutics, 2010, 332, 1081-1087.
PMID:19934397; PMCID: PMC2835426; doi: 10.1124/jpet.109.161927

53

“Large-Scale Isolation of Flavonolignans from Silybum marianum Extract Affords New Minor Constituents and Preliminary Structure-Activity Relationships.”
Arlene Sy-Cordero, Tyler N. Graf, Yuka Nakanishi, Mansukh C. Wani, Rajesh Agarwal, David J. Kroll, and Nicholas H. Oberlies
Planta Medica, 2010, 76, 644-647.
PMID:19941262; PMCID: PMC2910627; doi: 10.1055/s-0029-1240624

52

“Isosilybin A Induces Apoptosis in Human Prostate Cancer Cells Via Targeting Akt, NF-kappaB, and Androgen Receptor Signaling.”
Gagan Deep, Subhash C. Gangar, Nicholas H. Oberlies, David J. Kroll, and Rajesh Agarwal
Molecular Carcinogenesis, 2010, 49, 902-912.
PMID:20721970; doi: 10.1002/mc.20670

51

“Silymarin Inhibits in Vitro T Cell Proliferation and Cytokine Production in Hepatitis C Virus Infection.”
Chihiro Morishima, Margaret C. Shuhart, Chia C. Wang, Denise M. Paschal, Minjun C. Apodaca, Yanze Liu, Derek D. Sloan, Tyler N. Graf, Nicholas H. Oberlies, David Y.–W. Lee, Keith R. Jerome, and Stephen J. Polyak
Gastroenterology, 2010, 138, 671-681.
PMID:19782083; PMCID: PMC2819600; doi: 10.1053/j.gastro.2009.09.021

50

“Influence of Dietary Substances on Intestinal Drug Metabolism and Transport.”
Christina S. Won, Nicholas H. Oberlies, and Mary F. Paine
Current Drug Metabolism, 2010, 11, 778-792.
PMID: 21189136; PMCID: PMC3034088; http://www.benthamdirect.org/pages/content.php?CDM/2010/00000011/00000009/0006F.SGM

Top ↑


2009

49

“Mapping of Sample Collection Data: Gis Tools for the Natural Product Researcher.”
Nicholas H. Oberlies, James I. Rineer, Feras Q. Alali, Khaled Tawaha, Joseph O. Falkinham III, and William D. Wheaton
Phytochemistry Letters, 2009, 2, 1-9.
PMID: 20161345; PMCID: PMC2774915; doi: 10.1016/j.phytol.2008.10.006

48

“Identification of a Cranberry Juice Product That Inhibits Enteric CYP3A-Mediated First-Pass Metabolism in Humans.”
Ngoc Ngo, Zhixia Yan, Tyler N. Graf, Daniel R. Carrizosa, Angela D. M. Kashuba, E. Claire Dees, Nicholas H. Oberlies, and Mary F. Paine
Drug Metabolism and Disposition, 2009, 37, 514-522.
PMID: 19114462; PMCID: PMC2650736; doi: 10.1124/dmd.108.024968

47

“Proliferation of Antibiotic Producing Bacteria and Concomitant Antibiotic Production as the Basis for the Antibiotic Activity of Jordan’s Red Soils.”
Joseph O. Falkinham III, Thomas E. Wall, Justin R. Tanner, Khaled Tawaha, Feras Q. Alali, Chen Li, and Nicholas H. Oberlies
Applied and Environmental Microbiology, 2009, 75, 2735-2741.
PMID: 19286796; PMCID: PMC2681674; doi: 10.1128/AEM.00104-09

46

“Bioactive Constituents of the Stem Bark of Mitrephora Glabra.”
Chen Li, Dongho Lee, Tyler N. Graf, Sharnelle S. Phifer, Yuka Nakanishi, Soedarsono Riswan, Fransisca M. Setyowati, Achmad M. Saribi, Djaja D. Soejarto, Norman R. Farnsworth, III Joseph O. Falkinham III, David J. Kroll, A. Douglas Kinghorn, Mansukh C. Wani, and Nicholas H. Oberlies
Journal of Natural Products, 2009, 72, 1949-1953.
PMID: 19874044; PMCID: PMC2862477; doi: 10.1021/np900572g

45

“Discovery of Anticancer Agents of Diverse Natural Origin.”
A. Douglas Kinghorn, Esperanza J. Carcache de Blanco, Hee-Byung Chai, Jimmy Orjala, Norman R. Farnsworth, D. Doel Soejarto, Nicholas H. Oberlies, Mansukh C. Wani, David J. Kroll, Cedric J. Pearce, Steven M. Swanson, Robert A. Kramer, William C. Rose, Craig R. Fairchild, Gregory D. Vite, Stuart Emanuel, David Jarjoura, and Frederick O. Cope
Pure Applied Chemistry, 2009, 81, 1051-1063.
PMID: 20046887; PMCID: PMC2765058; doi: 10.1351/PAC-CON-08-10-16

Top ↑


2008

44

“Microbial-Mediated Release of Bisphenol A from Polycarbonate Vessels.”
Nicholas H. Oberlies, Chen Li, Robert J. McGivney, Feras Q. Alali, Justin R. Tanner, and Joseph O. Falkinham III
Letters in Applied Microbiology, 2008, 46, 271-275.
PMID:18069976; doi: 10.1111/j.1472-765X.2007.02301.x

43

“Colchicinoids from Colchicum Crocifolium Boiss.: A Case Study in Dereplication Strategies for (-)-Colchicine and Related Analogs Using LC-MS and LC-PDA Techniques.”
Feras Q. Alali, Ahmad Gharaibeh, Abdullah Ghawanmeh, Khaled Tawaha, and Nicholas H. Oberlies
Phytochemical Analysis, 2008, 19, 385-394.
PMID: 18444231; doi: 10.1002/pca.1060

42

“Isosilibinin Inhibits Advanced Human Prostate Cancer Growth in Athymic Nude Mice: Comparison with Silymarin and Silibinin.”
Gagan Deep, Komal Raina, Rana P. Singh, Nicholas H. Oberlies, David J. Kroll, and Rajesh Agarwal
International Journal of Cancer, 2008, 123, 2750-2758.
PMID:18798272; doi: 10.1002/ijc.23879

41

“Identifying the Differential Effects of Silymarin Constituents on Cell Growth and Cell Cycle Regulatory Molecules in Human Prostate Cancer Cells.”
Gagan Deep, Nicholas H. Oberlies, David J. Kroll, and Rajesh Agarwal
International Journal of Cancer, 2008, 123, 41-50.
PMID:18435416; doi: 10.1002/ijc.23485

40

“Isosilybin B Causes Androgen Receptor Degradation in Human Prostate Carcinoma Cells Via PI3K-Akt-Mdm2-Mediated Pathway.”
Gagan Deep, Nicholas H. Oberlies, David J. Kroll, and Rajesh Agarwal
Oncogene, 2008, 27, 3986-3998.
PMID: 18332867; doi: 10.1038/onc.2008.45

39

“Pyrrolizidine Alkaloids from Echium glomeratum (Boraginaceae).”
Feras Q. Alali, Yahya R. Tahboub, Eyad S. Ibrahim, Amjad M. Qandil, Khaled Tawaha, Jason P. Burgess, Arlene Sy, Yuka Nakanishi, David J. Kroll, and Nicholas H. Oberlies
Phytochemistry, 2008, 69, 2341-2346.
PMID:18691727; doi: 10.1016/j.phytochem.2008.06.017

Top ↑


2007

38

“A Novel Small Molecule That Selectively Inhibits Glioblastoma Cells Expressing EGFRvIII.”
Dimitri G. Trembath, Anita Lal, David J. Kroll, Nicholas H. Oberlies, and Gregory J. Riggins
Molecular Cancer, 2007, 6, 30.
PMID: 17437646; PMCID: PMC1855066; doi: 10.1186/1476-4598-6-30

37

“Antioxidant Activity and Total Phenolic Content of Aqueous and Methanolic Extracts of Jordanian Plants: An ICBG Project.”
Feras Q. Alali, Khaled Tawaha, Tamam El-Elimat, Maha Syouf, Mosa El-Fayad, Khaled Abulaila, Samara Joy Nielsen, William D. Wheaton, Joseph O. Falkinham III, and Nicholas H. Oberlies
Natural Product Research, 2007, 21, 1121-1131.
PMID: 17852749; doi: 10.1080/14786410701590285

36

“Isosilybin B and Isosilybin A Inhibit Growth, Induce G1 Arrest and Cause Apoptosis in Human Prostate Cancer LNCaP and 22Rv1 Cells.”
Gagan Deep, Nicholas H. Oberlies, David J. Kroll, and Rajesh Agarwal
Carcinogenesis, 2007, 28, 1533-1542.
PMID: 17389612; doi: 10.1093/carcin/bgm069

35

“Development of a Fluorescence-Based Assay to Screen Antiviral Drugs against Kaposi’s Sarcoma Associated Herpesvirus.”
Tamara K. Nun, David J. Kroll, Nicholas H. Oberlies, Djaja D. Soejarto, Ryan J. Case, Pius Piskaut, Teatulohi Matainaho, Chelsey Hilscher, Ling Wang, Dirk P. Dittmer, Shou-Jian Gao, and Blossom Damania
Molecular Cancer Therapeutics, 2007, 6, 2360-2370.
PMID: 17699731; doi: 10.1158/1535-7163.MCT-07-0108

34

“Variability in the Yield of Benzophenanthridine Alkaloids in Wildcrafted vs Cultivated Bloodroot (Sanguinaria canadensis L.).”
Tyler N. Graf, Keith E. Levine, Margaret E. Andrews, Jason M. Perlmutter, Samara Joy Nielsen, Jeanine M. Davis, Mansukh C. Wani, and Nicholas H. Oberlies
Journal of Agricultural and Food Chemistry, 2007, 55, 1205-1211.
PMID: 17253712; doi: 10.1021/jf062498f

33

“Alvaradoins E-N, Antitumor and Cytotoxic Anthracenone C-Glycosides from the Leaves of Alvaradoa haitiensis.”
Sharnelle S. Phifer, Dongho Lee, Eun-Kyoung Seo, Nam-Cheol Kim, Tyler N. Graf, David J. Kroll, Hernán A. Navarro, Robert A. Izydore, Francisco Jiménez, Ricardo Garcia, William C. Rose, Craig R. Fairchild, Robert Wild, Djaja D. Soejarto, Norman R. Farnsworth, A. Douglas Kinghorn, Nicholas H. Oberlies, Monroe E. Wall, and Mansukh C. Wani
Journal of Natural Products, 2007, 70, 954-961.
PMID: 17552563; PMCID: PMC2442713; doi: 10.1021/np070005a

32

“Gram-Scale Purification of Flavonolignan Diastereoisomers from Silybum marianum (Milk Thistle) Extract in Support of Preclinical in Vivo Studies for Prostate Cancer Chemoprevention.”
Tyler N. Graf, Mansukh C. Wani, Rajesh Agarwal, David J. Kroll, and Nicholas H. Oberlies
Planta Medica, 2007, 73, 1495-1501.
PMID: 17948171; doi: 10.1055/s-2007-990239

31

“Milk Thistle Nomenclature: Why It Matters in Cancer Research and Pharmacokinetic Studies.”
David J. Kroll, Heather S. Shaw, and Nicholas H. Oberlies
Integrative Cancer Therapies, 2007, 6, 110-119.
PMID: 17548790; doi: 10.1177/1534735407301825

30

“Clinical Relevance of the Small Intestine as an Organ of Drug Elimination: Drug-Fruit Juice Interactions.”
Mary F. Paine, and Nicholas H. Oberlies
Expert Opinion on Drug Metabolism & Toxicology, 2007, 3, 67-80.
PMID: 17269895; doi: 10.1517/17425255.3.1.67

Top ↑


2006

29

“A New Colchicinoid from Colchicum tauri, an Unexplored Meadow Saffron Native to Jordan.”
Feras Q. Alali, Amani S. Ma’aya’h, Ahmad Alkofahi, Amjad Qandil, Chen Li, Jason P. Burgess, Mansukh C. Wani, and Nicholas H. Oberlies
Natural Product Communications, 2006, 1, 95-99.

28

“Phytochemical Studies and Cytotoxicity Evaluations of Colchicum tunicatum Feinbr and Colchicum hierosolymitanum Feinbr (Colchicaceae): Two Native Jordanian Meadow Saffrons.”
Feras Q. Alali, Khaled Tawaha, Tamam El-Elimat, Rana Qasaymeh, Chen Li, Jason Burgess, Yuka Nakanishi, David J. Kroll, Mansukh C. Wani, and Nicholas H. Oberlies
Natural Product Research, 2006, 20, 558-566.
PMID: 16835088; doi: 10.1080/14786410500183381

27

“Dendrimer-Encapsulated Camptothecins: Increased Solubility, Cellular Uptake, and Cellular Retention Affords Enhanced Anticancer Activity in Vitro.”
Meredith T. Morgan, Yuka Nakanishi, David J. Kroll, Aaron P. Griset, Michael A. Carnahan, Michel Wathier, Nicholas H. Oberlies,Govindarajan Manikumar, Mansukh C. Wani, and Mark W. Grinstaff
Cancer Research, 2006, 66, 11913-11921.
PMID: 17178889; doi: 10.1158/0008-5472.CAN-06-2066

26

“Simple and Inexpensive Methods to Prevent Botanical Misfortune.”
David J. Kroll, Heather S. Shaw, and Nicholas H. Oberlies
Acta Horticulturae, 2006, 720, 137-147.
http://www.actahort.org/books/720/720_13.htm

Top ↑


2005

25

“New Colchicinoids from a Native Jordanian Meadow Saffron, Colchicum brachyphyllum: Isolation of the First Naturally Occurring Dextrorotary Colchicinoid.”
Feras Q. Alali, Tamam El-Elimat, Chen Li, Amjad Qandil, Ahmad Alkofahi, Khaled Tawaha, Jason P. Burgess, Yuka Nakanishi, David J. Kroll, Hernán A. Navarro, III Joseph O. Falkinham III, Mansukh C. Wani, and Nicholas H. Oberlies
Journal of Natural Products, 2005, 68, 173-178.
PMID: 15730238; doi: 10.1021/np0496587

24

“Diterpene Glycosides from Egletes viscosa.”
Dongho Lee, Chen Li, Tyler N. Graf, Jose Schunke Vigo, James G. Graham, Fernando Cabieses, Norman R. Farnsworth, Geoffrey A. Cordell, A. Douglas Kinghorn, David J. Kroll, Mansukh C. Wani, and Nicholas H. Oberlies
Planta Medica, 2005, 71, 792-794.
PMID: 16142652; doi: 10.1055/s-2005-871227

23

“A Hexacyclic Ent-Trachylobane Diterpenoid Possessing an Oxetane Ring from Mitrephora Glabra.”
Chen Li, Dongho Lee, Tyler N. Graf, Sharnelle S. Phifer, Yuka Nakanishi, Jason P. Burgess, Soedarsono Riswan, Fransisca M. Setyowati, Achmad M. Saribi, Djaja D. Soejarto, Norman R. Farnsworth, Joseph O. Falkinham III, David J. Kroll, A. Douglas Kinghorn, Mansukh C. Wani, and Nicholas H. Oberlies
Organic Letters, 2005, 7, 5709-5712.
PMID: 16321028; PMCID: PMC2442714; doi: 10.1021/ol052498l

22

“Milk Thistle and Prostate Cancer: Differential Effects of Pure Flavonolignans from Silybum marianum on Antiproliferative End Points in Human Prostate Carcinoma Cells.”
Paula R. Davis-Searles, Yuka Nakanishi, Nam-Cheol Kim, Tyler N. Graf, Nicholas H. Oberlies, Mansukh C. Wani, Monroe E. Wall, Rajesh Agarwal, and David J. Kroll
Cancer Research, 2005, 65, 4448-4457.
PMID: 15899838; doi: 10.1158/0008-5472.CAN-04-4662

21

“The Most Widely Recognized Mushroom: Chemistry of the Genus Amanita.”
Chen Li, and Nicholas H. Oberlies
Life Sciences, 2005, 78, 532-538.
PMID: 16203016; doi: 10.1016/j.lfs.2005.09.003

Top ↑


2004

20

“Analysis of Herbal Teas Made from the Leaves of Comfrey (Symphytum officinale): Reduction of N-Oxides Results in Order of Magnitude Increases in the Measurable Concentration of Pyrrolizidine Alkaloids.”
Nicholas H Oberlies, Nam-Cheol Kim, Dolores R Brine, Bradley J Collins, Robert W Handy, Charles M Sparacino, Mansukh C Wani, and Monroe E Wall
Public Health Nutrition, 2004, 7, 919-924.
PMID: 15482618; doi: 10.1079/PHN2004624

19

“Cytotoxic and Antimicrobial Constituents of the Bark of Diospyros maritima Collected in Two Geographical Locations in Indonesia.”
Jian-Qiao Gu, Tyler N. Graf, Dongho Lee, Hee-Byung Chai, Qiuwen Mi, Leonardus B. S. Kardono, Fransisca M. Setyowati, Rachman Ismail, Soedarsono Riswan, Norman R. Farnsworth, Geoffrey A. Cordell, John M. Pezzuto, Steven M. Swanson, David J. Kroll, Joseph O. Falkinham III, Monroe E. Wall, Mansukh C. Wani, A. Douglas Kinghorn, and Nicholas H. Oberlies
Journal of Natural Products, 2004, 67, 1156-1161.
PMID: 15270571; doi: 10.1021/np040027m

18

“Camptothecin and Taxol: Historic Achievements in Natural Products Research.”
Nicholas H. Oberlies, and David J. Kroll
Journal of Natural Products, 2004, 67, 129-135.
PMID: 14987046; doi: 10.1021/np030498t

Top ↑


2003

17

“Synergistic Antimicrobial Activity of Metabolites Produced by a Nonobligate Bacterial Predator.”
Cody C. Cain, Dongho Lee, Robert H. Waldo III, Alexis T. Henry, Earl J. Casida Jr., Mansukh C. Wani, Monroe E. Wall, Nicholas H. Oberlies, and Joseph O. Falkinham III
Antimicrobial Agents and Chemotherapy, 2003, 47, 2113-2117.
PMID: 12821455; PMCID: PMC161883; doi: 10.1128/AAC.47.7.2113-2117.2003

16

“Novel Strategies for the Discovery of Plant-Derived Anticancer Agents.”
A. Kinghorn, Norman Farnsworth, Djaja Soejarto, Geoffrey Cordell, Steven Swanson, John Pezzuto, Mansukh Wani, Monroe Wall, Nicholas Oberlies, David Kroll, Robert Kramer, William Rose, Gregory Vite, Craig Fairchild, Russell Peterson, and Robert Wild
Pharmaceutical Biology, 2003, 41 (Suppl.), 53-67.
http://informahealthcare.com/doi/abs/10.1080/1388020039051744

Top ↑


2002

15

“Novel Bioactive Clerodane Diterpenoids from the Leaves and Twigs of Casearia sylvestris.”
Nicholas H. Oberlies, Jason P. Burgess, Hernán A. Navarro, Rosa Elena Pinos, Craig R. Fairchild, Russell W. Peterson, Djaja D. Soejarto, Norman R. Farnsworth, A. Douglas Kinghorn, Mansukh C. Wani, and Monroe E. Wall
Journal of Natural Products, 2002, 65, 95-99.
PMID: 11858737; doi: 10.1021/np010459m

Top ↑


2001

14

“Bioactive Constituents of the Roots of Licania intrapetiolaris.”
Nicholas H. Oberlies, Jason P. Burgess, Hernán A. Navarro, Rosa Elena Pinos, Djaja D. Soejarto, Norman R. Farnsworth, A. Douglas Kinghorn, Mansukh C. Wani, and Monroe E. Wall
Journal of Natural Products, 2001, 64, 497-501.
PMID: 11325234; doi: 10.1021/np0005006

13

“Isolation of Symlandine from the Roots of Common Comfrey (Symphytum officinale) Using Countercurrent Chromatography.”
Nam-Cheol Kim, Nicholas H. Oberlies, Dolores R. Brine, Robert W. Handy, Mansukh C. Wani, and Monroe E. Wall
Journal of Natural Products, 2001, 64, 251-253.
PMID: 11430014; doi: 10.1021/np0004653

Top ↑


1998

12

“Cytotoxic and Insecticidal Constituents of the Unripe Fruit of Persea americana.”
Nicholas H. Oberlies, Lingling L. Rogers, John M. Martin, and Jerry L. McLaughlin
Journal of Natural Products, 1998, 61, 781-785.
PMID:9644064; doi: 10.1021/np9800304

11

“Myosin Isoform Shifts and Decreased Reactivity in Hypoxia-Induced Hypertensive Pulmonary Arterial Muscle.”
C. Subah Packer, Janet E. Roepke, Nicholas H. Oberlies, and Rodney A. Rhoades
American Journal of Physiology, 1998, 274, L775-L785.
PMID: 9612293; http://ajplung.physiology.org/content/274/5/L775.short 

Top ↑


1997

10

“The Annonaceous Acetogenin Bullatacin Is Cytotoxic against Multidrug Resistant Human Mammary Adenocarcinoma Cells.”
Nicholas H. Oberlies, Vicki L. Croy, Marietta L. Harrison, and Jerry L. McLaughlin
Cancer Letters, 1997, 115, 73-79.
PMID: 9097981; doi: 10.1016/S0304-3835(97)04716-2

9

“Comparative SAR Evaluations of Annonaceous Acetogenins for Pesticidal Activity.”
Kan He, Lu Zeng, Qing Ye, Guoen Shi, Nicholas H. Oberlies, Geng-Xian Zhao, C. Jesse Njoku, and Jerry L. McLaughlin
Pesticide Science, 1997, 49, 372-379.
doi: 10.1002/(SICI)1096-9063(199704)49:4<372::AID-PS543>3.0.CO;2-K

8

“Oleanolic Acid, a Bioactive Component of the Leaves of Ocimum gratissimum (Lamiaceae).”
C.J. Njoku, Lu Zeng, I.U. Asuzu, Nicholas H. Oberlies, and Jerry L. McLaughlin
Pharmaceutical Biology, 1997, 35, 134-137.
doi: 10.1076/phbi.35.2.134.13290

7

“Structure-Activity Relationships of Diverse Annonaceous Acetogenins against Multidrug Resistant Human Mammary Adenocarcinoma (MCF-7/Adr) Cells.”
Nicholas H. Oberlies, Ching-jer Chang, and Jerry L. McLaughlin
Journal of Medicinal Chemistry, 1997, 40, 2102-2106.
PMID: 9207950; doi: 10.1021/jm9700169

Top ↑


1996

6

“Longimicins A-D: Novel Bioactive Acetogenins from Asimina longifolia (Annonaceae), and Structure Activity Relationships of Asimicin Type Annonaceous Acetogenins.”
Qing Ye, Kan He, Nicholas H. Oberlies, Lu Zeng, Guoen Shi, Dean Evert, and Jerry L. McLaughlin
Journal of Medicinal Chemistry, 1996, 39, 1790-1796.
PMID: 8627602; doi: 10.1021/jm9600510

5

“Five New Monotetrahydrofuran Ring Acetogenins from the Leaves of Annona muricata.”
Lu Zeng, Feng-E Wu, Nicholas H. Oberlies, and Jerry L. McLaughlin
Journal of Natural Products, 1996, 59, 1035-1042.
PMID: 8946744; doi: 10.1021/np960447e

4

“Recent Advances in Annonaceous Acetogenins.”
Lu Zeng, Qing Ye, Nicholas H. Oberlies, Guoen Shi, Zhe-Ming Gu, Kan He, and Jerry L. McLaughlin
Natural Products Reports, 1996, 13, 275-306.
PMID: 8760865; doi: 10.1039/NP9961300275

Top ↑


1995

3

“Tumor Cell Growth Inhibition by Several Annonaceous Acetogenins in an in Vitro Disk Diffusion Assay.”
Nicholas H. Oberlies, Julie L. Jones, Thomas H. Corbett, Sophia S. Fotopoulos, and Jerry L. McLaughlin
Cancer Letters, 1995, 96, 55-62.
PMID: 7553608; doi: 10.1016/0304-3835(95)92759-7

2

“Mode of Action of Bullatacin, a Potent Antitumor Acetogenin: Inhibition of NADH Oxidase Activity of HeLa and HL-60, but Not Liver, Plasma Membranes.”
D. James Morré, Rafael de Cabo, Christopher Farley, Nicholas H. Oberlies, and Jerry L. McLaughlin
Life Sciences, 1995, 56, 343-348.
PMID: 7837933; doi: 10.1016/0024-3205(94)00957-0

Top ↑


1993

1

“The Electrochemical Preparation and Kinetic and Product Studies of Acylated Quinol and Quinol Ether Imines – in Search of the Hydrolysis Products of the Ultimate Carcinogen of N-Acetyl-2-Aminofluorene.”
Michael Novak, John S. Helmick, Nicholas Oberlies, Kanchugarakoppal S. Rangappa, William M. Clark, and John S. Swenton
Journal of Organic Chemistry, 1993, 58, 867-878.
doi: 10.1021/jo00056a019 

Top ↑