Publications

Neutral iridium(III) complexes bearing BODIPY-substituted N-heterocyclic carbene (NHC) ligands: synthesis, photophysics, in vitro theranostic photodynamic therapy, and antimicrobial activity. Photochem. Photobiol. Sci., 2019 (accepted)

A New Class of Homoleptic and Heteroleptic Bis(terpyridine) Iridium(III) Complexes with Strong Photodynamic Therapy Effects. ACS Appl. Bio Mater., 2019 (2) 2964-2977. DOI: 10.1021/acsabm.9b00312

Monocationic Iridium(III) Complexes with Far−Red Charge Transfer Absorption and Near−IR Emission: Synthesis, Photophysics, and Reverse Saturable Absorption. Eur. J. Inorg. Chem, 2019, accepted. DOI: doi.org/10.1002/ejic.201900156

Predictive Strength of Photophysical Measurements for In Vitro Photobiological Activity in a Series of Ru(II) Polypyridyl Complexes Derived from π-Extended Ligands. Inorg. Chem., 2019 (58) 3156–3166. DOI: 10.1021/acs.inorgchem.8b03223

Heteroleptic Ir(III)N6 Complexes with Long-Lived Triplet Excited States and In Vitro Photobiological Activities. ACS Appl. Mater. Interfaces, 2019 (11) 3629–3644. DOI: 10.1021/acsami.8b14744

S,S-Chiral Linker Induced U-Shape with a Syn-facial Sensitizer and Photocleavable Ethene Group. Photochem. Photobiol., 2019 (95) 293-305, DOI: 10.1111/php.13000

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433. Chem. Rev. 2019 (119) 797-828 (invited) DOI: 10.1021/acs.chemrev.8b00211

Synthesis, Characterization, and Photobiological Studies of Ru(II) Dyads Derived from α-Oligothiophene Derivatives of 1,10-Phenanthroline. Photochem. Photobiol., 2019 (95) 267-279 (invited) DOI: 10.1111/php.13012

Photodynamic Inactivation of Herpes Simplex Viruses. Viruses, Viruses 2018, 10, 532; DOI: 10.3390/v10100532

Photophysical and Photobiological Properties of Dinuclear Iridium(III) Bis-tridentate Complexes. Inorg. Chem., 2018, 57, 9859–9872 DOI: 10.1021/acs.inorgchem.8b00789

Cyclometalated Ruthenium(II) Complexes Derived from α‑Oligothiophenes as Highly Selective Cytotoxic or Photocytotoxic Agents. Inorg. Chem, 2018, 57, 7694-7712 DOI: 10.1021/acs.inorgchem.8b00689

Dying to be noticed: Epigenetic regulation of immunogenic cell death for cancer immunotherapy. Front. Immunol., 2018, 9, 654. DOI: 10.3389/fimmu.2018.00654

Excited State Dynamics of a Photobiologically Active Ru(II) Dyad are Altered in Biologically Relevant Environments. J. Phys. Chem. A., 2017, 121 5635-5644. DOI: 10.1021/acs.jpca.7b04670

Near-Infrared-Emitting Heteroleptic Cationic Iridium Complexes Derived from 2,3-Diphenylbenzo[g]quinoxaline as In Vitro Theranostic Photodynamic Therapy Agents. Dalton Trans. 2017, 46, 8091-8103. DOI: 10.1039/C7DT00913E

Synthesis and Photobiological Activity of Ru(II) Dyads Derived from Pyrrole-2-Carboxylate Thionoesters. Inorg. Chem. 2017 56(7) 4121-4132 DOI: 10.1021/acs.inorgchem.7b00072

Novel Osmium-Based Coordination Complexes as Photosensitizers for Panchromatic Photodynamic Therapy. Photochem. Photobiol. 2017, 93, 1248-1258. (Selected as highlight) DOI: 10.1111/php.12767

π‐Expansive Heteroleptic Ruthenium(II) Complexes as Reverse Saturable Absorbers and Photosensitizers for Photodynamic Therapy: Inorg. Chem. 2017, 56(6), 3245-3259. DOI: 10.1021/acs.inorgchem.6b02624

Increasing the Triplet Lifetime and Extending the Ground-State Absorption of Cationic Biscyclometalated Ir(III) Complexes by Tuning Ligand π-Conjugation for Applications in Reverse Saturable Absorption and Photodynamic Therapy: Dalt. Trans., 2016, 45, 16366-16378. DOI: 10.1039/c6dt02416e

Influence of Protonation State on the Excited State Dynamics of a Photobiologically Active Ru(II) Dyad: J. Phys. Chem. A, 2016, 120, 6379-6388. DOI: 10.1021/acs.jpca.6b05957

Strained Ruthenium Metal-Organic Dyads as Photocisplatin Agents with Dual Action: J. Inorg. Biochem. 2016, 158, 45-54. DOI: 10.1016/j.jinorgbio.2016.01.009

A Spectroscopic Study of Substituted Anthranilic Acids as Sensitive Environmental Probes for Detecting Cancer Cells: Bioorg. Med. Chem., 2016, 24, 929-937. DOI: 10.1016/j.bmc.2015.12.044

Organometallic Ru(II) Photosensitizers Derived from π‐Expansive Cyclometalating Ligands: Surprising Theranostic PDT Effects: Inorg. Chem., 2016, 55, 83–95. DOI: 10.1021/acs.inorgchem.5b01838

Isolation and Synthetic Diversification of Jadomycin 4‐Amino‐L‐phenylalanine: J. Nat. Prod., 2015, 78, 1208-1214. DOI: 10.1021/np5009398

Photophysics of Ru(II) Dyads Derived from Pyrenyl-Substitued Imidazo[4,5-f][1,10]Phenanthroline Ligands: J. Phys. Chem. A, 2015, 119, 3986–3994. DOI:10.1021/acs.jpca.5b01737

Eight-Membered Ring-Containing Jadomycins: Implications for Non-enzymatic Natural Products Biosynthesis: J. Am. Chem. Soc., 2015, 137, 3271-3275. DOI:10.1021/ja5114672

Ru(II) Dyads Derived from α-Oligothiophenes: a New Class of Potent and Versatile Photosensitizers for PDT: Coord. Chem. Rev., 2015, 282-283, 127-138. DOI 10.1016/j.ccr.2014.04.012

Ru(II) Dyads Derived from 2-(1-Pyrenyl)-1H-imidazo[4,5-f][1,10]phenanthroline: Versatile Photosensitizers for Photodynamic Applications: J. Phys. Chem. A, 2014, 118, 10507-10521. DOI:10.1021/jp504330s

Synthesis and Antimalarial Activity of Prodigiosenes: Org. Biomol. Chem., 2014, 12, 4132-4142. DOI:10.1039/C3OB42548G

In Vitro Multiwavelength PDT with ³IL States: Teaching Old Molecules New Tricks: Inorg. Chem., 2014, 53, 4548−4559. DOI 10.1021/ic5002368

Exploitation of Long-Lived ³IL Excited States for Metal−Organic Photodynamic Therapy: Verification in a Metastatic Melanoma Model: J. Am. Chem. Soc., 2013, 135, 17161−17175. DOI 10.1021/ja408426z

Synthetic prodigiosenes and the influence of C-ring substitution on DNA cleavage, transmembrane chloride transport and basicity: Org. Biomol. Chem., 2013, 11, 3834–3845. DOI 10.1039/c3ob40477c

Photodynamic inactivation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with Ru(II)-based type I/type II photosensitizers: Photodiag. Photodyn. Ther., 2013, 10, 615-625.  DOI 10.1016/j.pdpdt.2013.07.001

Investigations regarding the utility of prodigiosenes to treat leukemia: Org. Biomol. Chem., 2012, 11, 62-68. DOI 10.1039/c2ob26535d

Synthetic diversification of natural products: semi-synthesis and evaluation of triazole jadomycins: Chem. Sci., 2012, 3, 1640–1644. DOI 10.1039/c2sc00663d

Platinum-oxazoline complexes as anti-cancer agents: syntheses, characterisation and initial biological studies: Med. Chem. Commun., 2011, 2, 274–277. DOI 10.1039/c0md00211a

Copper-mediated nuclease activity of jadomycin B: Bioorg. Med. Chem., 2011, 19, 3357–3360. DOI 10.1021/ic902427r

Jadomycins Derived from the Assimilation and Incorporation of Norvaline and Norleucine: J. Nat. Prod. 2011, 74, 2420−2424. DOI 10.1021/np200689w

Photobiological Activity of Ru(II) Dyads Based on (Pyren-1-yl)ethynyl Derivatives of 1,10-Phenanthroline: Inorg. Chem. 2010, 49, 2889–2900. DOI: 10.1021/ic902427r

Diverse DNA-Cleaving Capacities of the Jadomycins through Precursor-Directed Biosynthesis: Org. Lett., 2010, 12, 1172-1175. DOI 10.1021/ol902907r

Nonthermalized excited states in Ru(II) polypyridyl complexes probed by ultrafast transient absorbtion spectroscopy with high photon energy excitation: Can. J. Chem., 2008, 86, 1118-1125. DOI 10/1139/V08-161

Picosecond Dynamics of Nonthermalized Excited States in Tris(2,2-bipyridine)ruthenium(II) Derivatives Elucidated by High Energy Excitation: J. Am. Chem. Soc., 2005, 127, 7065-7070. DOI 10.1021/ja0461872

Conformational Control of Excited-State Dynamics in Highly Distorted Ru(II) Polypyridyl Complexes: Inorg. Chem., 2005, 44, 4066-4076. DOI 10.1021/ic0502729

Modulating the efficiency of Ru(II) luminescence via ion binding-induced conformational restriction of bipyridyl ligands: Chem. Commun., 2003, 3, 388–389. DOI 10.1039/b210254d

Fluorescent Signaling Based on Control of Excited State Dynamics. Biarylacetylene Fluorescent Chemosensors: J. Am. Chem. Soc., 2002, 124, 1178-1179. DOI 10.1021/ja017309i

Fluorescent Chemosensors Based on Conformational Restriction of a Biaryl Fluorophore: J. Am. Chem. Soc. 2001, 123, 1260-1261. DOI 10.1021/ja005701a