Publications

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2019

33

“Metal‐Catalyzed Dehydration of Primary Amides to Nitriles”
Mohammed H. Al-Huniti and Mitchell P. Croatt
Asian Journal of Organic Chemistry 2019, Early View.

https://onlinelibrary.wiley.com/doi/10.1002/ajoc.201900343

32

“Synthetic Approaches to Isocarbacyclin and Analogues as Potential Neuroprotective Agents Against Ischemic Stroke”
Ghina’a I. Abu Deiab and Mitchell P. Croatt
Bioorganic & Medicinal Chemistry 2019, 27, 338-342.

https://www.sciencedirect.com/science/article/pii/S0968089618318972?via%3Dihub

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2018

31

“Palladium-Catalyzed Chemoselective Protodecarboxylation of Polyenoic Acids”
Mohammed H. Al-Huniti, Mark A. Perez, Matthew K. Garr, and Mitchell P. Croatt
Organic Letters 2018, 23, 7375-7379.

https://pubs.acs.org/doi/10.1021/acs.orglett.8b03016

30
“DFT Mechanistic Investigation of an Enantioselective Tsuji-Trost Allylation Reaction”
Kate E. McPherson, Mitchell P. Croatt, Andrew T. Morehead, Jr., and Andrew L. Sargent
Organometallics 201837, 3791-3802.

https://pubs.acs.org/doi/full/10.1021/acs.organomet.8b00507

29

“Development and Utilization of a Palladium-Catalyzed Dehydration of Primary Amides To Form Nitriles”
Mohammed H. Al-Huniti, José Rivera-Chávez, Katsuya L. Colón, Jarrod L. Stanley, Joanna E. Burdette, Cedric J. Pearce, Nicholas H. Oberlies, and Mitchell P. Croatt
Organic Letters 2018, 20, 6046-6050.

https://pubs.acs.org/doi/10.1021/acs.orglett.8b02422

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2017

28

“Hypervalent Iodonium Alkynyl Triflate Generated Phenylcyanocarbene and Its Reactivity with Aromatic Systems”
Mohammed H. Al-Huniti, Zachary B. Sullivan, Jarrod L. Stanley, James A. Carson, I. F. Dempsey Hyatt, A. Christina Hairston, and Mitchell P. Croatt
Journal of Organic Chemistry 2017, 82, 11772-11780.

http://pubs.acs.org/doi/10.1021/acs.joc.7b01608

(Special Issue on Hypervalent Iodine)

27

“Chemoselective fluorination and chemoinformatic analysis of griseofulvin: natural vs fluorinated fungal metabolites”
Noemi D. Paguigan, Mohammed Al-Huniti, Huzefa A. Raja, Austin Czarnecki, Joanna E. Burdette, Mariana González-Medina, José L. Medina-Franco, Stephen J. Polyak, Cedric J. Pearce, Mitchell P. Croatt, Nicholas H. Oberlies
Bioorganic & Medicinal Chemistry 2017, 25, 5238-5246.

http://www.sciencedirect.com/science/article/pii/S0968089617306521

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26

“Design, synthesis and biological evaluation of GPR55 agonists”
Lara Fakhouri, Christopher D. Cook, Mohammed H. Al-Huniti, Linda M. Console-Bram, Dow P. Hurst, Michael B.S. Spano, Daniel J. Nasrallah, Marc G. Caron, Larry S. Barak, Patricia H. Reggio, Mary E. Abood, Mitchell P. Croatt
Bioorganic & Medicinal Chemistry 201725, 4355-4367.

http://www.sciencedirect.com/science/article/pii/S0968089617306521

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25

“Decarboxylative and dehydrative coupling of dienoic acids and pentadienyl alcohols to form 1,3,6,8-tetraenes”
Ghina’a I. Abu Deiab, Mohammed H. Al-Huniti, I. F. Dempsey Hyatt, Emma E. Nagy, Kristen E. Gettys, Sommayah S. Sayed, Christine M. Joliat, Paige E. Daniel, Rupa M. Vummalaneni, Andrew T. Morehead Jr, Andrew L. Sargent and Mitchell P. Croatt
Beilstein Journal of Organic Chemistry 201713, 384-392.
https://www.beilstein-journals.org/bjoc/articles/13/41

1860-5397-13-41

24

“Structure-Activity Relationships of Benzothiazole GPR35 Antagonists”
Manahil M. Abdalhameed, Pingwei Zhao, Dow P. Hurst, Patricia H. Reggio, Mary E. Abood, and Mitchell P. Croatt
Bioorganic & Medicinal Chemistry Letters 201727, 612-615.
http://www.sciencedirect.com/science/article/pii/S0960894X16312793

Image for unlabelled figure

23

“Step-Economical Synthesis of Clinprost and Analogues Utilizing a Novel Decarboxylation Reaction”
Ghina’a I. Abu-Deiab and Mitchell P. Croatt
In Strategies and Tactics in Organic Synthesis Harmata, M. Ed.; Academic Press, 2017, Vol. 12, pp 95-117;
http://www.sciencedirect.com/science/article/pii/B9780081007563000030

isocarbbookch

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2016

22

“Design, Synthesis, and Analysis of Antagonists of GPR55:  Piperidine-Substituted 1,3,4-oxadiazol-2-ones”
Maria Elena Meza-Avina, Mary A. Lingerfelt, Linda Console-Bram, Thomas F. Gamage, Haleli Sharir, Kristen E. Gettys, Dow P. Hurst, Evangelia Kotsikorou, Derek M Shore, Marc G. Caron, Narasinga Rao, Larry S. Barak, Mary E Abood, Patricia H. Reggio, and Mitchell P Croatt
Bioorganic & Medicinal Chemistry Letters 201626, 1827-1830.
http://www.sciencedirect.com/science/article/pii/S0960894X16301421

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2015

21

Spiroscytalin, a New Tetramic Acid and Other Metabolites of Mixed Biogenesis from Scytalidium cuboideum
Arlene A. Sy-Cordero, Mario Figueroa, Huzefa A. Raja, Maria Elena Meza-Avina, Mitchell P. Croatt, Audrey R. Adcock, David J. Kroll, Mansukh C. Wani, Cedric J. Pearce, and Nicholas H. Oberlies
Tetrahedron 201571, 8899-8904.
http://www.sciencedirect.com/science/article/pii/S0040402015300971

Ref21

20

Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analogues”
Lara Fakhouri, Tamam El-Elimat, Dow P. Hurst, Patricia H. Reggio, Cedric J. Pearce, Nicholas H. Oberlies, and Mitchell P. Croatt
Bioorganic & Medicinal Chemistry 201523, 6993-6999.
http://www.sciencedirect.com/science/article/pii/S0968089615300626

Ref20

19

Formation and in situ reactions of hypervalent iodonium alkynyl triflates to form cyanocarbenes”
I. F. Dempsey Hyatt, Daniel J. Nasrallah, Michael A. Maxwell, A. Christina F. Hairston, Manahil M. Abdalhameed, and Mitchell P. Croatt
Chemical Communications 201551, 5287-5289.
http://pubs.rsc.org/en/content/articlelanding/2015/cc/c4cc08676g/unauth#!divRelatedContent

ChemCommGraphic

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2014

18

“Rhodium(I)-Catalyzed [2+2+2+2] Cycloaddition of Diynes to Form Cyclooctatetraenes”
Daniel J. Nasrallah and Mitchell P Croatt
European Journal of Organic Chemistry 20142014, 3767-3772.
http://dx.doi.org/10.1002/ejoc.201402109

cot

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2013

17

“Identification of the GPR55 Antagonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands”
Evangelia Kotsikorou, Haleli Sharir, Derek M Shore, Dow P. Hurst, Diane L. Lynch, Karla E. Madrigal, Susanne Heynen-Genel, Loribelle B. Milan, Thomas D.Y. Chung, Herbert H. Seltzman, Yushi Bai, Marc G. Caron, Lawrence S. Barak, Mitchell P Croatt, Mary E Abood, and Patricia H. Reggio
Biochemistry 201352, 9456-9469.
http://pubs.acs.org/doi/abs/10.1021/bi4008885

biochem

16

“Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes”
I. F. Dempsey Hyatt, Daniel J. Nasrallah, Mitchell P. Croatt
Journal of Visualized Experiments 201379, e50886. doi:10.3791/50866.
http://www.jove.com/video/50886/synthesis-hypervalent-iodonium-alkynyl-triflates-for-application

15

“Mechanistic Study of the Biomimetic Synthesis of Flavonolignan Diastereoisomers in Milk Thistle”
Hanan S. Althagafy, Maria Elena Meza-Aviña, Nicholas H. Oberlies, Mitchell P. Croatt
Journal of Organic Chemistry 201378, 7594-7600.
http://pubs.acs.org/doi/abs/10.1021/jo4011377

JOCTOC

14

“Exploring the reactivity of 1,5-disubstituted sulfonyl-triazoles: Thermolysis and Rh(II)-catalyzed synthesis of α-sulfonyl nitriles”
Maria Elena Meza-Aviña, Mudita Kishor Patel, and Mitchell P. Croatt
Tetrahedron 201369, 7840-7846.
http://www.sciencedirect.com/science/article/pii/S0040402013007837
(Special Issue in Honor of Professor Wender)

TetrahedronGraphic

13

“Semisynthesis, cytotoxicity, antiviral activity, and drug interaction liability of 7-O-methylated analogues of flavonolignans from milk thistle”
Hanan S. Althagafy, Tyler N. Graf, Arlene A. Sy-Cordero, Brandon T. Gufford, Mary F. Paine, Jessica Wagoner, Stephen J. Polyak, Mitchell P. Croatt, Nicholas H. Oberlies
Bioorganic & Medicinal Chemistry 201321, 3919-3926.
http://www.sciencedirect.com/science/article/pii/S0968089613003349

BMCgraphic

12

“Sequential Pd(0)-, Rh(I)-, and Ru(II)-catalyzed Reactions in a Nine-step Synthesis of Clinprost”
Emma E. Nagy, I. F. Dempsey Hyatt, Kristen E. Gettys, Shawn T. Yeazell, Stephen K. Frempong Jr., and Mitchell P. Croatt
Organic Letters 201315, 586-589.
http://pubs.acs.org/doi/abs/10.1021/ol303402e
(Highlighted in SYNFACTS 20139, 470)

2013OrgLett

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2012

11

“Alkynes and Azides:  Not Just for Click Reactions”
I. F. Dempsey Hyatt, Maria Elena Meza-Aviña, and Mitchell P. Croatt
Synlett 2012, 23, 2869-2874.
https://www.thieme-connect.com/ejournals/abstract/10.1055/s-0032-1317545
(Invited SYNPACTS article)

SynlettGraphic

10

“Reactions of Hypervalent Iodonium-Alkynyl Triflates with Azides: New Mechanistic Approach for the Generation of Cyanocarbenes”
I. F. Dempsey Hyatt, Mitchell P. Croatt
http://onlinelibrary.wiley.com/doi/10.1002/anie.201203062/abstract
(Featured with the Front Cover Graphic of that issue of Angew. Chem., Int. Ed. and Highlighted in Angew. Chem. Int. Ed. 201251, 12169-12171.)

reactions

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2011

9

“Selective Formation of 1,5-Substituted Sulfonyl Triazoles Using Acetylides and Sulfonyl Azides”
Maria Elena Meza-Aviña, Mudita Kishor Patel, Cylivia B. Lee, Thomas J. Dietz, Mitchell P. Croatt
Organic Letters 201113, 2984-2987;
http://pubs.acs.org/doi/full/10.1021/ol200696q
(Highlighted in SYNFACTS 20119, 1005)

selectiveformulation

8

“Probing the Role of the Mycosamine C2′-OH on the Activity of Amphotericin B.”
Mitchell P. Croatt, Erick M. Carreira
Organic Letters 201113, 1390-1393;
http://pubs.acs.org/doi/full/10.1021/ol2000765

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2010

7

“The Diene Effect: The Design, Development, and Mechanistic Investigation of Metal-Catalyzed Diene-yne, Diene-ene, and Diene-allene [2+2+1] Cycloaddition Reactions”
Mitchell P. Croatt, Paul A. Wender.
European Journal of Organic Chemistry 20102010, 19-32;
http://onlinelibrary.wiley.com/doi/10.1002/ejoc.200900929/abstract

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2009

6

“Rhodium(I)-Catalyzed [2+2], [2+2+2], and [2+2+2+2] Cycloadditions of Dienes or Alkynes with a Bis-ene”
Paul A. Wender, Mitchell P. Croatt, Björn Kühn
Organometallics 200928, 5841-5844;
http://pubs.acs.org/doi/abs/10.1021/om9007373

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2007

5

“Higher Order Cycloadditions”
Paul A. Wender, Mitchell P. Croatt, Nicole M. Deschamps
In Comprehensive Organometallic Chemistry III; Crabtree, R. H.; Mingos, D. M. P. Eds.; Elsevier: Oxford, 2007Vol. 10, pp 603-648;
http://www.elsevier.com/wps/find/bookdescription.cws_home/721739/description

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2006

4

“Metal-Catalyzed [2+2+1] Cycloadditions of 1,3-Dienes, Allenes, and CO”
Paul A. Wender, Mitchell P. Croatt, Nicole M. Deschamps
Angewandte Chemie International Edition 200645, 2459-2462;
http://onlinelibrary.wiley.com/doi/10.1002/anie.200600300/abstract

3

“Carbonyl(chloro)bis(triphenylphosphine)rhodium(I)”
Mitchell P. Croatt, Travis J. Williams, Paul A. Wender
Encyclopedia of Reagents for Organic Synthesis John Wiley & Sons, Ltd., 2006, online;
http://onlinelibrary.wiley.com/o/eros/articles/rc021/frame.html

2

“New reactions and step economy: the total synthesis of (±)-salsolene oxide based on the type II transition metal-catalyzed intramolecular [4+4] cycloaddition”
Paul A. Wender, Mitchell P. Croatt, Bernhard Witulski
Tetrahedron 200662, 7505-7511;
http://www.sciencedirect.com/science/article/pii/S0040402006006740

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2004

1

“Rhodium(I)-Catalyzed [2+2+1] Cycloadditions of 1,3-Dienes, Alkenes, and CO”
Paul A. Wender, Mitchell P. Croatt, Nicole M. Deschamps
Journal of the American Chemical Society 2004126, 5948-5949;
http://pubs.acs.org/doi/abs/10.1021/ja0489487

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