News & Events
Dr. Jon C. Antilla
Posted on February 20, 2015
Date - February 20, 2015
1:00 pm - 2:00 pm
University of South Florida, Department of Chemistry
“Reaction Methodology Utilizing Chiral Phosphate Derived Catalysts”
Organocatalysis is considered by many to be an attractive, and potential “green” alternative to traditional metal-based catalysis. This research specifically seeks to develop new reaction methodologies that utilize chiral phosphoric acids as functional asymmetric organocatalysts for synthetically useful transformations. Another way to utilize chiral phosphoric acids is to use them as a starting point to form new chiral organocatalysts or even metal catalysts with phosphate ligands. Our initial discoveries and our most recent developments that allow for the asymmetric allylation and propargylation of aldehydes will be highlighted. In addition I will discuss the use of chiral phosphoric acid derived catalysts for use in the enantioselective reduction of ketones and also show a highlight of our work in synthesis.