News & Events

When

Date - November 9, 2022
1:00 pm - 2:00 pm

What

Literature Seminar
Department of Chemistry & Biochemistry
UNC Greensboro
Oberlies Research Group
Title: Co-Culture as an Efficient Biotechnology Tool for Mining Hidden Biosynthetic Potential

Abstract:

Microorganisms do not live in isolation in nature but coinhabit all environments. They usually exchange and share chemical signals including secondary metabolites (SMs). There is general consensus that the interaction among microorganisms constitutes a driving force for the production of SMs. However, standard laboratory cultivation normally omits the complex microbial community, which may affect SM production. To exploit the hidden SM treasure, cocultivation becomes a potential strategy to stimulate SM biosynthesis. It has successfully applied to discover new bioactive metabolites and new chemical scaffolds.1:01